Characterising temporal trends in asymptomatic Plasmodium infections and transporter polymorphisms during transition from high to low transmission in Zanzibar, 2005–2013

•Declining, but persistent, reservoir of low-density malaria in Zanzibar between 2005 and 2013.•Decreasing MOI after 2005, but genetic diversity of P. falciparum remained high.•Declining prevalence of AQ resistance associated pfcrt 76T and pfmdr1 86Y despite wide scale use of ASAQ.•AQ resistance ass...

Full description

Saved in:

Bibliographic Details
Published in:	Infection, genetics and evolution Vol. 33; pp. 110 - 117
Main Authors:	Morris, Ulrika, Xu, Weiping, Msellem, Mwinyi I., Schwartz, Alanna, Abass, Ali, Shakely, Delér, Cook, Jackie, Bhattarai, Achuyt, Petzold, Max, Greenhouse, Bryan, Ali, Abdullah S., Björkman, Anders, Fröberg, Gabrielle, Mårtensson, Andreas
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-07-2015
Subjects:	Adolescent Adult Antimalarial drug resistance Antimalarial drug resistance markers ARTEMETHER-LUMEFANTRINE ARTESUNATE-AMODIAQUINE Asymptomatic Asymptomatic Infections CARRIAGE Child Child, Preschool COMBINATION THERAPY Cross-Sectional Studies FALCIPARUM DRUG-RESISTANCE Female Genotype Humans IN-VITRO Infant Infectious Diseases Infectious Medicine Infektionsmedicin Low transmission MALARIA PARASITE Malaria, Falciparum - epidemiology Malaria, Falciparum - parasitology Male Medicin och hälsovetenskap Membrane Transport Proteins - genetics Middle Aged Molecular surveillance Parasite Load PFMDR1 GENES Plasmodium Plasmodium falciparum - classification Plasmodium falciparum - genetics POLYMERASE-CHAIN-REACTION Polymorphism, Single Nucleotide Prevalence Protozoan Proteins - genetics RAPID DIAGNOSTIC-TESTS Tanzania - epidemiology Young Adult Tanzania Plasmodium Low transmission Molecular surveillance Asymptomatic Antimalarial drug resistance markers
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!