Cajal body-specific small nuclear RNAs: a novel class of 2′-O-methylation and pseudouridylation guide RNAs
Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their function has remained largely speculative. Here, we describe a novel class of human small nuclear RNAs...
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| Published in: | The EMBO journal Vol. 21; no. 11; pp. 2746 - 2756 |
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| Main Authors: | , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Chichester, UK
John Wiley & Sons, Ltd
03-06-2002
Blackwell Publishing Ltd EMBO Press Oxford University Press |
| Subjects: | |
| Online Access: | Get full text |
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| Abstract | Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their function has remained largely speculative. Here, we describe a novel class of human small nuclear RNAs that localize specifically to Cajal bodies. The small Cajal body‐ specific RNAs (scaRNAs) are predicted or have already been demonstrated to function as guide RNAs in site‐specific synthesis of 2′‐O‐ribose‐methylated nucleotides and pseudouridines in the RNA polymerase II‐transcribed U1, U2, U4 and U5 spliceosomal small nuclear RNAs (snRNAs). Our results provide strong support for the idea that the Cajal body, this mysterious nuclear organelle, provides the cellular locale for post‐transcriptional modification of spliceosomal snRNAs. |
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| AbstractList | Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their function has remained largely speculative. Here, we describe a novel class of human small nuclear RNAs that localize specifically to Cajal bodies. The small Cajal body‐ specific RNAs (scaRNAs) are predicted or have already been demonstrated to function as guide RNAs in site‐specific synthesis of 2′‐O‐ribose‐methylated nucleotides and pseudouridines in the RNA polymerase II‐transcribed U1, U2, U4 and U5 spliceosomal small nuclear RNAs (snRNAs). Our results provide strong support for the idea that the Cajal body, this mysterious nuclear organelle, provides the cellular locale for post‐transcriptional modification of spliceosomal snRNAs. Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their function has remained largely speculative. Here, we describe a novel class of human small nuclear RNAs that localize specifically to Cajal bodies. The small Cajal body- specific RNAs (scaRNAs) are predicted or have already been demonstrated to function as guide RNAs in site-specific synthesis of 2′- O -ribose-methylated nucleotides and pseudouridines in the RNA polymerase II-transcribed U1, U2, U4 and U5 spliceosomal small nuclear RNAs (snRNAs). Our results provide strong support for the idea that the Cajal body, this mysterious nuclear organelle, provides the cellular locale for post-transcriptional modification of spliceosomal snRNAs. Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their function has remained largely speculative. Here, we describe a novel class of human small nuclear RNAs that localize specifically to Cajal bodies. The small Cajal body- specific RNAs (scaRNAs) are predicted or have already been demonstrated to function as guide RNAs in site-specific synthesis of 2'-O- ribose-methylated nucleotides and pseudouridines in the RNA polymeraseI-transcribed U1, U2, U4 and U5 spliceosomal small nuclear RNAs (snRNAs). Our results provide strong support for the idea that the Cajal body, this mysterious nuclear organelle, provides the cellular locale for post-transcriptional modification of spliceosomal snRNAs. |
| Author | Bertrand, Edouard Verheggen, Céline Darzacq, Xavier Jády, Beáta E. Kiss, Arnold M. Kiss, Tamás |
| AuthorAffiliation | Laboratoire de Biologie Moléculaire Eucaryote du CNRS, Université Paul Sabatier, 118 route de Narbonne, 31062 Toulouse Cedex, 2 Institut de Génétique Moléculaire, Montpellier, France and 1 Biological Research Center, Hungarian Academy of Sciences, Szeged, Hungary 3 Corresponding author e-mail: tamas@ibcg.biotoul.fr |
| AuthorAffiliation_xml | – name: Laboratoire de Biologie Moléculaire Eucaryote du CNRS, Université Paul Sabatier, 118 route de Narbonne, 31062 Toulouse Cedex, 2 Institut de Génétique Moléculaire, Montpellier, France and 1 Biological Research Center, Hungarian Academy of Sciences, Szeged, Hungary 3 Corresponding author e-mail: tamas@ibcg.biotoul.fr |
| Author_xml | – sequence: 1 givenname: Xavier surname: Darzacq fullname: Darzacq, Xavier organization: Laboratoire de Biologie Moléculaire Eucaryote du CNRS, Université Paul Sabatier, 118 route de Narbonne, Cedex, 31062, Toulouse, France – sequence: 2 givenname: Beáta E. surname: Jády fullname: Jády, Beáta E. organization: Biological Research Center, Hungarian Academy of Sciences, Szeged, Hungary – sequence: 3 givenname: Céline surname: Verheggen fullname: Verheggen, Céline organization: Institut de Génétique Moléculaire, Montpellier, France – sequence: 4 givenname: Arnold M. surname: Kiss fullname: Kiss, Arnold M. organization: Biological Research Center, Hungarian Academy of Sciences, Szeged, Hungary – sequence: 5 givenname: Edouard surname: Bertrand fullname: Bertrand, Edouard organization: Institut de Génétique Moléculaire, Montpellier, France – sequence: 6 givenname: Tamás surname: Kiss fullname: Kiss, Tamás email: tamas@ibcg.biotoul.fr organization: Laboratoire de Biologie Moléculaire Eucaryote du CNRS, Université Paul Sabatier, 118 route de Narbonne, Cedex, 31062, Toulouse, France |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/12032087$$D View this record in MEDLINE/PubMed https://hal.science/hal-02197522$$DView record in HAL |
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| ContentType | Journal Article |
| Copyright | Copyright © 2002 European Molecular Biology Organization Copyright Oxford University Press(England) Jun 03, 2002 Distributed under a Creative Commons Attribution 4.0 International License Copyright © 2002 European Molecular Biology Organization 2002 |
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| Keywords | cajal body rna modification scarna spliceosomal snrna snorna small nucleolar rnas u6 spliceosomal rna pre-ribosomal-rna box-c/d motif coiled bodies 2'-o-ribose methylation preribosomal rna u5 snrnps u2 snrna localization |
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| References | Jády BE and Kiss T (2001) A small nucleolar guide RNA functions both in 2′-O-ribose methylation and pseudouridylation of the U5 spliceosomal RNA. EMBO J, 20, 541-551. Narayanan A, Lukowiak A, Jády BE, Dragon F, Kiss T, Terns RM and Terns MP (1999a) Nucleolar localization signals of box H/ACA small nucleolar RNAs. EMBO J, 18, 5120-5130. Wang H, Boisvert D, Kim KK, Kim R and Kim SH (2000) Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 Å resolution. EMBO J, 19, 317-323. Kiss T and Filipowicz W (1995) Exonucleolytic processing of small nucleolar RNAs from pre-mRNA introns. Genes Dev, 9, 1411-1424. Will CL and Lührmann R (2001) Spliceosomal UsnRNP biogenesis, structure and function. Curr Opin Cell Biol, 13, 290-301. Kiss T (2001) Small nucleolar RNA-guided post-transcriptional modification of cellular RNAs. EMBO J, 20, 3617-3622. Matera AG (1998) Of coiled bodies, gems, and salmon. J Cell Biochem, 70, 181-192. Ni J, Tien AL and Fournier MJ (1997) Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA. Cell, 89, 565-573. Yu YT, Shu MD, Narayanan A, Terns RM, Terns MP and Steitz JA (2001) Internal modification of U2 small nuclear (sn)RNA occurs in nucleoli of Xenopus oocytes. J Cell Biol, 152, 1279-1288. Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP and Brosius J (2001) RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse. EMBO J, 20, 2943-2953. Lyon CE, Bohmann K, Sleeman J and Lamond AI (1997) Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus. Exp Cell Res, 230, 84-93. Sleeman JE and Lamond AI (1999b) Nuclear organization of pre-mRNA splicing factors. Curr Opin Cell Biol, 11, 372-377. Spector DL (1993) Macromolecular domains within the cell nucleus. Annu Rev Cell Biol, 9, 265-315. Tyc K and Steitz JA (1989) U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus. EMBO J, 8, 3113-3119. Kiss-László Z, Henry Y, Bachellerie J-P, Caizergues-Ferrer M and Kiss T (1996) Site-specific ribose methylation of preribosomal RNA: A novel function for small nucleolar RNAs. Cell, 85, 1077-1088. Narayanan A, Speckmann W, Terns R and Terns MP (1999b) Role of the box C/D motif in localization of small nucleolar RNAs to coiled bodies and nucleoli. Mol Biol Cell, 10, 2131-2147. Andrade LE, Chan EK, Raska I, Peebles CL, Roos G and Tan EM (1991) Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin. J Exp Med, 173, 1407-1419. Matera AG (1999) Nuclear bodies: multifaceted subdomains of the interchromatin space. Trends Cell Biol, 9, 302-309. Samarsky DA, Fournier MJ, Singer RH and Bertrand E (1998) The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization. EMBO J, 17, 3747-3757. Ganot P, Jády BE, Bortolin M-L, Darzacq X and Kiss T (1999) Nucleolar factors direct the 2′-O-ribose methylation and pseudouridylation of U6 spliceosomal RNA. Mol Cell Biol, 19, 6906-6917. Smith CM and Steitz JA (1997) Sno storm in the nucleolus: new roles for myriad small RNPs. Cell, 89, 669-672. Zebarjadian Y, King T, Fournier MJ, Clarke L and Carbon J (1999) Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA. Mol Cell Biol, 19, 7461-7472. Ségault V, Will CL, Sproat BS and Lührmann R (1995) In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs. EMBO J, 14, 4010-4021. Tollervey D, Lehtonen H, Jansen R, Kern H and Hurt EC (1993) Temperature-sensitive mutations demonstrate roles for yeast fibrillarin in pre-rRNA processing, pre-rRNA methylation, and ribosome assembly. Cell, 72, 443-457. Weinstein LB and Steitz JA (1999) Guided tours: from precursor snoRNA to functional snoRNP. Curr Opin Cell Biol, 11, 378-384. Kiss-László Z, Henry Y and Kiss T (1998) Sequence and structural elements of methylation guide snoRNAs essential for site-specific ribose methylation of pre-rRNA. EMBO J, 17, 797-807. Pan ZQ and Prives C (1989) U2 snRNA sequences that bind U2-specific proteins are dispensable for the function of U2 snRNP in splicing. Genes Dev, 3, 1887-1898. Lamond AI and Earnshaw WC (1998) Structure and function in the nucleus. Science, 280, 547-553. Ganot P, Caizergues-Ferrer M and Kiss T (1997b) The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes Dev, 11, 941-956. Matera AG and Ward DC (1993) Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells. J Cell Biol, 121, 715-727. Lafontaine DL, Bousquet-Antonelli C, Henry Y, Caizergues-Ferrer M and Tollervey D (1998) The box H+ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase. Genes Dev, 12, 527-537. Carmo-Fonseca M, Pepperkok R, Carvalho MT and Lamond AI (1992) Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies. J Cell Biol, 117, 1-14. Lange TS and Gerbi SA (2000) Transient nucleolar localization of U6 small nuclear RNA in Xenopus laevis oocytes. Mol Biol Cell, 11, 2419-2428. Lewis JD and Tollervey D (2000) Like attracts like: getting RNA processing together in the nucleus. Science, 288, 1385-1389. Cavaillé J, Nicoloso M and Bachellerie JP (1996) Targeted ribose methylation of RNA in vivo directed by tailored antisense RNA guides. Nature, 383, 732-735. Tollervey D and Kiss T (1997) Function and synthesis of small nucleolar RNAs. Curr Opin Cell Biol, 9, 337-342. Balakin AG, Smith L and Fournier MJ (1996) The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell, 86, 823-834. Gall JG (2000) Cajal bodies: the first 100 years. Annu Rev Cell Dev Biol, 16, 273-300. Smith KP and Lawrence JB (2000) Interactions of U2 gene loci and their nuclear transcripts with Cajal (coiled) bodies: Evidence for preU2 within Cajal bodies. Mol Biol Cell, 11, 2987-2998. Bohmann K, Ferreira J, Santama N, Weis K and Lamond AI (1995) Molecular analysis of the coiled body. J Cell Sci, 19, Suppl., 107-113. Sleeman JE and Lamond AI (1999a) Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Curr Biol, 9, 1065-1074. Goodall GJ, Wiebauer K and Filipowicz W (1990) Analysis of pre-mRNA processing in transfected plant protoplasts. Methods Enzymol, 181, 148-161. Tycowski KT, You ZH, Graham PJ and Steitz JA (1998) Modification of U6 spliceosomal RNA is guided by other small RNAs. Mol Cell, 2, 629-638. Ganot P, Bortolin M-L and Kiss T (1997a) Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. Cell, 89, 799-809. Yu YT, Shu MD and Steitz JA (1998) Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing. EMBO J, 17, 5783-5795. Lange TS, Borovjagin A, Maxwell ES and Gerbi SA (1998) Conserved boxes C and D are essential nucleolar localization elements of U14 and U8 snoRNAs. EMBO J, 17, 3176-3187. Sambrook J, Fritsch EF and Maniatis T (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. Carvalho T, Almeida F, Calapez A, Lafarga M, Berciano MT and Carmo-Fonseca M (1999) The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body. J Cell Biol, 147, 715-728. Lyon, CE, Bohmann, K, Sleeman, J, Lamond, AI (b25) 1997; 230 Spector, DL (b42) 1993; 9 Jády, BE, Kiss, T (b15) 2001; 20 Lafontaine, DL, Bousquet-Antonelli, C, Henry, Y, Caizergues-Ferrer, M, Tollervey, D (b20) 1998; 12 Sleeman, JE, Lamond, AI (b38) 1999a; 9 Smith, KP, Lawrence, JB (b40) 2000; 11 Goodall, GJ, Wiebauer, K, Filipowicz, W (b13) 1990; 181 Tycowski, KT, You, ZH, Graham, PJ, Steitz, JA (b46) 1998; 2 Ganot, P, Jády, BE, Bortolin, M-L, Darzacq, X, Kiss, T (b11) 1999; 19 Ganot, P, Caizergues-Ferrer, M, Kiss, T (b10) 1997b; 11 Matera, AG, Ward, DC (b29) 1993; 121 Samarsky, DA, Fournier, MJ, Singer, RH, Bertrand, E (b35) 1998; 17 Ganot, P, Bortolin, M-L, Kiss, T (b9) 1997a; 89 Wang, H, Boisvert, D, Kim, KK, Kim, R, Kim, SH (b47) 2000; 19 Lange, TS, Borovjagin, A, Maxwell, ES, Gerbi, SA (b23) 1998; 17 Lange, TS, Gerbi, SA (b22) 2000; 11 Kiss, T (b16) 2001; 20 Pan, ZQ, Prives, C (b33) 1989; 3 Carmo-Fonseca, M, Pepperkok, R, Carvalho, MT, Lamond, AI (b5) 1992; 117 Massenet, S, Mougin, A, Branlant, C (b26) 1998 Matera, AG (b27) 1998; 70 Ségault, V, Will, CL, Sproat, BS, Lührmann, R (b37) 1995; 14 Bohmann, K, Ferreira, J, Santama, N, Weis, K, Lamond, AI (b3) 1995; 19 Smith, CM, Steitz, JA (b41) 1997; 89 Kiss-László, Z, Henry, Y, Kiss, T (b19) 1998; 17 Andrade, LE, Chan, EK, Raska, I, Peebles, CL, Roos, G, Tan, EM (b1) 1991; 173 Will, CL, Lührmann, R (b49) 2001; 13 Matera, AG (b28) 1999; 9 Ni, J, Tien, AL, Fournier, MJ (b32) 1997; 89 Kiss, T, Filipowicz, W (b17) 1995; 9 Yu, YT, Shu, MD, Narayanan, A, Terns, RM, Terns, MP, Steitz, JA (b51) 2001; 152 Tyc, K, Steitz, JA (b45) 1989; 8 Zebarjadian, Y, King, T, Fournier, MJ, Clarke, L, Carbon, J (b52) 1999; 19 Sambrook, J, Fritsch, EF, Maniatis, T (b36) 1989 Cavaillé, J, Nicoloso, M, Bachellerie, JP (b7) 1996; 383 Tollervey, D, Lehtonen, H, Jansen, R, Kern, H, Hurt, EC (b44) 1993; 72 Kiss-László, Z, Henry, Y, Bachellerie, J-P, Caizergues-Ferrer, M, Kiss, T (b18) 1996; 85 Lamond, AI, Earnshaw, WC (b21) 1998; 280 Yu, YT, Shu, MD, Steitz, JA (b50) 1998; 17 Burge, CB, Tuschl, T, Sharp, PA (b4) 1999 Gall, JG (b8) 2000; 16 Narayanan, A, Speckmann, W, Terns, R, Terns, MP (b31) 1999b; 10 Carvalho, T, Almeida, F, Calapez, A, Lafarga, M, Berciano, MT, Carmo-Fonseca, M (b6) 1999; 147 Tollervey, D, Kiss, T (b43) 1997; 9 Hüttenhofer, A, Kiefmann, M, Meier-Ewert, S, O'Brien, J, Lehrach, H, Bachellerie, JP, Brosius, J (b14) 2001; 20 Narayanan, A, Lukowiak, A, Jády, BE, Dragon, F, Kiss, T, Terns, RM, Terns, MP (b30) 1999a; 18 Balakin, AG, Smith, L, Fournier, MJ (b2) 1996; 86 Lewis, JD, Tollervey, D (b24) 2000; 288 Weinstein, LB, Steitz, JA (b48) 1999; 11 Sleeman, JE, Lamond, AI (b39) 1999b; 11 Reddy, R, Busch, H (b34) 1988 1989; 3 1995; 9 1993; 9 1991; 173 1998; 280 1995; 14 1997; 230 1997; 89 1989; 8 1990; 181 1998 1999; 147 1995; 19 1996; 383 1997b; 11 1993; 121 1997; 9 2001; 20 1999 1999; 9 1998; 17 2000; 19 2000; 16 2001; 152 1993; 72 1999; 19 1999a; 9 1997a; 89 2000; 11 1999a; 18 1992; 117 1996; 85 1999; 11 1998; 70 1998; 2 2000; 288 2001; 13 1998; 12 1999b; 11 1996; 86 1999b; 10 1989 1988 2033369 - J Exp Med. 1991 Jun 1;173(6):1407-19 9013710 - Exp Cell Res. 1997 Jan 10;230(1):84-93 9472021 - Genes Dev. 1998 Feb 15;12(4):527-37 10531003 - Curr Biol. 1999 Oct 7;9(19):1065-74 1532583 - J Cell Biol. 1992 Apr;117(1):1-14 11257127 - J Cell Biol. 2001 Mar 19;152(6):1279-88 11447102 - EMBO J. 2001 Jul 16;20(14):3617-22 9671224 - J Cell Biochem. 1998 Aug 1;70(2):181-92 10490628 - Mol Cell Biol. 1999 Oct;19(10):6906-17 10888678 - Mol Biol Cell. 2000 Jul;11(7):2419-28 8878486 - Nature. 1996 Oct 24;383(6602):732-5 9159079 - Curr Opin Cell Biol. 1997 Jun;9(3):337-42 10523634 - Mol Cell Biol. 1999 Nov;19(11):7461-72 7797080 - Genes Dev. 1995 Jun 1;9(11):1411-24 9755178 - EMBO J. 1998 Oct 1;17(19):5783-95 9182768 - Cell. 1997 May 30;89(5):799-809 10397754 - Mol Biol Cell. 1999 Jul;10(7):2131-47 10407409 - Trends Cell Biol. 1999 Aug;9(8):302-9 10827942 - Science. 2000 May 26;288(5470):1385-9 8655641 - J Cell Sci Suppl. 1995;19:107-13 9160748 - Cell. 1997 May 16;89(4):565-73 2531075 - EMBO J. 1989 Oct;8(10):3113-9 8797828 - Cell. 1996 Sep 6;86(5):823-34 9554838 - Science. 1998 Apr 24;280(5363):547-53 11387227 - EMBO J. 2001 Jun 1;20(11):2943-53 8674114 - Cell. 1996 Jun 28;85(7):1077-88 1696344 - Methods Enzymol. 1990;181:148-61 9106664 - Genes Dev. 1997 Apr 1;11(7):941-56 11031238 - Annu Rev Cell Dev Biol. 2000;16:273-300 8431947 - Cell. 1993 Feb 12;72(3):443-57 10395556 - Curr Opin Cell Biol. 1999 Jun;11(3):372-7 10562276 - J Cell Biol. 1999 Nov 15;147(4):715-28 7664740 - EMBO J. 1995 Aug 15;14(16):4010-21 2559872 - Genes Dev. 1989 Dec;3(12A):1887-98 9844635 - Mol Cell. 1998 Nov;2(5):629-38 9182752 - Cell. 1997 May 30;89(5):669-72 10487763 - EMBO J. 1999 Sep 15;18(18):5120-30 10654930 - EMBO J. 2000 Feb 1;19(3):317-23 11157760 - EMBO J. 2001 Feb 1;20(3):541-51 10395551 - Curr Opin Cell Biol. 1999 Jun;11(3):378-84 9451004 - EMBO J. 1998 Feb 2;17(3):797-807 10982395 - Mol Biol Cell. 2000 Sep;11(9):2987-98 9649444 - EMBO J. 1998 Jul 1;17(13):3747-57 8491767 - J Cell Biol. 1993 May;121(4):715-27 9606199 - EMBO J. 1998 Jun 1;17(11):3176-87 11343899 - Curr Opin Cell Biol. 2001 Jun;13(3):290-301 8280462 - Annu Rev Cell Biol. 1993;9:265-315 |
| References_xml | – volume: 11 start-page: 2987 year: 2000 end-page: 2998 ident: b40 publication-title: Mol Biol Cell contributor: fullname: Lawrence, JB – volume: 121 start-page: 715 year: 1993 end-page: 727 ident: b29 publication-title: J Cell Biol contributor: fullname: Ward, DC – volume: 86 start-page: 823 year: 1996 end-page: 834 ident: b2 publication-title: Cell contributor: fullname: Fournier, MJ – volume: 280 start-page: 547 year: 1998 end-page: 553 ident: b21 publication-title: Science contributor: fullname: Earnshaw, WC – volume: 17 start-page: 797 year: 1998 end-page: 807 ident: b19 publication-title: EMBO J contributor: fullname: Kiss, T – volume: 19 start-page: 107 issue: Suppl year: 1995 end-page: 113 ident: b3 publication-title: J Cell Sci contributor: fullname: Lamond, AI – volume: 117 start-page: 1 year: 1992 end-page: 14 ident: b5 publication-title: J Cell Biol contributor: fullname: Lamond, AI – volume: 70 start-page: 181 year: 1998 end-page: 192 ident: b27 publication-title: J Cell Biochem contributor: fullname: Matera, AG – volume: 19 start-page: 317 year: 2000 end-page: 323 ident: b47 publication-title: EMBO J contributor: fullname: Kim, SH – volume: 181 start-page: 148 year: 1990 end-page: 161 ident: b13 publication-title: Methods Enzymol contributor: fullname: Filipowicz, W – volume: 17 start-page: 3747 year: 1998 end-page: 3757 ident: b35 publication-title: EMBO J contributor: fullname: Bertrand, E – volume: 18 start-page: 5120 year: 1999a end-page: 5130 ident: b30 publication-title: EMBO J contributor: fullname: Terns, MP – volume: 11 start-page: 2419 year: 2000 end-page: 2428 ident: b22 publication-title: Mol Biol Cell contributor: fullname: Gerbi, SA – volume: 12 start-page: 527 year: 1998 end-page: 537 ident: b20 publication-title: Genes Dev contributor: fullname: Tollervey, D – volume: 14 start-page: 4010 year: 1995 end-page: 4021 ident: b37 publication-title: EMBO J contributor: fullname: Lührmann, R – volume: 9 start-page: 265 year: 1993 end-page: 315 ident: b42 publication-title: Annu Rev Cell Biol contributor: fullname: Spector, DL – volume: 20 start-page: 541 year: 2001 end-page: 551 ident: b15 publication-title: EMBO J contributor: fullname: Kiss, T – volume: 3 start-page: 1887 year: 1989 end-page: 1898 ident: b33 publication-title: Genes Dev contributor: fullname: Prives, C – volume: 16 start-page: 273 year: 2000 end-page: 300 ident: b8 publication-title: Annu Rev Cell Dev Biol contributor: fullname: Gall, JG – volume: 11 start-page: 378 year: 1999 end-page: 384 ident: b48 publication-title: Curr Opin Cell Biol contributor: fullname: Steitz, JA – volume: 383 start-page: 732 year: 1996 end-page: 735 ident: b7 publication-title: Nature contributor: fullname: Bachellerie, JP – volume: 11 start-page: 372 year: 1999b end-page: 377 ident: b39 publication-title: Curr Opin Cell Biol contributor: fullname: Lamond, AI – volume: 288 start-page: 1385 year: 2000 end-page: 1389 ident: b24 publication-title: Science contributor: fullname: Tollervey, D – year: 1989 ident: b36 article-title: Molecular Cloning: A Laboratory Manual contributor: fullname: Maniatis, T – volume: 72 start-page: 443 year: 1993 end-page: 457 ident: b44 publication-title: Cell contributor: fullname: Hurt, EC – volume: 19 start-page: 7461 year: 1999 end-page: 7472 ident: b52 publication-title: Mol Cell Biol contributor: fullname: Carbon, J – volume: 11 start-page: 941 year: 1997b end-page: 956 ident: b10 publication-title: Genes Dev contributor: fullname: Kiss, T – start-page: 201 year: 1998 end-page: 227 ident: b26 article-title: Modification and Editing of RNA contributor: fullname: Branlant, C – volume: 9 start-page: 337 year: 1997 end-page: 342 ident: b43 publication-title: Curr Opin Cell Biol contributor: fullname: Kiss, T – volume: 89 start-page: 565 year: 1997 end-page: 573 ident: b32 publication-title: Cell contributor: fullname: Fournier, MJ – volume: 9 start-page: 1065 year: 1999a end-page: 1074 ident: b38 publication-title: Curr Biol contributor: fullname: Lamond, AI – volume: 89 start-page: 799 year: 1997a end-page: 809 ident: b9 publication-title: Cell contributor: fullname: Kiss, T – volume: 152 start-page: 1279 year: 2001 end-page: 1288 ident: b51 publication-title: J Cell Biol contributor: fullname: Steitz, JA – start-page: 525 year: 1999 end-page: 560 ident: b4 article-title: The RNA World contributor: fullname: Sharp, PA – volume: 2 start-page: 629 year: 1998 end-page: 638 ident: b46 publication-title: Mol Cell contributor: fullname: Steitz, JA – volume: 230 start-page: 84 year: 1997 end-page: 93 ident: b25 publication-title: Exp Cell Res contributor: fullname: Lamond, AI – volume: 13 start-page: 290 year: 2001 end-page: 301 ident: b49 publication-title: Curr Opin Cell Biol contributor: fullname: Lührmann, R – volume: 85 start-page: 1077 year: 1996 end-page: 1088 ident: b18 publication-title: Cell contributor: fullname: Kiss, T – volume: 8 start-page: 3113 year: 1989 end-page: 3119 ident: b45 publication-title: EMBO J contributor: fullname: Steitz, JA – volume: 9 start-page: 302 year: 1999 end-page: 309 ident: b28 publication-title: Trends Cell Biol contributor: fullname: Matera, AG – volume: 9 start-page: 1411 year: 1995 end-page: 1424 ident: b17 publication-title: Genes Dev contributor: fullname: Filipowicz, W – volume: 173 start-page: 1407 year: 1991 end-page: 1419 ident: b1 publication-title: J Exp Med contributor: fullname: Tan, EM – volume: 147 start-page: 715 year: 1999 end-page: 728 ident: b6 publication-title: J Cell Biol contributor: fullname: Carmo-Fonseca, M – volume: 17 start-page: 3176 year: 1998 end-page: 3187 ident: b23 publication-title: EMBO J contributor: fullname: Gerbi, SA – volume: 20 start-page: 2943 year: 2001 end-page: 2953 ident: b14 publication-title: EMBO J contributor: fullname: Brosius, J – volume: 89 start-page: 669 year: 1997 end-page: 672 ident: b41 publication-title: Cell contributor: fullname: Steitz, JA – volume: 10 start-page: 2131 year: 1999b end-page: 2147 ident: b31 publication-title: Mol Biol Cell contributor: fullname: Terns, MP – volume: 17 start-page: 5783 year: 1998 end-page: 5795 ident: b50 publication-title: EMBO J contributor: fullname: Steitz, JA – volume: 20 start-page: 3617 year: 2001 end-page: 3622 ident: b16 publication-title: EMBO J contributor: fullname: Kiss, T – volume: 19 start-page: 6906 year: 1999 end-page: 6917 ident: b11 publication-title: Mol Cell Biol contributor: fullname: Kiss, T – start-page: 1 year: 1988 end-page: 37 ident: b34 article-title: Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles contributor: fullname: Busch, H – volume: 173 start-page: 1407 year: 1991 end-page: 1419 article-title: Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80‐coilin publication-title: J Exp Med – volume: 11 start-page: 378 year: 1999 end-page: 384 article-title: Guided tours: from precursor snoRNA to functional snoRNP publication-title: Curr Opin Cell Biol – volume: 117 start-page: 1 year: 1992 end-page: 14 article-title: Transcription‐dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies publication-title: J Cell Biol – year: 1989 – volume: 9 start-page: 265 year: 1993 end-page: 315 article-title: Macromolecular domains within the cell nucleus publication-title: Annu Rev Cell Biol – start-page: 1 year: 1988 end-page: 37 article-title: Small nuclear RNAs: RNA sequences, structure, and modifications – volume: 11 start-page: 2419 year: 2000 end-page: 2428 article-title: Transient nucleolar localization of U6 small nuclear RNA in oocytes publication-title: Mol Biol Cell – volume: 19 start-page: 317 year: 2000 end-page: 323 article-title: Crystal structure of a fibrillarin homologue from , a hyperthermophile, at 1.6 Å resolution publication-title: EMBO J – volume: 11 start-page: 372 year: 1999b end-page: 377 article-title: Nuclear organization of pre‐mRNA splicing factors publication-title: Curr Opin Cell Biol – volume: 9 start-page: 302 year: 1999 end-page: 309 article-title: Nuclear bodies: multifaceted subdomains of the interchromatin space publication-title: Trends Cell Biol – volume: 10 start-page: 2131 year: 1999b end-page: 2147 article-title: Role of the box C/D motif in localization of small nucleolar RNAs to coiled bodies and nucleoli publication-title: Mol Biol Cell – start-page: 525 year: 1999 end-page: 560 article-title: Splicing of precursors to mRNAs by the spliceosome – volume: 288 start-page: 1385 year: 2000 end-page: 1389 article-title: Like attracts like: getting RNA processing together in the nucleus publication-title: Science – volume: 20 start-page: 3617 year: 2001 end-page: 3622 article-title: Small nucleolar RNA‐guided post‐transcriptional modification of cellular RNAs publication-title: EMBO J – volume: 8 start-page: 3113 year: 1989 end-page: 3119 article-title: U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus publication-title: EMBO J – volume: 230 start-page: 84 year: 1997 end-page: 93 article-title: Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus publication-title: Exp Cell Res – volume: 89 start-page: 565 year: 1997 end-page: 573 article-title: Small nucleolar RNAs direct site‐specific synthesis of pseudouridine in ribosomal RNA publication-title: Cell – volume: 121 start-page: 715 year: 1993 end-page: 727 article-title: Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells publication-title: J Cell Biol – volume: 12 start-page: 527 year: 1998 end-page: 537 article-title: The box H+ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase publication-title: Genes Dev – volume: 9 start-page: 1065 year: 1999a end-page: 1074 article-title: Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway publication-title: Curr Biol – volume: 17 start-page: 3747 year: 1998 end-page: 3757 article-title: The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization publication-title: EMBO J – volume: 17 start-page: 3176 year: 1998 end-page: 3187 article-title: Conserved boxes C and D are essential nucleolar localization elements of U14 and U8 snoRNAs publication-title: EMBO J – volume: 89 start-page: 669 year: 1997 end-page: 672 article-title: Sno storm in the nucleolus: new roles for myriad small RNPs publication-title: Cell – volume: 19 start-page: 7461 year: 1999 end-page: 7472 article-title: Point mutations in yeast CBF5 can abolish pseudouridylation of rRNA publication-title: Mol Cell Biol – volume: 13 start-page: 290 year: 2001 end-page: 301 article-title: Spliceosomal UsnRNP biogenesis, structure and function publication-title: Curr Opin Cell Biol – volume: 383 start-page: 732 year: 1996 end-page: 735 article-title: Targeted ribose methylation of RNA directed by tailored antisense RNA guides publication-title: Nature – volume: 18 start-page: 5120 year: 1999a end-page: 5130 article-title: Nucleolar localization signals of box H/ACA small nucleolar RNAs publication-title: EMBO J – volume: 3 start-page: 1887 year: 1989 end-page: 1898 article-title: U2 snRNA sequences that bind U2‐specific proteins are dispensable for the function of U2 snRNP in splicing publication-title: Genes Dev – volume: 89 start-page: 799 year: 1997a end-page: 809 article-title: Site‐specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs publication-title: Cell – volume: 2 start-page: 629 year: 1998 end-page: 638 article-title: Modification of U6 spliceosomal RNA is guided by other small RNAs publication-title: Mol Cell – volume: 181 start-page: 148 year: 1990 end-page: 161 article-title: Analysis of pre‐mRNA processing in transfected plant protoplasts publication-title: Methods Enzymol – volume: 11 start-page: 941 year: 1997b end-page: 956 article-title: The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation publication-title: Genes Dev – volume: 280 start-page: 547 year: 1998 end-page: 553 article-title: Structure and function in the nucleus publication-title: Science – volume: 14 start-page: 4010 year: 1995 end-page: 4021 article-title: reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs publication-title: EMBO J – volume: 85 start-page: 1077 year: 1996 end-page: 1088 article-title: Site‐specific ribose methylation of preribosomal RNA: A novel function for small nucleolar RNAs publication-title: Cell – volume: 17 start-page: 5783 year: 1998 end-page: 5795 article-title: Modifications of U2 snRNA are required for snRNP assembly and pre‐mRNA splicing publication-title: EMBO J – start-page: 201 year: 1998 end-page: 227 article-title: Posttranscriptional modifications in the U small nuclear RNAs – volume: 86 start-page: 823 year: 1996 end-page: 834 article-title: The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions publication-title: Cell – volume: 16 start-page: 273 year: 2000 end-page: 300 article-title: Cajal bodies: the first 100 years publication-title: Annu Rev Cell Dev Biol – volume: 70 start-page: 181 year: 1998 end-page: 192 article-title: Of coiled bodies, gems, and salmon publication-title: J Cell Biochem – volume: 72 start-page: 443 year: 1993 end-page: 457 article-title: Temperature‐sensitive mutations demonstrate roles for yeast fibrillarin in pre‐rRNA processing, pre‐rRNA methylation, and ribosome assembly publication-title: Cell – volume: 11 start-page: 2987 year: 2000 end-page: 2998 article-title: Interactions of U2 gene loci and their nuclear transcripts with Cajal (coiled) bodies: Evidence for preU2 within Cajal bodies publication-title: Mol Biol Cell – volume: 19 start-page: 107 year: 1995 end-page: 113 article-title: Molecular analysis of the coiled body publication-title: J Cell Sci – volume: 20 start-page: 541 year: 2001 end-page: 551 article-title: A small nucleolar guide RNA functions both in 2′‐ ‐ribose methylation and pseudouridylation of the U5 spliceosomal RNA publication-title: EMBO J – volume: 19 start-page: 6906 year: 1999 end-page: 6917 article-title: Nucleolar factors direct the 2′‐ ‐ribose methylation and pseudouridylation of U6 spliceosomal RNA publication-title: Mol Cell Biol – volume: 152 start-page: 1279 year: 2001 end-page: 1288 article-title: Internal modification of U2 small nuclear (sn)RNA occurs in nucleoli of oocytes publication-title: J Cell Biol – volume: 9 start-page: 1411 year: 1995 end-page: 1424 article-title: Exonucleolytic processing of small nucleolar RNAs from pre‐mRNA introns publication-title: Genes Dev – volume: 147 start-page: 715 year: 1999 end-page: 728 article-title: The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body publication-title: J Cell Biol – volume: 9 start-page: 337 year: 1997 end-page: 342 article-title: Function and synthesis of small nucleolar RNAs publication-title: Curr Opin Cell Biol – volume: 17 start-page: 797 year: 1998 end-page: 807 article-title: Sequence and structural elements of methylation guide snoRNAs essential for site‐specific ribose methylation of pre‐rRNA publication-title: EMBO J – volume: 20 start-page: 2943 year: 2001 end-page: 2953 article-title: RNomics: an experimental approach that identifies 201 candidates for novel, small, non‐messenger RNAs in mouse publication-title: EMBO J |
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| Snippet | Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first... |
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| SubjectTerms | Animals Base Sequence Biochemistry, Molecular Biology Cajal bodies Cajal body Cell Nucleus - metabolism Coiled Bodies - metabolism Coiled Bodies - physiology DNA, Complementary - metabolism HeLa Cells Humans In Situ Hybridization In Situ Hybridization, Fluorescence Life Sciences Methylation Models, Genetic Molecular Sequence Data Nucleic Acid Conformation Oocytes - metabolism Plasmids - metabolism Precipitin Tests Protein Binding RNA - metabolism RNA modification RNA, Small Nuclear - metabolism scaRNA snoRNA snRNA spliceosomal snRNA Spliceosomes - metabolism Subcellular Fractions - metabolism Transcription, Genetic Uridine Monophosphate - metabolism Xenopus |
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| Title | Cajal body-specific small nuclear RNAs: a novel class of 2′-O-methylation and pseudouridylation guide RNAs |
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