The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle

Abstract One of the obstacles to the potential clinical utility of bioengineered skeletal muscle is its limited force generation capacity. Since engineered muscle, unlike most native muscle tissue, is composed of relatively short myofibers, we hypothesized that, its force production and transmission...

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Bibliographic Details
Published in:	Biomaterials Vol. 32; no. 14; pp. 3575 - 3583
Main Authors:	Hinds, Sara, Bian, Weining, Dennis, Robert G, Bursac, Nenad
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-05-2011
Subjects:	Advanced Basic Science Animals Bioengineering Bioengineering - methods Bundles Calcium - metabolism Cells, Cultured Collagens Contractile force Dentistry Extracellular Matrix - metabolism Fibrin Hydrogel Hydrogels - chemistry Muscle, Skeletal - pathology Muscles Myogenesis Obstacles Proteins Rats Rats, Sprague-Dawley Skeletal myoblasts Hydrogel Skeletal myoblasts Contractile force Myogenesis
Online Access:	Get full text
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