Monitoring protein-metal binding by 19 F NMR - a case study with the New Delhi metallo-β-lactamase 1

F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply F NMR is useful for analysis of different metallated protein states and investigations on equilibrium states in the presence of inhibitors. On...

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Bibliographic Details

Published in:	RSC medicinal chemistry Vol. 11; no. 3; pp. 387 - 391
Main Authors:	Rydzik, Anna M, Brem, Jürgen, Chandler, Shane A, Benesch, Justin L P, Claridge, Timothy D W, Schofield, Christopher J
Format:	Journal Article
Language:	English
Published:	England 30-03-2020
Online Access:	Get full text
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