Transmission electron microscopy reveals distinct macrophage- and tick cell-specific morphological stages of Ehrlichia chaffeensis

Ehrlichia chaffeensis is an emerging tick-borne rickettsial pathogen responsible for human monocytic ehrlichiosis. Despite the induction of an active host immune response, the pathogen has evolved to persist in its vertebrate and tick hosts. Understanding how the organism progresses in tick and vert...

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Bibliographic Details
Published in:	PloS one Vol. 7; no. 5; p. e36749
Main Authors:	Dedonder, Sarah E, Cheng, Chuanmin, Willard, Lloyd H, Boyle, Daniel L, Ganta, Roman R
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 15-05-2012 Public Library of Science (PLoS)
Subjects:	Adaptation Anaplasma phagocytophilum Animals Bacteria Biology Biosynthesis Blotting, Western Chlamydia Confocal Confocal microscopy Disease transmission Ehrlichia Ehrlichia canis Ehrlichia chaffeensis Ehrlichia chaffeensis - growth & development Ehrlichia chaffeensis - ultrastructure Ehrlichiosis Electron microscopy Exocytosis Fission Granulocytes Human behavior Immune response Immune system Infections Localization Lysis Macrophages Macrophages - microbiology Microscopy, Confocal Microscopy, Electron, Transmission - methods Monocytes Morphology Nuclei Nuclei (cytology) Organisms Pathogens Proteins Replication Ticks - microbiology Transmission electron microscopy Veterinary colleges Veterinary medicine Kansas
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