Genetically resistant sheep avoid parasites to a greater extent than do susceptible sheep

• Published in: Proceedings of the Royal Society. B, Biological sciences Vol. 274; no. 1620; pp. 1839 - 1844
• Main Authors: Hutchings, M.R, Knowler, K.J, McAnulty, R, McEwan, J.C
• Format: Journal Article
• Language: English
• Published: London The Royal Society 07-08-2007
• Subjects: Animals; Behavior, Animal; Eggs; Forage; Genetic Predisposition to Disease; Grazing behavior; Grazing Behaviour; Herbivores; Larvae; Nitrogen; Parasite Avoidance; Parasite Resistance; Parasites; Parasitic Diseases, Animal - genetics; Parasitic Diseases, Animal - parasitology; Parasitism; Sheep; Sheep Diseases - genetics; Sheep Diseases - parasitology; Sward; Time Factors
• ISSN: 0962-8452; 1471-2954
• DOI: 10.1098/rspb.2007.0398

Livestock breeding programmes have created resistant (R) and susceptible (S) sheep that differ in their ability to control parasites through their immune function but potentially also their grazing behaviour (i.e. parasite avoidance). Using the Perendale genetic lines, we tested the hypothesis that R-sheep avoid parasites more effectively, reducing their parasite exposure/challenge, compared with S-sheep. However, in grazing systems, parasite-rich areas are also forage rich, suggesting that parasite avoidance behaviours are associated with nutritional penalties. We first created a naturally heterogeneous sward structure of gaps and tussocks and then used focal behavioural observations to quantify the sward selection of R- and S-sheep. Tussock swards were more nitrogen rich (41%), offered increased forage intake rates (32%) and contained 17 times more parasite larvae than gap swards. All the animals avoided grazing the tussock swards. However, the R-sheep grazed the tussock swards to a lesser degree than the S-sheep. We conclude that selection for genetic resistance has resulted in animals that, despite being well armed to fight parasitism through improved immune function, adopt parasite avoidance strategies with associated nutritional disadvantages. This experiment highlights the role of host behaviour in the control of parasitism and suggests that animals can be bred to avoid disease.