Hydrogel-Based Ultra-moisturizing Cream Formulation for Skin Hydration and Enhanced Dermal Drug Delivery

To develop an external vehicle for skin hydration and enhanced dermal drug delivery, a hydrogel-based ultra-moisturizing cream (HUMC) was successfully formulated with carbopol 934P, urea, Tinocare GL, grape seed oil, and other excipients. The HUMC showed plastic flow behavior due to a gel structure...

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Bibliographic Details
Published in:	Biological & pharmaceutical bulletin Vol. 37; no. 10; pp. 1674 - 1682
Main Authors:	Lee, Sang Gon, Kim, Sung Rae, Cho, Hye In, Kang, Mean Hyung, Yeom, Dong Woo, Lee, Seo Hyun, Lee, Sangkil, Choi, Young Wook
Format:	Journal Article
Language:	English
Published:	Japan The Pharmaceutical Society of Japan 01-10-2014 Pharmaceutical Society of Japan Japan Science and Technology Agency
Subjects:	Administration, Cutaneous Animals Drug Delivery Systems - methods Emollients - administration & dosage Emollients - metabolism Hydrogel, Polyethylene Glycol Dimethacrylate - administration & dosage Hydrogel, Polyethylene Glycol Dimethacrylate - metabolism hydrogel-based cream Hypodermoclysis - methods Male Mice Mice, Hairless moisturizer Organ Culture Techniques Skin Absorption - drug effects Skin Absorption - physiology Skin Cream - administration & dosage Skin Cream - metabolism skin distribution skin hydration skin permeation topical delivery
Online Access:	Get full text
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