Abstract 3962: SGN-LIV1A: a development stage antibody drug-conjugate targeting LIV-1 for the treatment of metastatic breast cancer

LIV-1, also known as SLC39A6 or ZIP6, is a member of the zinc transporter family and was first identified as an estrogen-inducible gene in breast cancer derived cell lines. LIV-1, as a downstream target of STAT3, promotes the epithelial to mesenchymal transition that is important in the malignant pr...

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Bibliographic Details
Published in:Cancer research (Chicago, Ill.) Vol. 73; no. 8_Supplement; p. 3962
Main Authors: Sussman, Django, Smith, Leia M., Anderson, Martha E., Duniho, Steve, Hunter, Joshua H., Kostner, Heather, Miyamoto, Jamie B., Nesterova, Albina, Westendorf, Lori, Van Epps, Heather A., Whiting, Nancy, Benjamin, Dennis R.
Format: Journal Article
Language:English
Published: 15-04-2013
Online Access:Get full text
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