Periostin secreted by activated fibroblasts in idiopathic pulmonary fibrosis promotes tumorigenesis of non-small cell lung cancer

Non-small cell lung cancer (NSCLC) patients with idiopathic pulmonary fibrosis (IPF) show poor prognosis. Periostin is an extracellular matrix protein highly expressed in the lung tissues of IPF. This study aimed to investigate the possibility that periostin secreted by fibroblasts derived from IPF...

Full description

Saved in:

Bibliographic Details
Published in:	Scientific reports Vol. 11; no. 1; pp. 21114 - 15
Main Authors:	Yamato, Hiroyuki, Kimura, Kenji, Fukui, Eriko, Kanou, Takashi, Ose, Naoko, Funaki, Soichiro, Minami, Masato, Shintani, Yasushi
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 26-10-2021 Nature Publishing Group Nature Portfolio
Subjects:	631/67/1612 631/67/327 A549 Cells Carcinogenesis - genetics Carcinogenesis - metabolism Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Cell Adhesion Molecules - biosynthesis Cell Adhesion Molecules - genetics Cell proliferation Extracellular matrix Female Fibroblasts Fibroblasts - metabolism Fibrosis Humanities and Social Sciences Humans Idiopathic Pulmonary Fibrosis - genetics Idiopathic Pulmonary Fibrosis - metabolism Lung cancer Lung diseases Lung Neoplasms - genetics Lung Neoplasms - metabolism Male Matrix protein multidisciplinary Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Non-small cell lung carcinoma Pulmonary fibrosis Science Science (multidisciplinary) Small cell lung carcinoma Tumorigenesis
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!