Binding of recombinant PrP c to human plasminogen: Kinetic and thermodynamic study using a resonant mirror biosensor

Transmissible spongiform encephalopathies are a class of sporadic, genetic and transmissible neurodegenerative diseases that affect both humans and animals. Propagation of these diseases is thought to be due to the misfolding of a neuronal glyco‐protein, PrP c , into a pathological insoluble conform...

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Bibliographic Details
Published in:Proteins, structure, function, and bioinformatics Vol. 58; no. 3; pp. 728 - 734
Main Authors: Cuccioloni, Massimiliano, Amici, Manila, Eleuteri, Anna Maria, Biagetti, Massimo, Barocci, Simone, Angeletti, Mauro
Format: Journal Article
Language:English
Published: 15-02-2005
Online Access:Get full text
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