Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

Microbiome community typing analyses have recently identified the Bacteroides 2 (Bact2) enterotype, an intestinal microbiota configuration that is associated with systemic inflammation and has a high prevalence in loose stools in humans 1 , 2 . Bact2 is characterized by a high proportion of Bacteroi...

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Published in:	Nature (London) Vol. 581; no. 7808; pp. 310 - 315
Main Authors:	Vieira-Silva, Sara, Falony, Gwen, Belda, Eugeni, Nielsen, Trine, Aron-Wisnewsky, Judith, Chakaroun, Rima, Forslund, Sofia K., Assmann, Karen, Valles-Colomer, Mireia, Nguyen, Thi Thuy Duyen, Proost, Sebastian, Prifti, Edi, Tremaroli, Valentina, Pons, Nicolas, Le Chatelier, Emmanuelle, Andreelli, Fabrizio, Bastard, Jean-Phillippe, Coelho, Luis Pedro, Galleron, Nathalie, Hansen, Tue H., Hulot, Jean-Sébastien, Lewinter, Christian, Pedersen, Helle K., Quinquis, Benoit, Rouault, Christine, Roume, Hugo, Salem, Joe-Elie, Søndertoft, Nadja B., Touch, Sothea, Dumas, Marc-Emmanuel, Ehrlich, Stanislav Dusko, Galan, Pilar, Gøtze, Jens P., Hansen, Torben, Holst, Jens J., Køber, Lars, Letunic, Ivica, Nielsen, Jens, Oppert, Jean-Michel, Stumvoll, Michael, Vestergaard, Henrik, Zucker, Jean-Daniel, Bork, Peer, Pedersen, Oluf, Bäckhed, Fredrik, Clément, Karine, Raes, Jeroen
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-05-2020 Nature Publishing Group
Subjects:	49/23 49/31 631/326/2565/107 631/326/2565/2134 631/326/2565/2142 692/699/2743/2037 692/699/2743/393 Analysis bacterial count bacterium bacterium identification Bacteroides Bacteroides - isolation & purification Bioinformatics and Systems Biology Bioinformatik och systembiologi body mass Body mass index Body size Body weight Cardiovascular diseases Causes of cell cell density Cohort Studies comorbidity Constellations Control correlation analysis Cross-Sectional Studies Digestive system disease prevalence Diseases Distribution Dosage and administration Drug therapy Dysbacteriosis Dysbiosis Dysbiosis - epidemiology Dysbiosis - prevention & control Endocrinology and Diabetes Endokrinologi och diabetes Faecalibacterium Faecalibacterium - isolation & purification Feces - microbiology feces analysis Female Flora Gastrointestinal Microbiome - drug effects Gastrointestinal tract human Humanities and Social Sciences Humans hydroxymethylglutaryl coenzyme A reductase inhibitor Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use hypercholesterolemia Inflammation inflammatory bowel disease Inflammatory bowel diseases Inflammatory Bowel Diseases - microbiology Intestinal microflora Intestine intestine flora Life Sciences Load Male metabolic disorder Metabolic syndrome metagenome microbial community Microbiomes Microbiota Microbiota (Symbiotic organisms) Microorganisms multidisciplinary nonhuman Obesity Obesity - microbiology Overweight Overweight persons prediction Prevalence Prevalence studies (Epidemiology) priority journal quantitative analysis Science Science (multidisciplinary) species diversity Statins Triglycerides Belgium
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