Evaluating Differences in Whole Blood, Serum, and Urine Screening Tests for Zika Virus, Puerto Rico, USA, 2016

• Published in: Emerging infectious diseases Vol. 27; no. 5; pp. 1505 - 1508
• Main Authors: Rosinger, Asher Y, Olson, Samantha M, Ellington, Sascha R, Perez-Padilla, Janice, Simeone, Regina M, Pedati, Caitlin S, Schroeder, Betsy A, Santiago, Gilberto A, Medina, Freddy A, Muñoz-Jordán, Jorge L, Adams, Laura E, Galang, Romeo R, Valencia-Prado, Miguel, Bakkour, Sonia, Colón, Candimar, Goodwin, Mary, Meaney-Delman, Dana, Read, Jennifer S, Petersen, Lyle R, Jamieson, Denise J, Deseda, Carmen C, Honein, Margaret A, Rivera-García, Brenda, Shapiro-Mendoza, Carrie K
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01-05-2021; Centers for Disease Control and Prevention
• Subjects: Analysis; Asymptomatic; Blood; Comparative analysis; Disease control; Disease prevention; Dispatch; Epidemics; Evaluating Differences in Whole Blood, Serum, and Urine Screening Tests for Zika Virus, Puerto Rico, 2016; Infections; Influenza; Medical examination; Medical laboratories; Medical screening; Methods; Nucleic acids; outbreak; PCR; Pregnancy; Puerto Rico; Serodiagnosis; Severe acute respiratory syndrome coronavirus 2; Testing; Urine; Vector-borne diseases; whole blood; Womens health; Zika virus; Puerto Rico; United States > US; NAAT; Puerto Rico; mosquito-borne diseases; viruses; United States; vector-borne diseases; pregnancy; whole blood; zoonoses; Zika virus; mosquitos; outbreak; nucleic acid amplification testing; PCR
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2705.203960

We evaluated nucleic acid amplification testing (NAAT) for Zika virus on whole-blood specimens compared with NAAT on serum and urine specimens among asymptomatic pregnant women during the 2015-2016 Puerto Rico Zika outbreak. Using NAAT, more infections were detected in serum and urine than in whole blood specimens.