A physiological concentration of anandamide promotes the migration of human endometrial fibroblast and the interaction with endothelial cells invitro

The mechanisms that govern fibroblast behavior during the vascular adaptations of the uterus at early pregnancy remain unknown. Anandamide, an endocannabinoid, binds to cannabinoid receptors (CBs), and regulates gestation and angiogenesis. Its tone is regulated by fatty acid amide hydrolase (FAAH) w...

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Bibliographic Details
Published in:	Placenta (Eastbourne) Vol. 139; pp. 99 - 111
Main Authors:	Cañumil, Vanesa A., de la Cruz Borthiry, Fernanda L., Scheffer, Frida, Herrero, Yamila, Scotti, Leopoldina, Bogetti, María Eugenia, Parborell, Fernanda, Meresman, Gabriela F., Franchi, Ana M., Beltrame, Jimena S., Ribeiro, María L.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-08-2023
Subjects:	Amidohydrolases - genetics Amidohydrolases - metabolism Anandamide Culture Media, Conditioned Endocannabinoids - pharmacology Endometrium Endothelial cells Endothelial Cells - metabolism Female Fibroblasts - metabolism Humans Migration Pregnancy Prostaglandin-Endoperoxide Synthases Stromal fibroblasts Vascular remodeling Vascular remodeling CB2 FAAH Stromal fibroblasts CB1 COX-2 Migration AEA Endometrium Endothelial cells Anandamide
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