The degree of global DNA hypomethylation in peripheral blood correlates with that in matched tumor tissues in several neoplasia

There are no good blood and serum biomarkers for detection, follow up, or prognosis of brain tumors. However, they are needed for more detailed tumor classification, better prognosis estimation and selection of an efficient therapeutic strategy. The aim of this study was to use the epigenetic change...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 3; p. e92599
Main Authors:	Barciszewska, Anna-Maria, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 20-03-2014 Public Library of Science (PLoS)
Subjects:	5-Methylcytosine - blood Adult Aged Aged, 80 and over Analysis Biology and Life Sciences Biomarkers Biomarkers, Tumor Blood Brain Brain cancer Brain Neoplasms - blood Brain Neoplasms - genetics Brain tumors Breast cancer Cancer Cancer research Chromatography Colon Colon cancer Colorectal cancer Deoxyribonucleic acid Development and progression Diagnosis DNA DNA Methylation Epigenesis, Genetic Epigenetic inheritance Epigenetics Female Health aspects Humans Male Malignancy Medicine and Health Sciences Middle Aged Neoplasia Neoplasms Neoplasms - blood Neoplasms - genetics Patients Peripheral blood Physical Sciences Prognosis Pyrimidines Quality Thin layer chromatography Tissues Tumors Young Adult
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