Antinociceptive activity of transdermal nanostructured surfactant-based systems containing duloxetine hydrochloride

Duloxetine hydrochloride (DLX) is a serotonin and norepinephrine reuptake inhibitor that is effective in the treatment of chronic pain. However, the drug has several adverse reactions and extensive hepatic first-pass effect. This study aimed at developing surfactant-based formulations such as liquid...

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Bibliographic Details

Published in:	Journal of drug delivery science and technology Vol. 101; p. 106166
Main Authors:	Seixas, Karoline Belém, Araujo, Guilherme Rodolfo Souza de, de Oliveira, Alisson Macário, Silveira Filho, Alex José, Leite, Arthur Renato Oliveira Fieto, Napoleão, Thiago Henrique, Sarmento, Victor Hugo Vitorino, Gonsalves, Joyce Kelly Marinheiro da Cunha, Bedor, Danilo César Galindo, Silva, Maria Carolina Silveira Costa, Lira, Ana Amélia Moreira, Leal, Leila Bastos, de Santana, Davi Pereira
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01-11-2024
Subjects:	Antinoceptive Duloxetine Liquid crystals Microemulsion Transdermal Antinoceptive Duloxetine Transdermal Microemulsion Liquid crystals
Online Access:	Get full text
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