Discovery of a Rapidly Metabolized, Long-Acting β 2 Adrenergic Receptor Agonist with a Short Onset Time Incorporating a Sulfone Group Suitable for Once-Daily Dosing

Discovery of a Rapidly Metabolized, Long-Acting β 2 Adrenergic Receptor Agonist with a Short Onset Time Incorporating a Sulfone Group Suitable for Once-Daily Dosing

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Bibliographic Details
Published in:Journal of medicinal chemistry Vol. 57; no. 1; pp. 159 - 170
Main Authors: Procopiou, Panayiotis A., Barrett, Victoria J., Biggadike, Keith, Butchers, Peter R., Craven, Andrew, Ford, Alison J., Guntrip, Stephen B., Holmes, Duncan S., Hughes, Sara C., Jones, Anne E., Looker, Brian E., Mutch, Peter J., Ruston, Mark, Needham, Deborah, Smith, Claire E.
Format: Journal Article
Language:English
Published: 09-01-2014
Online Access:Get full text
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Description
ISSN:0022-2623
1520-4804
DOI:10.1021/jm401532g