Optical coherence tomography angiography based prognostic factors and visual outcomes in primary rhegmatogenous retinal detachment after pars plana vitrectomy

• Published in: International journal of retina and vitreous Vol. 10; no. 1; pp. 57 - 8
• Main Authors: Torres-Costa, Sónia, Ribeiro, Margarida, Tavares-Correia, João, Godinho, Gonçalo, Alves-Faria, Pedro, Falcão, Manuel, Sousa, Amândio Rocha
• Format: Journal Article
• Language: English
• Published: England BioMed Central 22-08-2024; BMC
• Subjects: Optical coherence tomography angiography; Pars plana vitrectomy; Rhegmatogenous retinal detachment; Superficial vascular plexus; Vessel density; Visual prognosis; Vessel density; Visual prognosis; Pars plana vitrectomy; Superficial vascular plexus; Optical coherence tomography angiography; Rhegmatogenous retinal detachment
• ISSN: 2056-9920; 2056-9920
• DOI: 10.1186/s40942-024-00574-0

To evaluate the visual outcomes and changes in the retinal microcirculation in patients with primary rhegmatogenous retinal detachment (RRD) following successful pars plana vitrectomy (PPV).
Nine macula-on RRD and 23 macula-off RRD eyes were retrospectively evaluated. Clinical data was collected at admission and 3 months after PPV. Optical coherence tomography angiography (OCTA) was performed 3 months after PPV. Superficial vascular plexus data obtained with OCTA was compared between affected and fellow eyes and according to macular involvement. Quantitative measurements of the superficial retinal capillary associated with the preoperative and intraoperative factors were analyzed.
Overall RRD inner vessel densities (IVD), full vessel densities (FVD), inner perfusion densities (IPD) and full perfusion densities (FPD) were significantly and positively correlated with best corrected visual acuity (BCVA)(p = 0.002, p = 0.006, p = 0.009, p = 0.023, respectively). In the macula-off RRD, IVD and FVD were significantly decreased compared with macula-on RRD (p = 0.014 and p = 0.034, respectively) and significantly correlated with a longer duration and larger extension of detachment. Higher differences of IVD and FVD between the fellow and affected eyes were significantly correlated with worse BCVA in the macula-off subgroup.
Macula-off RRD presented worse OCTA superficial vascular parameters compared with the macula-on group and fellow eyes, which were correlated with a poorer visual outcome and exacerbated by a longer duration and larger extension of the detachment. Macula-off RRD causes not only retinal structural damage but also a reduction in retinal perfusion despite successful anatomical repair.