AGGRESSIVE PRIMARY INTRAOSSEOUS CARCINOMA AMELOBLASTOMA-LIKE INVOLVING ANTERIOR REGION AND MANDIBULAR BODY: CASE REPORT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 134; no. 3; p. e148
• Main Authors: Da Costa Mendes, Tassia Caroline, Deip, Luis Felipe Alves, De Albuquerque, Gustavo Cavalcanti, Filho, Raimundo Monteiro Maia, Abrahim, Naíza Menezes Medeiros, Libório-Kimura, Tatiana Nayara, Câmara, Jeconias
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01-09-2022
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2022.01.360

Primary intraosseous carcinoma of the jaw is a rare malignant tumor with poor prognosis. A 66-year-old male smoker presented with swelling in the anterior region and right body mandibular, with extraoral fistula and palpable cervical lymph nodes. Intraoral examination evidenced an ulceration with a hard consistency. Panoramic radiograph and computed tomography revealed a large lesion with bone destruction in the region. After incisional biopsy, microscopic examination revealed a proliferation of epithelial cells sometimes similar to squamous cells, forming keratin pearls, or similar to the odontogenic epithelium, arranged in nests and islands of basaloid cells with peripheral palisading. Atypia, pleomorphism, and mitoses were observed, leading to the diagnosis of primary intraosseous carcinoma ameloblastoma-like. The patient underwent mandibulectomy, partial glossectomy, and removal of the floor of the mouth muscles. Follow-up is still being carried out and 1 month after surgery the patient is in stable condition without pain.