Placebos without deception: a randomized controlled trial in irritable bowel syndrome

Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception. We tested whether open-label placebo (non-deceptive and non-concealed administration) is superior to a no-treatment control with matched patie...

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Bibliographic Details
Published in:	PloS one Vol. 5; no. 12; p. e15591
Main Authors:	Kaptchuk, Ted J, Friedlander, Elizabeth, Kelley, John M, Sanchez, M Norma, Kokkotou, Efi, Singer, Joyce P, Kowalczykowski, Magda, Miller, Franklin G, Kirsch, Irving, Lembo, Anthony J
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 22-12-2010 Public Library of Science (PLoS)
Subjects:	Adult Archives & records Attention Deficit Hyperactivity Disorder Care and treatment Child care Clinical medicine Clinical trials Constipation Control methods Deception Ethics Female History of medicine Humans Informed consent Intestine Irritable bowel syndrome Irritable Bowel Syndrome - drug therapy Male Medical personnel Medical schools Medicine Middle Aged Patient Satisfaction Patients Physicians Pills Placebo effect Placebos Qualitative research Quality of life Randomization Sugar Time Factors Treatment Outcome Womens health United States > US Massachusetts
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