Abstract 14309: A Novel Fibroblast Activation Inhibitor, NM922, Attenuates Maladaptive Fibrotic Remodeling to Preserve Cardiac Function Following the Onset of Heart Failure

BackgroundCardiac fibroblasts are critical mediators of fibrotic remodeling in the failing heart. These maladaptive structural changes can worsen cardiac function accelerating the progression to decompensated heart failure (HF). We investigated the effects of a novel inhibitor of the conversion of n...

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Bibliographic Details

Published in:	Circulation (New York, N.Y.) Vol. 132; no. Suppl_3 Suppl 3; p. A14309
Main Authors:	Bradley, Jessica M, Ziblich, Craig M, Islam, Kazi N, Rushing, Amanda M, Polhemus, David J, Corral, Laura G, Sullivan, Robert W, Fung, Leah, Chan, Kyle W, Swindlehurst, Cathy A, Lefer, David J
Format:	Journal Article
Language:	English
Published:	by the American College of Cardiology Foundation and the American Heart Association, Inc 10-11-2015
Online Access:	Get full text
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