A Fast and Activatable Cross-Linking Strategy for Hydrogel Formation

A Fast and Activatable Cross-Linking Strategy for Hydrogel Formation

Strain‐promoted oxidation‐controlled cyclo­octyne‐1,2‐quinone cycloaddition (SPOCQ) is a fast and activatable cross‐linking strategy for hydrogel formation. Gelation is induced by oxidation, which is performed both chemically using sodium periodate and enzymatically using mushroom tyrosinase. Due to...

Full description

Saved in:
Bibliographic Details
Published in:Advanced materials (Weinheim) Vol. 27; no. 7; pp. 1235 - 1240
Main Authors: Jonker, Anika M., Borrmann, Annika, van Eck, Ernst R. H., van Delft, Floris L., Löwik, Dennis W. P. M., van Hest, Jan C. M.
Format: Journal Article
Language:English
Published: Germany Blackwell Publishing Ltd 18-02-2015
Subjects:
activatable
cross-linking
Crosslinking
Cycloaddition
Formations
hydrogel
Hydrogels
Mushrooms
oxidation
Sodium
Strategy
Tyrosinase
oxidation
cross-linking
hydrogel
activatable
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Strain‐promoted oxidation‐controlled cyclo­octyne‐1,2‐quinone cycloaddition (SPOCQ) is a fast and activatable cross‐linking strategy for hydrogel formation. Gelation is induced by oxidation, which is performed both chemically using sodium periodate and enzymatically using mushroom tyrosinase. Due to the fast reaction kinetics, SPOCQ‐formed hydrogels can be functionalized in one‐pot with an azido‐containing moiety using SPAAC cross‐linking.
Bibliography:VICI - No. 700.10.442
Ministry of Education, Culture and Science - No. 024.001.035
istex:3BB3E4116CA79857407241CC08BECD531ED5A775
ArticleID:ADMA201404448
ark:/67375/WNG-58FHL4B8-D
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201404448