Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February-March 2021

• Published in: Emerging infectious diseases Vol. 27; no. 8; pp. 2169 - 2173
• Main Authors: Tober-Lau, Pinkus, Schwarz, Tatjana, Hillus, David, Spieckermann, Jana, Helbig, Elisa T, Lippert, Lena J, Thibeault, Charlotte, Koch, Willi, Bergfeld, Leon, Niemeyer, Daniela, Mühlemann, Barbara, Conrad, Claudia, Kasper, Stefanie, Münn, Friederike, Kunitz, Frank, Jones, Terry C, Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Kurth, Florian, Corman, Victor M
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01-08-2021; Centers for Disease Control and Prevention
• Subjects: Berlin; Cell culture; Control; Coronaviruses; COVID-19; COVID-19 vaccines; Demographic aspects; Disease Outbreaks; Disease transmission; Dispatch; Epidemics; Fatalities; Germany; Germany - epidemiology; Humans; immunity; Infections; Infectious diseases; Long term health care; Long-Term Care; Long-term care facilities; Management; mRNA; Older people; outbreak; Outbreaks; Oxygen therapy; Patient outcomes; Patients; phylogeny; Risk factors; Safety and security measures; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; T cell; Vaccination; vaccine; Berlin; Germany; Berlin Germany; viruses; antibody; Berlin; T cell; zoonoses; mRNA; immunity; respiratory infections; COVID-19; B cell; SARS-CoV-2; vaccine; severe acute respiratory syndrome coronavirus 2; outbreak; phylogeny; coronavirus disease; Germany
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2708.210887

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.