Prognostic significance of erythropoietin in pancreatic adenocarcinoma

Erythropoietin (Epo) administration has been reported to have tumor-promoting effects in anemic cancer patients. We investigated the prognostic impact of endogenous Epo in patients with pancreatic ductal adenocarcinoma (PDAC). The clinico-pathological relevance of hemoglobin (Hb, n = 150), serum Epo...

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Bibliographic Details
Published in:	PloS one Vol. 6; no. 8; p. e23151
Main Authors:	Welsch, Thilo, Zschäbitz, Stefanie, Becker, Verena, Giese, Thomas, Bergmann, Frank, Hinz, Ulf, Keleg, Shereen, Heller, Anette, Sipos, Bence, Klingmüller, Ursula, Büchler, Markus W, Werner, Jens, Giese, Nathalia A
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01-08-2011 Public Library of Science (PLoS)
Subjects:	1-Phosphatidylinositol 3-kinase Adenocarcinoma Adult Aged AKT protein Analysis Anemia Autoantibodies - immunology Base Sequence Biology Blotting, Western Breast cancer Cancer metastasis Cancer patients Capillaries Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - physiopathology Chemoresistance Chemotherapy Clinical trials Cytokines Cytotoxicity DNA Primers Erythropoietin Erythropoietin - genetics Erythropoietin - physiology Female Flow Cytometry Genes Hemoglobin Hemoglobins Hepatocytes Hospitals Humans Immunohistochemistry Immunoprecipitation Liver Liver cancer Lung cancer Male Medical research Medicine Metastases Middle Aged Pancreas Pancreatic cancer Pancreatic Neoplasms - pathology Pancreatic Neoplasms - physiopathology Pancreatitis Pathology Patients Prognosis Proteins Real-Time Polymerase Chain Reaction Receptors, Erythropoietin - genetics Receptors, Erythropoietin - immunology RNA, Messenger - genetics Signal transduction Signaling Stem cells Surgery Tumor cells Germany
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