Salivaomics - A promising future in early diagnosis of dental diseases
Human saliva plays an important role in the health of the oral cavity and of the body as a whole. Salivary diagnostics is a dynamic and emerging field in the diagnosis of oral and systemic diseases. Saliva reflects the physiologic state of the body, including emotional, endocrinal, nutritional, and...
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| Published in: | Dental research journal Vol. 11; no. 1; pp. 11 - 15 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
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Iran
Medknow Publications & Media Pvt. Ltd
01-01-2014
Medknow Publications & Media Pvt Ltd Wolters Kluwer Medknow Publications |
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| Abstract | Human saliva plays an important role in the health of the oral cavity and of the body as a whole. Salivary diagnostics is a dynamic and emerging field in the diagnosis of oral and systemic diseases. Saliva reflects the physiologic state of the body, including emotional, endocrinal, nutritional, and metabolic variations. The collection of saliva samples is noninvasive, safe, and inexpensive. Traditional clinical criteria are insufficient for determining sites of active disease, for monitoring the response to therapy, or for measuring the degree of susceptibility to future disease progression. Salivaomics includes five diagnostic alphabets proteins, mRNAs, miRNAs, metabolic compounds, and microbes offering substantial advantages because disease states may be accompanied by detectable changes. Salivaomics, the future of saliva-based techniques for early diagnosis of dental diseases, is promising and may offer a robust alternative for clinicians to use in the near future to make clinical decisions. |
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| AbstractList | Human saliva plays an important role in the health of the oral cavity and of the body as a whole. Salivary diagnostics is a dynamic and emerging field in the diagnosis of oral and systemic diseases. Saliva reflects the physiologic state of the body, including emotional, endocrinal, nutritional, and metabolic variations. The collection of saliva samples is noninvasive, safe, and inexpensive. Traditional clinical criteria are insufficient for determining sites of active disease, for monitoring the response to therapy, or for measuring the degree of susceptibility to future disease progression. Salivaomics includes five diagnostic alphabets proteins, mRNAs, miRNAs, metabolic compounds, and microbes offering substantial advantages because disease states may be accompanied by detectable changes. Salivaomics, the future of saliva-based techniques for early diagnosis of dental diseases, is promising and may offer a robust alternative for clinicians to use in the near future to make clinical decisions. |
| Author | Koneru, Suneetha Tanikonda, Rambabu |
| AuthorAffiliation | 2 Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India 1 Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India |
| AuthorAffiliation_xml | – name: 2 Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India – name: 1 Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24688554$$D View this record in MEDLINE/PubMed |
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| Copyright | Copyright Isfahan University of Medical Sciences Jan 2014 Copyright: © Dental Research Journal 2014 |
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| DOI | 10.4103/1735-3327.127178 |
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| Keywords | saliva Biomarker microbiome transcriptome proteome |
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| References | 23034834 - J Am Dent Assoc. 2012 Oct;143(10 Suppl):19S-24S 19453860 - J Periodontal Res. 2009 Oct;44(5):636-44 17374724 - Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5268-73 10914885 - J Clin Periodontol. 2000 Jul;27(7):453-65 10728975 - J Dent Res. 2000 Feb;79(2):740-7 18804197 - Arch Oral Biol. 2009 Jan;54(1):91-100 17579879 - Int J Legal Med. 2008 Mar;122(2):135-42 20020772 - J Proteome Res. 2010 Apr 5;9(4):1683-93 19878467 - Periodontol 2000. 2009;51:25-37 19824562 - Am J Dent. 2009 Aug;22(4):241-8 21679186 - J Periodontal Res. 2012 Feb;47(1):2-14 19528161 - J Med Microbiol. 2009 Oct;58(Pt 10):1269-74 9529888 - Microbiol Mol Biol Rev. 1998 Mar;62(1):71-109 17435132 - Ann N Y Acad Sci. 2007 Mar;1098:230-51 17329698 - N Engl J Med. 2007 Mar 1;356(9):911-20 20387312 - Biomark Med. 2010 Feb;4(1):171-89 17303835 - Ann N Y Acad Sci. 2007 Mar;1098:7-14 16277573 - J Periodontol. 2005 Nov;76(11 Suppl):2033-41 17652194 - J Dent Res. 2007 Aug;86(8):680-93 19388953 - Periodontol 2000. 2009;50:52-64 15978241 - Dent Clin North Am. 2005 Jul;49(3):551-71, vi 16570465 - J Am Dent Assoc. 2006 Mar;137(3):322-9 21917746 - Adv Dent Res. 2011 Oct;23(4):360-8 12097361 - Crit Rev Oral Biol Med. 2002;13(2):197-212 21917604 - J Dent Res. 2011 Oct;90(10):1153-4 2187975 - J Oral Pathol Med. 1990 Mar;19(3):119-25 16570464 - J Am Dent Assoc. 2006 Mar;137(3):313-21 7118169 - Immunology. 1982 Oct;47(2):383-5 23024320 - J Am Dent Assoc. 2012 Oct;143(10 Suppl):6S-11S 16871209 - Nature. 2006 Jul 27;442(7101):412-8 9080734 - J Dent. 1997 Jan;25(1):3-15 |
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| Title | Salivaomics - A promising future in early diagnosis of dental diseases |
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