Differential regulation and impact of fucosyltransferase VII and core 2 β1,6‐ N ‐acetyl‐glycosaminyltransferase for generation of E ‐selectin and P ‐selectin ligands in murine CD 4 + T cells

Ligands for E ‐selectin and P ‐selectin ( E ‐lig and P ‐lig) are induced on CD 4 + T cells upon differentiation into effector T cells. Glycosyltransferases, especially α 1,3‐fucosyltransferase VII ( F uc T ‐VII) and core 2 β1,6‐ N ‐acetyl‐glycosaminyltransferase I ( C 2 G lc NA c T ‐I), are critical...

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Bibliographic Details
Published in:Immunology Vol. 137; no. 4; pp. 294 - 304
Main Authors: Schroeter, Micha F., Ratsch, Boris A., Lehmann, Jeanette, Baumgrass, Ria, Hamann, Alf, Syrbe, Uta
Format: Journal Article
Language:English
Published: 01-12-2012
Online Access:Get full text
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