Central nervous system infection in the intensive care unit: Development and validation of a multi-parameter diagnostic prediction tool to identify suspected patients

Central nervous system infections (CNSI) are diseases with high morbidity and mortality, and their diagnosis in the intensive care environment can be challenging. Objective: To develop and validate a diagnostic model to quickly screen intensive care patients with suspected CNSI using readily availab...

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Bibliographic Details
Published in:	PloS one Vol. 16; no. 11; p. e0260551
Main Authors:	Andrade, Hugo Boechat, Ferreira da Silva, Ivan Rocha, Sim, Justin Lee, Mello-Neto, José Henrique, Theodoro, Pedro Henrique Nascimento, Torres da Silva, Mayara Secco, Varela, Margareth Catoia, Ramos, Grazielle Viana, Ramos da Silva, Aline, Bozza, Fernando Augusto, Soares, Jesus, Belay, Ermias D, Sejvar, James J, Cerbino-Neto, José, Japiassú, André Miguel
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 29-11-2021 Public Library of Science (PLoS)
Subjects:	Adult Aged Biology and Life Sciences Brain research Brazil Care and treatment Central nervous system Central nervous system diseases Central Nervous System Infections - diagnosis Cerebrospinal fluid Chicago Confidence intervals Convulsions & seizures Critical Care Critical care medicine Critically ill Data collection Diagnosis Disease control Disease prevention Education Encephalitis Female Fever Glasgow Coma Scale Health risks Health surveillance HIV Human immunodeficiency virus Humans Immune system Infections Infectious diseases Intensive care Intensive Care Units Laboratories Leukocytes Logistic Models Male Medical diagnosis Medical imaging Medical records Medicine and Health Sciences Meningitis Methods Middle Aged Morbidity Multivariate Analysis Nervous system Parameter identification Pathogens Pathology Patients Prediction models Prognosis Public health Regression analysis Regression models Retrospective Studies Risk factors ROC Curve Seizures Statistical analysis Zoonoses Brazil Chicago Atlanta Georgia Rio de Janeiro Brazil Chicago Illinois United States > US
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