HEMATOPOIETIC STEM CELL GENE THERAPY AS A NOVEL THERAPEUTIC APPROACH FOR SEVERE CROHN’S DISEASE ASSOCIATED WITH NOD2-DEFICIENCY

Pathogenic variants of the NOD2 (nucleotide-binding oligomerization domain containing protein 2) gene demonstrate the strongest genetic association to Crohn’s inflammatory bowel disease (CD). Mounting evidence links NOD2 deficiency with poor clinical outcome, particularly in pediatric and early onse...

Full description

Bibliographic Details

Published in:	Inflammatory bowel diseases Vol. 30; no. Supplement_1; p. S42
Main Authors:	Enjalbert, Florence, Masdeu, Maria Del Mar, Zabinski, Tomasz, Narean, Janakan Sam, Whiting, Christopher, Elavazhagan, Saranya, Luiz, Ana, Du, Lily, Pennucci, Valentina, Cattoni, Marina, Heal, Paul, Recchi, Chiara, Gaspar, Bobby, Mavilio, Fulvio, Sagoo, Pervinder
Format:	Journal Article
Language:	English
Published:	25-01-2024
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!