Effect of acute lateral hemisection of the spinal cord on spinal neurons of postural networks

• Published in: Neuroscience Vol. 339; pp. 235 - 253
• Main Authors: Zelenin, P.V, Lyalka, V.F, Orlovsky, G.N, Deliagina, T.G
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 17-12-2016
• Subjects: Animals; cat; Cold Temperature; Decerebrate State; Functional Laterality - physiology; Gray Matter - physiopathology; Medicin och hälsovetenskap; Microelectrodes; Muscle, Skeletal - physiopathology; Neural Pathways - physiopathology; Neurology; Neurons - physiology; Postural Balance - physiology; postural reflexes; Rabbits; Reflex - physiology; Spinal Cord - physiopathology; Spinal Cord Injuries - physiopathology; spinal cord injury; spinal networks; spinal neurons; spinal cord injury; Rev-LHS; postural limb reflexes; postural reflexes; Co; electromyogram; reversible lateral hemisection of the spinal cord; Sur-LHS; contralateral; lateral hemisection of the spinal cord; LHS; spinal neurons; cat; PLRs; ipsilateral; EMG; spinal networks; Ipsi; surgical lateral hemisection of the spinal cord
• ISSN: 0306-4522; 1873-7544; 1873-7544
• DOI: 10.1016/j.neuroscience.2016.09.043

Highlights • Acute lateral hemisection (LHS) of the spinal cord causes right-left asymmetry in postural limb reflexes. • We examine the effects of acute LHS on two populations of spinal interneurons (F and E) mediating postural limb reflexes. • LHS causes a reduction in the proportion of F-neurons on the lesioned side. • LHS causes a reduction in activity of E- and F-neurons located in specific areas of the gray matter. • These activity changes are due to specific changes in the efficacy of posture-related sensory inputs to F- and E-neurons.