Validity and reliability of a new tool to evaluate handwriting difficulties in Parkinson's disease

• Published in: PloS one Vol. 12; no. 3; p. e0173157
• Main Authors: Nackaerts, Evelien, Heremans, Elke, Smits-Engelsman, Bouwien C M, Broeder, Sanne, Vandenberghe, Wim, Bergmans, Bruno, Nieuwboer, Alice
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 02-03-2017; Public Library of Science (PLoS)
• Subjects: Abnormalities; Analysis; Biology and Life Sciences; Case-Control Studies; Correlation; Correlation analysis; Correlation coefficient; Correlation coefficients; Cross-Sectional Studies; Female; Handwriting; Humans; Male; Medical protocols; Medical research; Medicine and Health Sciences; Motor skill; Motor task performance; Movement disorders; Neurodegenerative diseases; Neurology; Parkinson disease; Parkinson Disease - physiopathology; Parkinson's disease; Parkinsons disease; Patients; Rehabilitation; Reliability analysis; Research and Analysis Methods; Screening; Skills; Systematic review; Validity
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0173157

Handwriting in Parkinson's disease (PD) features specific abnormalities which are difficult to assess in clinical practice since no specific tool for evaluation of spontaneous movement is currently available.
This study aims to validate the 'Systematic Screening of Handwriting Difficulties' (SOS-test) in patients with PD.
Handwriting performance of 87 patients and 26 healthy age-matched controls was examined using the SOS-test. Sixty-seven patients were tested a second time within a period of one month. Participants were asked to copy as much as possible of a text within 5 minutes with the instruction to write as neatly and quickly as in daily life. Writing speed (letters in 5 minutes), size (mm) and quality of handwriting were compared. Correlation analysis was performed between SOS outcomes and other fine motor skill measurements and disease characteristics. Intrarater, interrater and test-retest reliability were assessed using the intraclass correlation coefficient (ICC) and Spearman correlation coefficient.
Patients with PD had a smaller (p = 0.043) and slower (p<0.001) handwriting and showed worse writing quality (p = 0.031) compared to controls. The outcomes of the SOS-test significantly correlated with fine motor skill performance and disease duration and severity. Furthermore, the test showed excellent intrarater, interrater and test-retest reliability (ICC > 0.769 for both groups).
The SOS-test is a short and effective tool to detect handwriting problems in PD with excellent reliability. It can therefore be recommended as a clinical instrument for standardized screening of handwriting deficits in PD.