Brønsted Acid-Catalyzed, Asymmetric Allenoate Claisen Reaction

An auxiliary-based protocol is described for an asymmetric allenoate Claisen rearrangement. Silicated tosic acid (10 mol %) was used as an inexpensive, user-friendly catalyst. Stereochemical analysis revealed a preferential attack at the si face of prostereogenic olefin. The amine auxiliary was read...

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Bibliographic Details

Published in:	Journal of organic chemistry
Main Authors:	Hamilton, Rachael E., Berkley, Ellen A., Laufer, Iain K., Ruos, Madeline E., Smith, Brandon, Dahi, Anthony N., Gallagher, Timothy J., Justo, Vanessa, Warner, Flannery, Wenzel, Anna G.
Format:	Journal Article
Language:	English
Published:	26-11-2024
Online Access:	Get full text
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