Undifferentiated Embryonal Sarcoma of the Liver Identified after the Initial Diagnosis of a Hepatic Cyst

• Published in: Internal Medicine Vol. 59; no. 19; pp. 2375 - 2382
• Main Authors: Manabe, Yusaku, Uojima, Haruki, Hidaka, Hisashi, Shao, Xue, Iwasaki, Shuichiro, Wada, Naohisa, Kubota, Kousuke, Tanaka, Yoshiaki, Nakazawa, Takahide, Shibuya, Akitaka, Ichinoe, Masaaki, Kumamoto, Yusuke, Kaizu, Takashi, Koizumi, Wasaburo
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01-10-2020; Japan Science and Technology Agency
• Subjects: Case Report; Computed tomography; cystic lesion; Cysts; Cysts - diagnosis; Cysts - surgery; Diagnosis; Fatal Outcome; Hepatectomy; Hepatectomy - methods; Humans; hydatid cyst; Immunohistochemistry; Internal medicine; Laparoscopy; Lesions; Liver; Liver Diseases - diagnosis; Liver Diseases - surgery; Liver Neoplasms - diagnosis; Liver Neoplasms - surgery; Male; Metastases; Middle Aged; Neoplasm Recurrence, Local - diagnosis; Neoplasm Recurrence, Local - surgery; Neoplasms, Germ Cell and Embryonal - diagnosis; Neoplasms, Germ Cell and Embryonal - surgery; Sarcoma; Sarcoma - diagnosis; Sarcoma - surgery; Tomography, X-Ray Computed - methods; Ultrasound; undifferentiated embryonal liver sarcoma; hydatid cyst; cystic lesion; undifferentiated embryonal liver sarcoma
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.4853-20

Abdominal ultrasound in a 50-year-old Japanese man revealed a cystic lesion on the caudate lobe of the liver. Four-month follow-up imaging showed a rapid increase in the size of the cystic lesion. The patient underwent laparoscopic partial hepatectomy because of a suspicion and perceived risk that the lesion might be malignant. The initial histological diagnosis was a hepatic cyst. Eleven months later, computed tomography showed a giant cystic lesion in the abdominal cavity and multiple liver metastases. The patient underwent excision of the giant cystic lesion and a partial hepatectomy. Immunohistochemistry for the recurring lesion revealed undifferentiated embryonal sarcoma of the liver.