LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein
LIS1 was first identified as a gene mutated in human classical lissencephaly sequence. LIS1 is required for dynein activity, but the underlying mechanism is poorly understood. Here, we demonstrate that LIS1 suppresses the motility of cytoplasmic dynein on microtubules (MTs), whereas NDEL1 releases t...
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| Published in: | The EMBO journal Vol. 27; no. 19; pp. 2471 - 2483 |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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Chichester, UK
John Wiley & Sons, Ltd
08-10-2008
Nature Publishing Group UK Blackwell Publishing Ltd Nature Publishing Group |
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| Abstract | LIS1 was first identified as a gene mutated in human classical lissencephaly sequence. LIS1 is required for dynein activity, but the underlying mechanism is poorly understood. Here, we demonstrate that LIS1 suppresses the motility of cytoplasmic dynein on microtubules (MTs), whereas NDEL1 releases the blocking effect of LIS1 on cytoplasmic dynein. We demonstrate that LIS1, cytoplasmic dynein and MT fragments co‐migrate anterogradely. When LIS1 function was suppressed by a blocking antibody, anterograde movement of cytoplasmic dynein was severely impaired. Immunoprecipitation assay indicated that cytoplasmic dynein forms a complex with LIS1, tubulins and kinesin‐1. In contrast, immunoabsorption of LIS1 resulted in disappearance of co‐precipitated tubulins and kinesin. Thus, we propose a novel model of the regulation of cytoplasmic dynein by LIS1, in which LIS1 mediates anterograde transport of cytoplasmic dynein to the plus end of cytoskeletal MTs as a dynein‐LIS1 complex on transportable MTs, which is a possibility supported by our data. |
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| AbstractList | LIS1 was first identified as a gene mutated in human classical lissencephaly sequence. LIS1 is required for dynein activity, but the underlying mechanism is poorly understood. Here, we demonstrate that LIS1 suppresses the motility of cytoplasmic dynein on microtubules (MTs), whereas NDEL1 releases the blocking effect of LIS1 on cytoplasmic dynein. We demonstrate that LIS1, cytoplasmic dynein and MT fragments co-migrate anterogradely. When LIS1 function was suppressed by a blocking antibody, anterograde movement of cytoplasmic dynein was severely impaired. Immunoprecipitation assay indicated that cytoplasmic dynein forms a complex with LIS1, tubulins and kinesin-1. In contrast, immunoabsorption of LIS1 resulted in disappearance of co-precipitated tubulins and kinesin. Thus, we propose a novel model of the regulation of cytoplasmic dynein by LIS1, in which LIS1 mediates anterograde transport of cytoplasmic dynein to the plus end of cytoskeletal MTs as a dynein–LIS1 complex on transportable MTs, which is a possibility supported by our data. LIS1 was first identified as a gene mutated in human classical lissencephaly sequence. LIS1 is required for dynein activity, but the underlying mechanism is poorly understood. Here, we demonstrate that LIS1 suppresses the motility of cytoplasmic dynein on microtubules (MTs), whereas NDEL1 releases the blocking effect of LIS1 on cytoplasmic dynein. We demonstrate that LIS1, cytoplasmic dynein and MT fragments co-migrate anterogradely. When LIS1 function was suppressed by a blocking antibody, anterograde movement of cytoplasmic dynein was severely impaired. Immunoprecipitation assay indicated that cytoplasmic dynein forms a complex with LIS1, tubulins and kinesin-1. In contrast, immunoabsorption of LIS1 resulted in disappearance of co-precipitated tubulins and kinesin. Thus, we propose a novel model of the regulation of cytoplasmic dynein by LIS1, in which LIS1 mediates anterograde transport of cytoplasmic dynein to the plus end of cytoskeletal MTs as a dynein-LIS1 complex on transportable MTs, which is a possibility supported by our data. [PUBLICATION ABSTRACT] |
| Author | Nakamura, Takeshi Mori, Daisuke Yoshida, Yuko Itoh, Kyoko Toba, Shiori Setou, Mitsutoshi Fushiki, Shinji Haratani, Koji Wynshaw-Boris, Anthony Toyoshima, Yoko Y Torisawa, Takayuki Mimori-Kiyosue, Yuko Yano, Yoshihisa Yamada, Masami Hirotsune, Shinji |
| Author_xml | – sequence: 1 givenname: Masami surname: Yamada fullname: Yamada, Masami organization: Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan – sequence: 2 givenname: Shiori surname: Toba fullname: Toba, Shiori organization: Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan – sequence: 3 givenname: Yuko surname: Yoshida fullname: Yoshida, Yuko organization: Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan – sequence: 4 givenname: Koji surname: Haratani fullname: Haratani, Koji organization: Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan – sequence: 5 givenname: Daisuke surname: Mori fullname: Mori, Daisuke organization: Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan – sequence: 6 givenname: Yoshihisa surname: Yano fullname: Yano, Yoshihisa organization: Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan – sequence: 7 givenname: Yuko surname: Mimori-Kiyosue fullname: Mimori-Kiyosue, Yuko organization: Research Group for Cytoskeleton & Cell Motility, KAN Research Institute Inc., Kobe, Japan – sequence: 8 givenname: Takeshi surname: Nakamura fullname: Nakamura, Takeshi organization: Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan – sequence: 9 givenname: Kyoko surname: Itoh fullname: Itoh, Kyoko organization: Department of Pathology and Applied Neurobiology, Kyoto Prefectural University of Medicine Graduate School of Medical Sciences, Kyoto, Japan – sequence: 10 givenname: Shinji surname: Fushiki fullname: Fushiki, Shinji organization: Department of Pathology and Applied Neurobiology, Kyoto Prefectural University of Medicine Graduate School of Medical Sciences, Kyoto, Japan – sequence: 11 givenname: Mitsutoshi surname: Setou fullname: Setou, Mitsutoshi organization: Department of Molecular Anatomy, Hamamatsu University School of Medicine, Shizuoka, Japan – sequence: 12 givenname: Anthony surname: Wynshaw-Boris fullname: Wynshaw-Boris, Anthony organization: Department of Pediatrics and Institute for Human Genetics, UCSF School of Medicine, San Francisco, CA, USA – sequence: 13 givenname: Takayuki surname: Torisawa fullname: Torisawa, Takayuki organization: Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan – sequence: 14 givenname: Yoko Y surname: Toyoshima fullname: Toyoshima, Yoko Y organization: Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan – sequence: 15 givenname: Shinji surname: Hirotsune fullname: Hirotsune, Shinji email: shinjih@med.osaka-cu.ac.jp organization: Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/18784752$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1073/pnas.78.2.1033 10.1083/jcb.91.3.661 10.1016/j.neuron.2004.09.030 10.1128/MCB.25.17.7812-7827.2005 10.1126/science.271.5255.1539 10.1016/0962-8924(91)90066-I 10.1016/S0896-6273(00)00145-8 10.1523/JNEUROSCI.5095-05.2006 10.1038/330672a0 10.1016/S0896-6273(00)00146-X 10.1038/ng1169 10.1016/S0092-8674(88)80038-2 10.1001/jama.270.23.2838 10.1016/S0960-9822(02)01078-3 10.1083/jcb.200309025 10.1093/oxfordjournals.jbchem.a135616 10.1016/S0092-8674(00)00094-5 10.1083/jcb.200209022 10.1038/nrg799 10.1016/j.cell.2008.01.026 10.1523/JNEUROSCI.08-07-02394.1988 10.1038/35041020 10.1006/dbio.2000.9848 10.1016/0076-6879(82)85041-6 10.1038/1221 10.1083/jcb.200310097 10.1073/pnas.81.19.6044 10.1016/S0006-3495(00)76743-9 10.1016/S0960-9822(98)70232-5 10.1038/35082594 10.1038/332561a0 10.1083/jcb.150.3.681 10.1002/cm.20018 10.1093/hmg/ddi339 10.1016/S0076-6879(98)98017-X 10.1523/JNEUROSCI.15-02-00981.1995 10.1016/S0896-6273(00)00147-1 |
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| References | Shu T, Ayala R, Nguyen MD, Xie Z, Gleeson JG, Tsai LH (2004) Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning. Neuron 44: 263-277 Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S (2005) Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol 25: 7812-7827 Vallee R (1991) Cytoplasmic dynein: advances in microtubule-based motility. Trends Cell Biol 1: 25-29 Bingham JB, King SJ, Schroer TA (1998) Purification of dynactin and dynein from brain tissue. Methods Enzymol 298: 171-184 Wang Z, Sheetz MP (2000) The C-terminus of tubulin increases cytoplasmic dynein and kinesin processivity. Biophys J 78: 1955-1964 Dujardin DL, Barnhart LE, Stehman SA, Gomes ER, Gundersen GG, Vallee RB (2003) A role for cytoplasmic dynein and LIS1 in directed cell movement. J Cell Biol 163: 1205-1211 Wang L, Brown A (2002) Rapid movement of microtubules in axons. Curr Biol 12: 1496-1501 Bouchard P, Penningroth SM, Cheung A, Gagnon C, Bardin CW (1981) erythro-9-[3-(2-Hydroxynonyl)]adenine is an inhibitor of sperm motility that blocks dynein ATPase and protein carboxylmethylase activities. Proc Natl Acad Sci USA 78: 1033-1036 Mesngon MT, Tarricone C, Hebbar S, Guillotte AM, Schmitt EW, Lanier L, Musacchio A, King SJ, Smith DS (2006) Regulation of cytoplasmic dynein ATPase by Lis1. J Neurosci 26: 2132-2139 Gupta A, Tsai LH, Wynshaw-Boris A (2002) Life is a journey: a genetic look at neocortical development. Nat Rev Genet 3: 342-355 Vale RD, Toyoshima YY (1988) Rotation and translocation of microtubules in vitro induced by dyneins from Tetrahymena cilia. Cell 52: 459-469 Vallee RB, Wall JS, Paschal BM, Shpetner HS (1988) Microtubule-associated protein 1C from brain is a two-headed cytosolic dynein. Nature 332: 561-563 Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY (1998) The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC. Curr Biol 8: 603-606 Yingling J, Youn YH, Darling D, Toyo-Oka K, Pramparo T, Hirotsune S, Wynshaw-Boris A (2008) Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell 132: 474-486 Lei Y, Warrior R (2000) The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration. Dev Biol 226: 57-72 Schliwa M, Ezzell RM, Euteneuer U (1984) erythro-9-[3-(2-Hydroxynonyl)]adenine is an effective inhibitor of cell motility and actin assembly. Proc Natl Acad Sci USA 81: 6044-6048 Heidemann SR, Landers JM, Hamborg MA (1981) Polarity orientation of axonal microtubules. J Cell Biol 91: 661-665 Hirotsune S, Fleck MW, Gambello MJ, Bix GJ, Chen A, Clark GD, Ledbetter DH, McBain CJ, Wynshaw-Boris A (1998) Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet 19: 333-339 Terada S, Kinjo M, Hirokawa N (2000) Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons. Cell 103: 141-155 Lindsay RM (1988) Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons. J Neurosci 8: 2394-2405 Dobyns WB, Curry CJ, Hoyme HE, Turlington L, Ledbetter DH (1991) Clinical and molecular diagnosis of Miller-Dieker syndrome. Am J Hum Genet 48: 584-594 Efimov VP, Morris NR (2000) The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein. J Cell Biol 150: 681-688 Faulkner NE, Dujardin DL, Tai CY, Vaughan KT, O'Connell CB, Wang Y, Vallee RB (2000) A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol 2: 784-791 Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH (2000) NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron 28: 697-711 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A (2003) 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet 34: 274-285 Lee WL, Oberle JR, Cooper JA (2003) The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast. J Cell Biol 160: 355-364 Sloboda RD, Rosenbaum JL (1982) Purification and assay of microtubule-associated proteins (MAPs). Methods Enzymol 85 (Part B): 409-416 Mochizuki N, Yamashita S, Kurokawa K, Ohba Y, Nagai T, Miyawaki A, Matsuda M (2001) Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature 411: 1065-1068 Tanaka T, Serneo FF, Higgins C, Gambello MJ, Wynshaw-Boris A, Gleeson JG (2004) Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J Cell Biol 165: 709-721 Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S (2005) Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet 14: 3113-3128 Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S (2000) A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron 28: 681-696 Paschal BM, King SM, Moss AG, Collins CA, Vallee RB, Witman GB (1987) Isolated flagellar outer arm dynein translocates brain microtubules in vitro. Nature 330: 672-674 Dobyns WB, Reiner O, Carrozzo R, Ledbetter DH (1993) Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13. JAMA 270: 2838-2842 Feng Y, Olson EC, Stukenberg PT, Flanagan LA, Kirschner MW, Walsh CA (2000) LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron 28: 665-679 Rivas RJ, Hatten ME (1995) Motility and cytoskeletal organization of migrating cerebellar granule neurons. J Neurosci 15: 981-989 Toba S, Toyoshima YY (2004) Dissociation of double-headed cytoplasmic dynein into single-headed species and its motile properties. Cell Motil Cytoskeleton 58: 281-289 Vallee RB, Sheetz MP (1996) Targeting of motor proteins. Science 271: 1539-1544 Kodama T, Fukui K, Kometani K (1986) The initial phosphate burst in ATP hydrolysis by myosin and subfragment-1 as studied by a modified malachite green method for determination of inorganic phosphate. J Biochem (Tokyo) 99: 1465-1472 Vallee, R (b33) 1991; 1 Wang, Z, Sheetz, MP (b37) 2000; 78 Efimov, VP, Morris, NR (b6) 2000; 150 Schliwa, M, Ezzell, RM, Euteneuer, U (b24) 1984; 81 Kodama, T, Fukui, K, Kometani, K (b12) 1986; 99 Dobyns, WB, Curry, CJ, Hoyme, HE, Turlington, L, Ledbetter, DH (b3) 1991; 48 Tanaka, T, Serneo, FF, Higgins, C, Gambello, MJ, Wynshaw-Boris, A, Gleeson, JG (b27) 2004; 165 Dobyns, WB, Reiner, O, Carrozzo, R, Ledbetter, DH (b4) 1993; 270 Vallee, RB, Sheetz, MP (b34) 1996; 271 Faulkner, NE, Dujardin, DL, Tai, CY, Vaughan, KT, O’Connell, CB, Wang, Y, Vallee, RB (b7) 2000; 2 Hirotsune, S, Fleck, MW, Gambello, MJ, Bix, GJ, Chen, A, Clark, GD, Ledbetter, DH, McBain, CJ, Wynshaw-Boris, A (b11) 1998; 19 Sasaki, S, Shionoya, A, Ishida, M, Gambello, MJ, Yingling, J, Wynshaw-Boris, A, Hirotsune, S (b23) 2000; 28 Gupta, A, Tsai, LH, Wynshaw-Boris, A (b9) 2002; 3 Sloboda, RD, Rosenbaum, JL (b26) 1982; 85 Niethammer, M, Smith, DS, Ayala, R, Peng, J, Ko, J, Lee, MS, Morabito, M, Tsai, LH (b19) 2000; 28 Vallee, RB, Wall, JS, Paschal, BM, Shpetner, HS (b35) 1988; 332 Lei, Y, Warrior, R (b14) 2000; 226 Paschal, BM, King, SM, Moss, AG, Collins, CA, Vallee, RB, Witman, GB (b20) 1987; 330 Yingling, J, Youn, YH, Darling, D, Toyo-Oka, K, Pramparo, T, Hirotsune, S, Wynshaw-Boris, A (b38) 2008; 132 Bouchard, P, Penningroth, SM, Cheung, A, Gagnon, C, Bardin, CW (b2) 1981; 78 Feng, Y, Olson, EC, Stukenberg, PT, Flanagan, LA, Kirschner, MW, Walsh, CA (b8) 2000; 28 Sasaki, S, Mori, D, Toyo-oka, K, Chen, A, Garrett-Beal, L, Muramatsu, M, Miyagawa, S, Hiraiwa, N, Yoshiki, A, Wynshaw-Boris, A, Hirotsune, S (b22) 2005; 25 Heidemann, SR, Landers, JM, Hamborg, MA (b10) 1981; 91 Mesngon, MT, Tarricone, C, Hebbar, S, Guillotte, AM, Schmitt, EW, Lanier, L, Musacchio, A, King, SJ, Smith, DS (b16) 2006; 26 Morris, SM, Albrecht, U, Reiner, O, Eichele, G, Yu-Lee, LY (b18) 1998; 8 Lindsay, RM (b15) 1988; 8 Mochizuki, N, Yamashita, S, Kurokawa, K, Ohba, Y, Nagai, T, Miyawaki, A, Matsuda, M (b17) 2001; 411 Toba, S, Toyoshima, YY (b29) 2004; 58 Wang, L, Brown, A (b36) 2002; 12 Bingham, JB, King, SJ, Schroer, TA (b1) 1998; 298 Rivas, RJ, Hatten, ME (b21) 1995; 15 Shu, T, Ayala, R, Nguyen, MD, Xie, Z, Gleeson, JG, Tsai, LH (b25) 2004; 44 Dujardin, DL, Barnhart, LE, Stehman, SA, Gomes, ER, Gundersen, GG, Vallee, RB (b5) 2003; 163 Terada, S, Kinjo, M, Hirokawa, N (b28) 2000; 103 Toyo-Oka, K, Sasaki, S, Yano, Y, Mori, D, Kobayashi, T, Toyoshima, YY, Tokuoka, SM, Ishii, S, Shimizu, T, Muramatsu, M, Hiraiwa, N, Yoshiki, A, Wynshaw-Boris, A, Hirotsune, S (b30) 2005; 14 Vale, RD, Toyoshima, YY (b32) 1988; 52 Lee, WL, Oberle, JR, Cooper, JA (b13) 2003; 160 Toyo-oka, K, Shionoya, A, Gambello, MJ, Cardoso, C, Leventer, R, Ward, HL, Ayala, R, Tsai, LH, Dobyns, W, Ledbetter, D, Hirotsune, S, Wynshaw-Boris, A (b31) 2003; 34 Lindsay (CR15) 1988; 8 Schliwa, Ezzell, Euteneuer (CR24) 1984; 81 Vallee (CR33) 1991; 1 Lee, Oberle, Cooper (CR13) 2003; 160 Niethammer, Smith, Ayala, Peng, Ko, Lee, Morabito, Tsai (CR19) 2000; 28 Heidemann, Landers, Hamborg (CR10) 1981; 91 Kodama, Fukui, Kometani (CR12) 1986; 99 Faulkner, Dujardin, Tai, Vaughan, O'Connell, Wang, Vallee (CR7) 2000; 2 Dobyns, Reiner, Carrozzo, Ledbetter (CR4) 1993; 270 Toba, Toyoshima (CR29) 2004; 58 Sasaki, Mori, Toyo‐oka, Chen, Garrett‐Beal, Muramatsu, Miyagawa, Hiraiwa, Yoshiki, Wynshaw‐Boris, Hirotsune (CR22) 2005; 25 Gupta, Tsai, Wynshaw‐Boris (CR9) 2002; 3 Terada, Kinjo, Hirokawa (CR28) 2000; 103 Tanaka, Serneo, Higgins, Gambello, Wynshaw‐Boris, Gleeson (CR27) 2004; 165 Morris, Albrecht, Reiner, Eichele, Yu‐Lee (CR18) 1998; 8 Vale, Toyoshima (CR32) 1988; 52 Mochizuki, Yamashita, Kurokawa, Ohba, Nagai, Miyawaki, Matsuda (CR17) 2001; 411 Paschal, King, Moss, Collins, Vallee, Witman (CR20) 1987; 330 Vallee, Wall, Paschal, Shpetner (CR35) 1988; 332 Wang, Sheetz (CR37) 2000; 78 Bingham, King, Schroer (CR1) 1998; 298 Dobyns, Curry, Hoyme, Turlington, Ledbetter (CR3) 1991; 48 Efimov, Morris (CR6) 2000; 150 Yingling, Youn, Darling, Toyo‐Oka, Pramparo, Hirotsune, Wynshaw‐Boris (CR38) 2008; 132 Bouchard, Penningroth, Cheung, Gagnon, Bardin (CR2) 1981; 78 Hirotsune, Fleck, Gambello, Bix, Chen, Clark, Ledbetter, McBain, Wynshaw‐Boris (CR11) 1998; 19 Sasaki, Shionoya, Ishida, Gambello, Yingling, Wynshaw‐Boris, Hirotsune (CR23) 2000; 28 Mesngon, Tarricone, Hebbar, Guillotte, Schmitt, Lanier, Musacchio, King, Smith (CR16) 2006; 26 Dujardin, Barnhart, Stehman, Gomes, Gundersen, Vallee (CR5) 2003; 163 Sloboda, Rosenbaum (CR26) 1982; 85 Wang, Brown (CR36) 2002; 12 Rivas, Hatten (CR21) 1995; 15 Shu, Ayala, Nguyen, Xie, Gleeson, Tsai (CR25) 2004; 44 Lei, Warrior (CR14) 2000; 226 Toyo‐Oka, Sasaki, Yano, Mori, Kobayashi, Toyoshima, Tokuoka, Ishii, Shimizu, Muramatsu, Hiraiwa, Yoshiki, Wynshaw‐Boris, Hirotsune (CR30) 2005; 14 Vallee, Sheetz (CR34) 1996; 271 Feng, Olson, Stukenberg, Flanagan, Kirschner, Walsh (CR8) 2000; 28 Toyo‐oka, Shionoya, Gambello, Cardoso, Leventer, Ward, Ayala, Tsai, Dobyns, Ledbetter, Hirotsune, Wynshaw‐Boris (CR31) 2003; 34 2004; 44 2004; 165 1991; 1 1984; 81 2000; 28 1981; 91 1995; 15 1986; 99 2002; 12 2000; 150 2002; 3 2000; 2 1988; 52 1998; 298 2005; 25 2003; 34 1998; 19 1987; 330 1991; 48 2000; 103 2000; 78 2000; 226 1982; 85 2004; 58 1988; 8 2006; 26 1993; 270 1996; 271 2003; 160 1988; 332 2008; 132 2001; 411 1981; 78 2003; 163 1998; 8 2005; 14 16481446 - J Neurosci. 2006 Feb 15;26(7):2132-9 10993674 - Dev Biol. 2000 Oct 1;226(1):57-72 16107726 - Mol Cell Biol. 2005 Sep;25(17):7812-27 11056532 - Nat Cell Biol. 2000 Nov;2(11):784-91 6173385 - J Cell Biol. 1981 Dec;91(3 Pt 1):661-5 11051554 - Cell. 2000 Sep 29;103(1):141-55 2964278 - Cell. 1988 Feb 12;52(3):459-69 1671808 - Am J Hum Genet. 1991 Mar;48(3):584-94 12566428 - J Cell Biol. 2003 Feb 3;160(3):355-64 6453342 - Proc Natl Acad Sci U S A. 1981 Feb;78(2):1033-6 15236358 - Cell Motil Cytoskeleton. 2004 Aug;58(4):281-9 11988760 - Nat Rev Genet. 2002 May;3(5):342-55 12796778 - Nat Genet. 2003 Jul;34(3):274-85 11163258 - Neuron. 2000 Dec;28(3):665-79 7907669 - JAMA. 1993 Dec 15;270(23):2838-42 8599110 - Science. 1996 Mar 15;271(5255):1539-44 9697693 - Nat Genet. 1998 Aug;19(4):333-9 3249232 - J Neurosci. 1988 Jul;8(7):2394-405 15473966 - Neuron. 2004 Oct 14;44(2):263-77 2940237 - J Biochem. 1986 May;99(5):1465-72 16203747 - Hum Mol Genet. 2005 Nov 1;14(21):3113-28 9601647 - Curr Biol. 1998 May 7;8(10):603-6 18267077 - Cell. 2008 Feb 8;132(3):474-86 9751880 - Methods Enzymol. 1998;298:171-84 10931877 - J Cell Biol. 2000 Aug 7;150(3):681-8 10733974 - Biophys J. 2000 Apr;78(4):1955-64 11429608 - Nature. 2001 Jun 28;411(6841):1065-8 7121279 - Methods Enzymol. 1982;85 Pt B:409-16 15173193 - J Cell Biol. 2004 Jun 7;165(5):709-21 7869123 - J Neurosci. 1995 Feb;15(2):981-9 14731806 - Trends Cell Biol. 1991 Jul;1(1):25-9 2960903 - Nature. 1987 Dec 17-23;330(6149):672-4 11163259 - Neuron. 2000 Dec;28(3):681-96 11163260 - Neuron. 2000 Dec;28(3):697-711 6385006 - Proc Natl Acad Sci U S A. 1984 Oct;81(19):6044-8 14691133 - J Cell Biol. 2003 Dec 22;163(6):1205-11 12225664 - Curr Biol. 2002 Sep 3;12(17):1496-1501 2965791 - Nature. 1988 Apr 7;332(6164):561-3 emboj2008182-b18 emboj2008182-b19 emboj2008182-b14 emboj2008182-b36 emboj2008182-b16 emboj2008182-b38 emboj2008182-b17 emboj2008182-b10 emboj2008182-b32 emboj2008182-b11 emboj2008182-b33 Kodama T (emboj2008182-b12) 1986; 99 emboj2008182-b34 emboj2008182-b13 emboj2008182-b35 Wang Z (emboj2008182-b37) 2000; 78 emboj2008182-b30 emboj2008182-b31 emboj2008182-b2 emboj2008182-b1 emboj2008182-b4 Rivas RJ (emboj2008182-b21) 1995; 15 emboj2008182-b29 emboj2008182-b25 emboj2008182-b27 Sloboda RD (emboj2008182-b26) 1982; 85 emboj2008182-b28 emboj2008182-b9 emboj2008182-b22 Dobyns WB (emboj2008182-b3) 1991; 48 emboj2008182-b23 emboj2008182-b24 emboj2008182-b6 emboj2008182-b5 emboj2008182-b8 emboj2008182-b7 Lindsay RM (emboj2008182-b15) 1988; 8 emboj2008182-b20 |
| References_xml | – volume: 58 start-page: 281 year: 2004 end-page: 289 ident: b29 publication-title: Cell Motil Cytoskeleton contributor: fullname: Toyoshima, YY – volume: 91 start-page: 661 year: 1981 end-page: 665 ident: b10 publication-title: J Cell Biol contributor: fullname: Hamborg, MA – volume: 12 start-page: 1496 year: 2002 end-page: 1501 ident: b36 publication-title: Curr Biol contributor: fullname: Brown, A – volume: 8 start-page: 2394 year: 1988 end-page: 2405 ident: b15 publication-title: J Neurosci contributor: fullname: Lindsay, RM – volume: 28 start-page: 681 year: 2000 end-page: 696 ident: b23 publication-title: Neuron contributor: fullname: Hirotsune, S – volume: 1 start-page: 25 year: 1991 end-page: 29 ident: b33 publication-title: Trends Cell Biol contributor: fullname: Vallee, R – volume: 271 start-page: 1539 year: 1996 end-page: 1544 ident: b34 publication-title: Science contributor: fullname: Sheetz, MP – volume: 78 start-page: 1955 year: 2000 end-page: 1964 ident: b37 publication-title: Biophys J contributor: fullname: Sheetz, MP – volume: 8 start-page: 603 year: 1998 end-page: 606 ident: b18 publication-title: Curr Biol contributor: fullname: Yu-Lee, LY – volume: 2 start-page: 784 year: 2000 end-page: 791 ident: b7 publication-title: Nat Cell Biol contributor: fullname: Vallee, RB – volume: 34 start-page: 274 year: 2003 end-page: 285 ident: b31 publication-title: Nat Genet contributor: fullname: Wynshaw-Boris, A – volume: 160 start-page: 355 year: 2003 end-page: 364 ident: b13 publication-title: J Cell Biol contributor: fullname: Cooper, JA – volume: 226 start-page: 57 year: 2000 end-page: 72 ident: b14 publication-title: Dev Biol contributor: fullname: Warrior, R – volume: 26 start-page: 2132 year: 2006 end-page: 2139 ident: b16 publication-title: J Neurosci contributor: fullname: Smith, DS – volume: 52 start-page: 459 year: 1988 end-page: 469 ident: b32 publication-title: Cell contributor: fullname: Toyoshima, YY – volume: 298 start-page: 171 year: 1998 end-page: 184 ident: b1 publication-title: Methods Enzymol contributor: fullname: Schroer, TA – volume: 19 start-page: 333 year: 1998 end-page: 339 ident: b11 publication-title: Nat Genet contributor: fullname: Wynshaw-Boris, A – volume: 165 start-page: 709 year: 2004 end-page: 721 ident: b27 publication-title: J Cell Biol contributor: fullname: Gleeson, JG – volume: 163 start-page: 1205 year: 2003 end-page: 1211 ident: b5 publication-title: J Cell Biol contributor: fullname: Vallee, RB – volume: 330 start-page: 672 year: 1987 end-page: 674 ident: b20 publication-title: Nature contributor: fullname: Witman, GB – volume: 28 start-page: 697 year: 2000 end-page: 711 ident: b19 publication-title: Neuron contributor: fullname: Tsai, LH – volume: 15 start-page: 981 year: 1995 end-page: 989 ident: b21 publication-title: J Neurosci contributor: fullname: Hatten, ME – volume: 81 start-page: 6044 year: 1984 end-page: 6048 ident: b24 publication-title: Proc Natl Acad Sci USA contributor: fullname: Euteneuer, U – volume: 270 start-page: 2838 year: 1993 end-page: 2842 ident: b4 publication-title: JAMA contributor: fullname: Ledbetter, DH – volume: 44 start-page: 263 year: 2004 end-page: 277 ident: b25 publication-title: Neuron contributor: fullname: Tsai, LH – volume: 78 start-page: 1033 year: 1981 end-page: 1036 ident: b2 publication-title: Proc Natl Acad Sci USA contributor: fullname: Bardin, CW – volume: 28 start-page: 665 year: 2000 end-page: 679 ident: b8 publication-title: Neuron contributor: fullname: Walsh, CA – volume: 99 start-page: 1465 year: 1986 end-page: 1472 ident: b12 publication-title: J Biochem (Tokyo) contributor: fullname: Kometani, K – volume: 85 start-page: 409 issue: (Part B) year: 1982 end-page: 416 ident: b26 publication-title: Methods Enzymol contributor: fullname: Rosenbaum, JL – volume: 14 start-page: 3113 year: 2005 end-page: 3128 ident: b30 publication-title: Hum Mol Genet contributor: fullname: Hirotsune, S – volume: 3 start-page: 342 year: 2002 end-page: 355 ident: b9 publication-title: Nat Rev Genet contributor: fullname: Wynshaw-Boris, A – volume: 132 start-page: 474 year: 2008 end-page: 486 ident: b38 publication-title: Cell contributor: fullname: Wynshaw-Boris, A – volume: 48 start-page: 584 year: 1991 end-page: 594 ident: b3 publication-title: Am J Hum Genet contributor: fullname: Ledbetter, DH – volume: 150 start-page: 681 year: 2000 end-page: 688 ident: b6 publication-title: J Cell Biol contributor: fullname: Morris, NR – volume: 411 start-page: 1065 year: 2001 end-page: 1068 ident: b17 publication-title: Nature contributor: fullname: Matsuda, M – volume: 25 start-page: 7812 year: 2005 end-page: 7827 ident: b22 publication-title: Mol Cell Biol contributor: fullname: Hirotsune, S – volume: 103 start-page: 141 year: 2000 end-page: 155 ident: b28 publication-title: Cell contributor: fullname: Hirokawa, N – volume: 332 start-page: 561 year: 1988 end-page: 563 ident: b35 publication-title: Nature contributor: fullname: Shpetner, HS – volume: 85 start-page: 409 year: 1982 end-page: 416 ident: CR26 article-title: Purification and assay of microtubule‐associated proteins (MAPs) publication-title: Methods Enzymol contributor: fullname: Rosenbaum – volume: 163 start-page: 1205 year: 2003 end-page: 1211 ident: CR5 article-title: A role for cytoplasmic dynein and LIS1 in directed cell movement publication-title: J Cell Biol contributor: fullname: Vallee – volume: 330 start-page: 672 year: 1987 end-page: 674 ident: CR20 article-title: Isolated flagellar outer arm dynein translocates brain microtubules publication-title: Nature contributor: fullname: Witman – volume: 15 start-page: 981 year: 1995 end-page: 989 ident: CR21 article-title: Motility and cytoskeletal organization of migrating cerebellar granule neurons publication-title: J Neurosci contributor: fullname: Hatten – volume: 25 start-page: 7812 year: 2005 end-page: 7827 ident: CR22 article-title: Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality publication-title: Mol Cell Biol contributor: fullname: Hirotsune – volume: 91 start-page: 661 year: 1981 end-page: 665 ident: CR10 article-title: Polarity orientation of axonal microtubules publication-title: J Cell Biol contributor: fullname: Hamborg – volume: 2 start-page: 784 year: 2000 end-page: 791 ident: CR7 article-title: A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function publication-title: Nat Cell Biol contributor: fullname: Vallee – volume: 160 start-page: 355 year: 2003 end-page: 364 ident: CR13 article-title: The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast publication-title: J Cell Biol contributor: fullname: Cooper – volume: 1 start-page: 25 year: 1991 end-page: 29 ident: CR33 article-title: Cytoplasmic dynein: advances in microtubule‐based motility publication-title: Trends Cell Biol contributor: fullname: Vallee – volume: 99 start-page: 1465 year: 1986 end-page: 1472 ident: CR12 article-title: The initial phosphate burst in ATP hydrolysis by myosin and subfragment‐1 as studied by a modified malachite green method for determination of inorganic phosphate publication-title: J Biochem (Tokyo) contributor: fullname: Kometani – volume: 14 start-page: 3113 year: 2005 end-page: 3128 ident: CR30 article-title: Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration publication-title: Hum Mol Genet contributor: fullname: Hirotsune – volume: 8 start-page: 603 year: 1998 end-page: 606 ident: CR18 article-title: The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC publication-title: Curr Biol contributor: fullname: Yu‐Lee – volume: 165 start-page: 709 year: 2004 end-page: 721 ident: CR27 article-title: Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration publication-title: J Cell Biol contributor: fullname: Gleeson – volume: 78 start-page: 1955 year: 2000 end-page: 1964 ident: CR37 article-title: The C‐terminus of tubulin increases cytoplasmic dynein and kinesin processivity publication-title: Biophys J contributor: fullname: Sheetz – volume: 28 start-page: 697 year: 2000 end-page: 711 ident: CR19 article-title: NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein publication-title: Neuron contributor: fullname: Tsai – volume: 48 start-page: 584 year: 1991 end-page: 594 ident: CR3 article-title: Clinical and molecular diagnosis of Miller‐Dieker syndrome publication-title: Am J Hum Genet contributor: fullname: Ledbetter – volume: 3 start-page: 342 year: 2002 end-page: 355 ident: CR9 article-title: Life is a journey: a genetic look at neocortical development publication-title: Nat Rev Genet contributor: fullname: Wynshaw‐Boris – volume: 44 start-page: 263 year: 2004 end-page: 277 ident: CR25 article-title: Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning publication-title: Neuron contributor: fullname: Tsai – volume: 12 start-page: 1496 year: 2002 end-page: 1501 ident: CR36 article-title: Rapid movement of microtubules in axons publication-title: Curr Biol contributor: fullname: Brown – volume: 28 start-page: 681 year: 2000 end-page: 696 ident: CR23 article-title: A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system publication-title: Neuron contributor: fullname: Hirotsune – volume: 332 start-page: 561 year: 1988 end-page: 563 ident: CR35 article-title: Microtubule‐associated protein 1C from brain is a two‐headed cytosolic dynein publication-title: Nature contributor: fullname: Shpetner – volume: 28 start-page: 665 year: 2000 end-page: 679 ident: CR8 article-title: LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome publication-title: Neuron contributor: fullname: Walsh – volume: 34 start-page: 274 year: 2003 end-page: 285 ident: CR31 article-title: 14‐3‐3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller‐Dieker syndrome publication-title: Nat Genet contributor: fullname: Wynshaw‐Boris – volume: 226 start-page: 57 year: 2000 end-page: 72 ident: CR14 article-title: The Lissencephaly1 (DLis1) gene is required for nuclear migration publication-title: Dev Biol contributor: fullname: Warrior – volume: 81 start-page: 6044 year: 1984 end-page: 6048 ident: CR24 article-title: erythro‐9‐[3‐(2‐Hydroxynonyl)]adenine is an effective inhibitor of cell motility and actin assembly publication-title: Proc Natl Acad Sci USA contributor: fullname: Euteneuer – volume: 132 start-page: 474 year: 2008 end-page: 486 ident: CR38 article-title: Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division publication-title: Cell contributor: fullname: Wynshaw‐Boris – volume: 8 start-page: 2394 year: 1988 end-page: 2405 ident: CR15 article-title: Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons publication-title: J Neurosci contributor: fullname: Lindsay – volume: 270 start-page: 2838 year: 1993 end-page: 2842 ident: CR4 article-title: Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13 publication-title: JAMA contributor: fullname: Ledbetter – volume: 150 start-page: 681 year: 2000 end-page: 688 ident: CR6 article-title: The LIS1‐related NUDF protein of interacts with the coiled‐coil domain of the NUDE/RO11 protein publication-title: J Cell Biol contributor: fullname: Morris – volume: 52 start-page: 459 year: 1988 end-page: 469 ident: CR32 article-title: Rotation and translocation of microtubules induced by dyneins from publication-title: Cell contributor: fullname: Toyoshima – volume: 78 start-page: 1033 year: 1981 end-page: 1036 ident: CR2 article-title: erythro‐9‐[3‐(2‐Hydroxynonyl)]adenine is an inhibitor of sperm motility that blocks dynein ATPase and protein carboxylmethylase activities publication-title: Proc Natl Acad Sci USA contributor: fullname: Bardin – volume: 411 start-page: 1065 year: 2001 end-page: 1068 ident: CR17 article-title: Spatio‐temporal images of growth‐factor‐induced activation of Ras and Rap1 publication-title: Nature contributor: fullname: Matsuda – volume: 103 start-page: 141 year: 2000 end-page: 155 ident: CR28 article-title: Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons publication-title: Cell contributor: fullname: Hirokawa – volume: 58 start-page: 281 year: 2004 end-page: 289 ident: CR29 article-title: Dissociation of double‐headed cytoplasmic dynein into single‐headed species and its motile properties publication-title: Cell Motil Cytoskeleton contributor: fullname: Toyoshima – volume: 26 start-page: 2132 year: 2006 end-page: 2139 ident: CR16 article-title: Regulation of cytoplasmic dynein ATPase by Lis1 publication-title: J Neurosci contributor: fullname: Smith – volume: 271 start-page: 1539 year: 1996 end-page: 1544 ident: CR34 article-title: Targeting of motor proteins publication-title: Science contributor: fullname: Sheetz – volume: 298 start-page: 171 year: 1998 end-page: 184 ident: CR1 article-title: Purification of dynactin and dynein from brain tissue publication-title: Methods Enzymol contributor: fullname: Schroer – volume: 19 start-page: 333 year: 1998 end-page: 339 ident: CR11 article-title: Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality publication-title: Nat Genet contributor: fullname: Wynshaw‐Boris – volume: 85 start-page: 409 year: 1982 end-page: 416 article-title: Purification and assay of microtubule‐associated proteins (MAPs) publication-title: Methods Enzymol – volume: 150 start-page: 681 year: 2000 end-page: 688 article-title: The LIS1‐related NUDF protein of interacts with the coiled‐coil domain of the NUDE/RO11 protein publication-title: J Cell Biol – volume: 15 start-page: 981 year: 1995 end-page: 989 article-title: Motility and cytoskeletal organization of migrating cerebellar granule neurons publication-title: J Neurosci – volume: 34 start-page: 274 year: 2003 end-page: 285 article-title: 14‐3‐3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller‐Dieker syndrome publication-title: Nat Genet – volume: 270 start-page: 2838 year: 1993 end-page: 2842 article-title: Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13 publication-title: JAMA – volume: 298 start-page: 171 year: 1998 end-page: 184 article-title: Purification of dynactin and dynein from brain tissue publication-title: Methods Enzymol – volume: 103 start-page: 141 year: 2000 end-page: 155 article-title: Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons publication-title: Cell – volume: 8 start-page: 2394 year: 1988 end-page: 2405 article-title: Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons publication-title: J Neurosci – volume: 332 start-page: 561 year: 1988 end-page: 563 article-title: Microtubule‐associated protein 1C from brain is a two‐headed cytosolic dynein publication-title: Nature – volume: 3 start-page: 342 year: 2002 end-page: 355 article-title: Life is a journey: a genetic look at neocortical development publication-title: Nat Rev Genet – volume: 52 start-page: 459 year: 1988 end-page: 469 article-title: Rotation and translocation of microtubules induced by dyneins from publication-title: Cell – volume: 91 start-page: 661 year: 1981 end-page: 665 article-title: Polarity orientation of axonal microtubules publication-title: J Cell Biol – volume: 2 start-page: 784 year: 2000 end-page: 791 article-title: A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function publication-title: Nat Cell Biol – volume: 78 start-page: 1033 year: 1981 end-page: 1036 article-title: erythro‐9‐[3‐(2‐Hydroxynonyl)]adenine is an inhibitor of sperm motility that blocks dynein ATPase and protein carboxylmethylase activities publication-title: Proc Natl Acad Sci USA – volume: 78 start-page: 1955 year: 2000 end-page: 1964 article-title: The C‐terminus of tubulin increases cytoplasmic dynein and kinesin processivity publication-title: Biophys J – volume: 99 start-page: 1465 year: 1986 end-page: 1472 article-title: The initial phosphate burst in ATP hydrolysis by myosin and subfragment‐1 as studied by a modified malachite green method for determination of inorganic phosphate publication-title: J Biochem (Tokyo) – volume: 165 start-page: 709 year: 2004 end-page: 721 article-title: Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration publication-title: J Cell Biol – volume: 163 start-page: 1205 year: 2003 end-page: 1211 article-title: A role for cytoplasmic dynein and LIS1 in directed cell movement publication-title: J Cell Biol – volume: 44 start-page: 263 year: 2004 end-page: 277 article-title: Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning publication-title: Neuron – volume: 19 start-page: 333 year: 1998 end-page: 339 article-title: Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality publication-title: Nat Genet – volume: 330 start-page: 672 year: 1987 end-page: 674 article-title: Isolated flagellar outer arm dynein translocates brain microtubules publication-title: Nature – volume: 14 start-page: 3113 year: 2005 end-page: 3128 article-title: Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration publication-title: Hum Mol Genet – volume: 81 start-page: 6044 year: 1984 end-page: 6048 article-title: erythro‐9‐[3‐(2‐Hydroxynonyl)]adenine is an effective inhibitor of cell motility and actin assembly publication-title: Proc Natl Acad Sci USA – volume: 132 start-page: 474 year: 2008 end-page: 486 article-title: Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division publication-title: Cell – volume: 271 start-page: 1539 year: 1996 end-page: 1544 article-title: Targeting of motor proteins publication-title: Science – volume: 1 start-page: 25 year: 1991 end-page: 29 article-title: Cytoplasmic dynein: advances in microtubule‐based motility publication-title: Trends Cell Biol – volume: 28 start-page: 681 year: 2000 end-page: 696 article-title: A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system publication-title: Neuron – volume: 28 start-page: 665 year: 2000 end-page: 679 article-title: LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome publication-title: Neuron – volume: 48 start-page: 584 year: 1991 end-page: 594 article-title: Clinical and molecular diagnosis of Miller‐Dieker syndrome publication-title: Am J Hum Genet – volume: 8 start-page: 603 year: 1998 end-page: 606 article-title: The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC publication-title: Curr Biol – volume: 26 start-page: 2132 year: 2006 end-page: 2139 article-title: Regulation of cytoplasmic dynein ATPase by Lis1 publication-title: J Neurosci – volume: 58 start-page: 281 year: 2004 end-page: 289 article-title: Dissociation of double‐headed cytoplasmic dynein into single‐headed species and its motile properties publication-title: Cell Motil Cytoskeleton – volume: 226 start-page: 57 year: 2000 end-page: 72 article-title: The Lissencephaly1 (DLis1) gene is required for nuclear migration publication-title: Dev Biol – volume: 411 start-page: 1065 year: 2001 end-page: 1068 article-title: Spatio‐temporal images of growth‐factor‐induced activation of Ras and Rap1 publication-title: Nature – volume: 28 start-page: 697 year: 2000 end-page: 711 article-title: NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein publication-title: Neuron – volume: 12 start-page: 1496 year: 2002 end-page: 1501 article-title: Rapid movement of microtubules in axons publication-title: Curr Biol – volume: 160 start-page: 355 year: 2003 end-page: 364 article-title: The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast publication-title: J Cell Biol – volume: 25 start-page: 7812 year: 2005 end-page: 7827 article-title: Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality publication-title: Mol Cell Biol – ident: emboj2008182-b2 doi: 10.1073/pnas.78.2.1033 – ident: emboj2008182-b10 doi: 10.1083/jcb.91.3.661 – ident: emboj2008182-b25 doi: 10.1016/j.neuron.2004.09.030 – ident: emboj2008182-b22 doi: 10.1128/MCB.25.17.7812-7827.2005 – ident: emboj2008182-b34 doi: 10.1126/science.271.5255.1539 – ident: emboj2008182-b33 doi: 10.1016/0962-8924(91)90066-I – ident: emboj2008182-b8 doi: 10.1016/S0896-6273(00)00145-8 – ident: emboj2008182-b16 doi: 10.1523/JNEUROSCI.5095-05.2006 – ident: emboj2008182-b20 doi: 10.1038/330672a0 – ident: emboj2008182-b23 doi: 10.1016/S0896-6273(00)00146-X – ident: emboj2008182-b31 doi: 10.1038/ng1169 – ident: emboj2008182-b32 doi: 10.1016/S0092-8674(88)80038-2 – ident: emboj2008182-b4 doi: 10.1001/jama.270.23.2838 – ident: emboj2008182-b36 doi: 10.1016/S0960-9822(02)01078-3 – ident: emboj2008182-b27 doi: 10.1083/jcb.200309025 – volume: 99 start-page: 1465 year: 1986 ident: emboj2008182-b12 publication-title: J Biochem (Tokyo) doi: 10.1093/oxfordjournals.jbchem.a135616 contributor: fullname: Kodama T – ident: emboj2008182-b28 doi: 10.1016/S0092-8674(00)00094-5 – ident: emboj2008182-b13 doi: 10.1083/jcb.200209022 – ident: emboj2008182-b9 doi: 10.1038/nrg799 – ident: emboj2008182-b38 doi: 10.1016/j.cell.2008.01.026 – volume: 8 start-page: 2394 year: 1988 ident: emboj2008182-b15 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.08-07-02394.1988 contributor: fullname: Lindsay RM – ident: emboj2008182-b7 doi: 10.1038/35041020 – ident: emboj2008182-b14 doi: 10.1006/dbio.2000.9848 – volume: 85 start-page: 409 year: 1982 ident: emboj2008182-b26 publication-title: Methods Enzymol doi: 10.1016/0076-6879(82)85041-6 contributor: fullname: Sloboda RD – ident: emboj2008182-b11 doi: 10.1038/1221 – ident: emboj2008182-b5 doi: 10.1083/jcb.200310097 – ident: emboj2008182-b24 doi: 10.1073/pnas.81.19.6044 – volume: 78 start-page: 1955 year: 2000 ident: emboj2008182-b37 publication-title: Biophys J doi: 10.1016/S0006-3495(00)76743-9 contributor: fullname: Wang Z – ident: emboj2008182-b18 doi: 10.1016/S0960-9822(98)70232-5 – ident: emboj2008182-b17 doi: 10.1038/35082594 – ident: emboj2008182-b35 doi: 10.1038/332561a0 – volume: 48 start-page: 584 year: 1991 ident: emboj2008182-b3 publication-title: Am J Hum Genet contributor: fullname: Dobyns WB – ident: emboj2008182-b6 doi: 10.1083/jcb.150.3.681 – ident: emboj2008182-b29 doi: 10.1002/cm.20018 – ident: emboj2008182-b30 doi: 10.1093/hmg/ddi339 – ident: emboj2008182-b1 doi: 10.1016/S0076-6879(98)98017-X – volume: 15 start-page: 981 year: 1995 ident: emboj2008182-b21 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.15-02-00981.1995 contributor: fullname: Rivas RJ – ident: emboj2008182-b19 doi: 10.1016/S0896-6273(00)00147-1 |
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| Title | LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein |
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