Biological links between traumatic brain injury and Parkinson's disease

Parkinson's Disease (PD) is a progressive neurodegenerative disorder with no cure. Clinical presentation is characterized by postural instability, resting tremors, and gait problems that result from progressive loss of A9 dopaminergic neurons in the substantia nigra pars compacta. Traumatic bra...

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Bibliographic Details
Published in:	Acta neuropathologica communications Vol. 8; no. 1; p. 45
Main Authors:	Delic, Vedad, Beck, Kevin D, Pang, Kevin C H, Citron, Bruce A
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 07-04-2020 BioMed Central BMC
Subjects:	alpha-Synuclein - metabolism Amyloid beta-protein Amyloid beta-Protein Precursor - metabolism Analysis Animals B cells Blood-Brain Barrier - metabolism Brain Brain damage Brain injuries Brain Injuries, Traumatic - epidemiology Brain Injuries, Traumatic - metabolism Brain Injuries, Traumatic - pathology Disease DNA-Binding Proteins - metabolism Energy Metabolism Humans Hypotheses Inflammation Inflammation - metabolism Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - metabolism Mutation Nervous system Neurodegeneration Neurons Neuropathology Parkinson Disease - epidemiology Parkinson Disease - metabolism Parkinson Disease - pathology Parkinson's disease Pathogens Pathology Phosphorylation Protein Aggregation, Pathological - metabolism Protein binding rab GTP-Binding Proteins - metabolism Review Risk Risk factors Studies tau Proteins - metabolism Traumatic brain injury Tremor Up-Regulation United States > US
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