Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis

• Published in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 18; no. 8; pp. 847 - 854
• Main Authors: Dominguez-Munoz, J. Enrique, Drewes, Asbjørn M., Lindkvist, Björn, Ewald, Nils, Czakó, László, Rosendahl, Jonas, Löhr, J. Matthias, Löhr, Matthias, Besselink, Marc, Mayerle, Julia, Lerch, Markus M., Akisik, Fatih, Kartalis, Nikolaos, Manfredi, Riccardo, Iglesias-Garcia, Julio, Haas, Stephan L., Keller, Jutta, Boermeester, Marja A., Werner, Jens, Dumonceau, Jean-Marc, Fockens, Paul, Drewes, Asbjørn, Cheyan, Güralp O., Drenth, Joost P., Hardt, Philip, de Madaria, Enrique, Gheorghe, Christian, Lindgren, Fredrik, Schneider, Alexander, Witt, Heiko, Bollen, Thomas, Boraschi, Piero, Frøkjær, Jens B., Rudolf, Sasa, Bruno, Marco, Dimcevski, Georg, Giovannini, Marc, Pukitis, Aldis, Petrone, Mariachiara, Oppong, Kofi, Ammori, Basil, Friess, Helmut, Izbiki, Jakob R., Ganeh, Paula, Salvia, Roberto, Sauvanet, Alain, Barbu, Sorin, Lyadov, Vladimir, Deprez, Pierre, Gubergrits, Natalja, Okhlobystiy, Alexey V., Arvanitakis, Marianna, Costamagna, Guido, Pap, Akos, Andersson, Roland, Hauge, Truls, McKay, Colin, Pukitis, Aldos, Regnér, Sara, Dite´, Peter, Olesen, Søren S., Duggan, Sinead, Hopper, Andrew, Phillips, Mary, Shvets, Oleg, Vujasinovic, Miroslav, Czako, Laszlo, Piemonti, Lorenzo, Kocher, Hemant, Rebours, Vinciane, Stimac, Davor, Hegyi, Peter
• Format: Journal Article
• Language: English
• Published: Switzerland Elsevier B.V 01-12-2018; Elsevier Limited
• Subjects: Abdomen; Agreements; Alcohol; analgesia; analgesic agent; artificial embolization; calcification; Chronic pancreatitis; classification; Clinical Medicine; consensus; conservative treatment; Cysts; Development and evaluation; Development and evaluation (GRADE); Diabetes; Diabetes mellitus; Diagnosis; dilated pancreatic duct; disease; Disease management; echography; Endoscopic therapy; endoscopic ultrasonography; Endoscopy; enzyme replacement; Etiology; European; evidence based practice; Evidence-Based Medicine; exocrine pancreatic insufficiency; Exocrine Pancreatic Insufficiency - diagnosis; Exocrine Pancreatic Insufficiency - surgery; Exocrine Pancreatic Insufficiency - therapy; extracorporeal shock wave lithotripsy; false aneurysm; Family medical history; Gastroenterologi; gastroenterologist; Gastroenterology; Gastroenterology & Hepatology; Gastroenterology and Hepatology; grade; Grading of recommendations assessment; Guidelines; Health Care Service and Management, Health Policy and Services and Health Economy; Health Sciences; Humans; Hypoglycemia; Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi; Hälsovetenskap; insufficiency; Insulin; Klinisk medicin; Literature reviews; magnetic resonance cholangiopancreatography; Malnutrition; management; Medical and Health Sciences; Medical diagnosis; Medical imaging; Medicin och hälsovetenskap; NMR; Nuclear magnetic resonance; nuclear magnetic resonance imaging; nutrition; nutritional assessment; Pain; Pain - etiology; Pain Management; Pancreas; pancreas disease; pancreas enzyme; pancreas function test; pancreas pseudocyst; pancreas surgery; pancreatic duct; Pancreatic exocrine insufficiency; Pancreatic Pseudocyst - therapy; Pancreatitis; Pancreatitis, Chronic - diagnosis; Pancreatitis, Chronic - surgery; Pancreatitis, Chronic - therapy; pancreatogenic diabetes; practice guideline; Pseudocyst; quality; Quality of life; Questionnaires; Smoking cessation; strength; Ultrasonic imaging; CPRD; PRSS1; FE-1; Pseudocyst; MRI; Guidelines; QoL; PERT; Pain; 13C-MTG-BT; US; Pancreatic exocrine insufficiency; CPA1; EUS; SPINK1; Chronic pancreatitis; Diabetes mellitus; Development and evaluation (GRADE); CEL; CP; DPPHR; Quality of life; HaPanEU; CT; Endoscopic therapy; Grading of recommendations assessment; PD; PEI; MRCP; UEG; GRADE; CTRC; CFTR; CFA
• ISSN: 1424-3903; 1424-3911; 1424-3911
• DOI: 10.1016/j.pan.2018.09.016

In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach.
Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefined clinical questions are summarised. Recommendations are graded using the Grading of Recommendations Assessment, Development and Evaluation system.
Recommendations covered topics related to the clinical management of chronic pancreatitis: aetiology, diagnosis of chronic pancreatitis with imaging, diagnosis of pancreatic exocrine insufficiency, surgical therapy, medical therapy, endoscopic therapy, treatment of pancreatic pseudocysts, pancreatic pain, nutrition and malnutrition, diabetes mellitus and the natural course of the disease and quality of life.
The HaPanEU/United European Gastroenterology guidelines provide evidence-based recommendations concerning key aspects of the medical and surgical management of chronic pancreatitis based on current available evidence. These recommendations should serve as a reference standard for existing management of the disease and as a guide for future clinical research. This article summarises the HaPanEU recommendations and statements.