Abstract 3665: An EMT gene expression diagnostic predicts resistance to EGFR and MEK-targeted therapies in cell lines and patients

Abstract The epithelial to mesenchymal transition (EMT) in cancer cells results in the acquisition of metastatic properties and may contribute to chemoresistance. Several studies have shown that transition to a mesenchymal phenotype leads to decreased dependence on EGFR-RAS signaling and insensitivi...

Full description

Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 72; no. 8_Supplement; p. 3665
Main Authors:	Eddy, Sean F., Williams, Paul, Tomilo, Mark, Sadis, Seth, Wyngaard, Peter, Vo, Lien, Oades, Kahuku, Kim, Hyunsoo, Wang, Yipeng, Lee, Byung-In, Monforte, Joseph, Rhodes, Daniel
Format:	Journal Article
Language:	English
Published:	15-04-2012
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!