Absence of detectable replication of human bocavirus species 2 in respiratory tract

• Published in: Emerging infectious diseases Vol. 15; no. 9; pp. 1503 - 1505
• Main Authors: Chieochansin, Thaweesak, Kapoor, Amit, Delwart, Eric, Poovorawan, Yong, Simmonds, Peter
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01-09-2009; Centers for Disease Control and Prevention
• Subjects: Adult; Age Distribution; Bocavirus - classification; Bocavirus - genetics; Bocavirus - isolation & purification; Causes of; Child; Child, Preschool; Diagnosis; diarrhea; Diarrhea - epidemiology; Diarrhea - virology; Dispatch; DNA Primers; DNA, Viral - analysis; DNA, Viral - isolation & purification; Feces - virology; Female; Health aspects; Human bocavirus; Humans; Infant; Male; Parvoviridae Infections - epidemiology; Parvoviridae Infections - virology; parvovirus; PCR; Polymerase chain reaction; respiratory infections; Respiratory System - virology; Respiratory tract diseases; Respiratory Tract Infections - epidemiology; Respiratory Tract Infections - virology; Species Specificity; Thailand - epidemiology; United Kingdom - epidemiology; Virus Replication - physiology; Viruses; United Kingdom
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid1509.090394

Human bocavirus (HBoV) commonly infects young children and is associated with respiratory disease; disease associations of the divergent HBoV-2 species are unknown. Frequent HBoV-2 detection in fecal samples indicated widespread circulation in the United Kingdom and Thailand, but its lack of detection among 6,524 respiratory samples indicates likely differences from HBoV-1 in tropism/pathogenesis.