A Centralized Report on Pediatric Japanese Encephalitis Cases from Beijing Children's Hospital, 2013

• Published in: Biomedical and environmental sciences Vol. 29; no. 12; p. 902
• Main Authors: Li, Jiu Wei, Gao, Xiao Yan, Wu, Yun, Fu, Shi Hong, Tan, Xiao Juan, Cao, Yu Xi, Zhang, Wei Hua, Yin, Zun Dong, He, Ying, Li, Yi Xing, Liang, Guo Dong, Xu, Wen Bo, Fang, Fang, Wang, Huan Yu
• Format: Journal Article
• Language: English
• Published: Netherlands 01-12-2016
• Subjects: Beijing - epidemiology; Child; Child, Preschool; Encephalitis Virus, Japanese - physiology; Encephalitis, Japanese - diagnosis; Encephalitis, Japanese - epidemiology; Encephalitis, Japanese - virology; Female; Humans; Japanese Encephalitis Vaccines - administration & dosage; Male; Prognosis; Pediatric; Prognoses; Japanese encephalitis
• ISSN: 0895-3988
• DOI: 10.3967/bes2016.121

Fifteen pediatric cases of suspected Japanese encephalitis (JE) were reported in Beijing Children's Hospital during the late summer of 2013. The clinical manifestations in most cases included high fever, seizures, and abnormal magnetic resonance imaging findings. Twelve of 15 cases were laboratory-confirmed as JE cases by pathogen identification. Epidemiological investigations showed that five of the 12 laboratory-confirmed patients had an incomplete JE vaccination history. Follow-up investigations after discharge indicated that seven laboratory-confirmed JE patients without JE vaccinations had relatively poor prognoses, with an average Modified Rankin Scale (MRS) score of 2.6 when compared with the other five laboratory-confirmed, JE-vaccinated patients with an average MRS score of 0.5. The observation of pediatric JE cases among those with a history of JE vaccination warrants further attention.