Abstract 5654: Degradation of Bcl-xL by DT2216 is lethal to T-cell acute lymphoblastic leukemia

Abstract Cancer is a multistep process where genomic and epigenomic alterations results in abnormal cellular proliferation and dissemination. This unregulated cellular proliferation can be interrupted through intervention therapy. One such strategy utilizes proteolysis targeting chimeras (PROTACs)....

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 82; no. 12_Supplement; p. 5654
Main Authors:	Jaiswal, Arunima S., Williamson, Elizabeth, Hromas, Robert A., Zhou, Daohong
Format:	Journal Article
Language:	English
Published:	15-06-2022
Online Access:	Get full text
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