The seminal microflora does not alter in patients with premature ejaculation

• Published in: Journal of sexual medicine Vol. 19; no. 11; pp. S76 - S77
• Main Authors: Yildirim, Dr. Omer, Gultekin, Dr. Mehmet H., Aygun, Prof. Gokhan, Ozkara, Prof. Hamdi, Akkus, Prof. Emre
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-11-2022
• ISSN: 1743-6095; 1743-6109
• DOI: 10.1016/j.jsxm.2022.10.014

Although premature ejaculation (PE) is one of the most common male sexual dysfunctions, the etiology is still to be revealed. In this study, the relationship between PE and seminal microflora was investigated.
A total of 136 males, consisting of 66 primary or secondary PE patients and 70 controls (no PE) were included in the study. Sociodemographic data and estimated intravaginal ejaculation latency time (eIELT) of all the participants were recorded. Charlson comorbidity index (CCI), total testosterone (TT), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), thyroid-stimulating hormone (TSH) were all assessed. Premature ejaculation diagnostic tool (PEDT), the International Index of erectile function-5 (IIEF-5), the Chronic prostatitis symptom index (NIH-CPSI) were filled in the cases. Urine and semen cultures were performed. The count of leukocytes in the semen was evaluated.
The mean age in the PE group was 38.27 ± 8.47 years, while it was 33.66 ± 8.04 years in the control group (p<0.05). The mean eIELT was substantially lower in the PE group than in the control group (p<0.001). PEDT and NIH-CPSI scores were found to be significantly higher in the PE group (respectively p<0.001; p<0.05). The IIEF-5 score was markedly lower in the PE group than in the control group (p<0.001). The values of CCI, TT, LH, FSH, PRL, and TSH in the two groups were comparable (p<0.05). The number of leukocytes in the semen, as well as bacterial growth in urine and semen cultures, were not different across the groups (p>0.05).
In terms of seminal microflora, there was no difference between the PE patients and the control group. However, considering the recognized association between chronic prostatitis and PE, it is observed that further studies into the topic with more advanced research techniques in larger populations are needed.
The all authors declare no conflict of interest.