Development of a next generation pertussis vaccine: An unbiased biochemical approach to identify novel CD4+ T cell recognized antigens from Bordetella pertussis

Waning acellular pertussis vaccine (aPV) efficacy has brought about the reemergence of pertussis despite global vaccine coverage. Decreasing vaccine efficacy is correlated with the emergence of vaccine escape mutants lacking bacterial antigens expressed in current laboratory strains. Recent work sho...

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Bibliographic Details
Published in:The Journal of immunology (1950) Vol. 210; no. 1_Supplement; pp. 223 - 223.15
Main Authors: Shamseldin, Mohamed Medhat, Hernandez, Gabrielle, Verzani, Eva, Hall, Jesse M, Caution, Kyle J, Carr, Steven A, Deora, Rajendar, Abbelin, Jenn, Dubey, Purnima
Format: Journal Article
Language:English
Published: 01-05-2023
Online Access:Get full text
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