Potential survival benefits from optimized chemotherapy implementation in advanced ovarian cancer: Projections from a microsimulation model

Ovarian cancer is often diagnosed in advanced stages, when survival is poor. Treatment advances have been made, but are inconsistently implemented. Our purpose was to project the maximum life expectancy gains that could be achieved in women with stage IIIC epithelial ovarian cancer if the implementa...

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Bibliographic Details
Published in:	PloS one Vol. 14; no. 9; p. e0222828
Main Authors:	Lietz, Anna P, Weaver, Davis T, Melamed, Alexander, Rauh-Hain, Jose Alejandro, Wright, Jason D, Wright, Alexi A, Knudsen, Amy B, Pandharipande, Pari V
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 20-09-2019 Public Library of Science (PLoS)
Subjects:	Adjuvant chemotherapy Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bevacizumab Bevacizumab - administration & dosage Biology and Life Sciences Cancer Cancer therapies Cancer treatment Care and treatment Chemotherapy Combined Modality Therapy Computer simulation Cytoreduction Surgical Procedures - methods Debulking Diagnosis Disease-Free Survival Drug dosages Drug Therapy - methods Female Gynecology Hospitals Humans Intravenous administration Kaplan-Meier Estimate Life expectancy Life span Medical prognosis Medicine and Health Sciences Middle Aged Monoclonal antibodies Obstetrics Oncology Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - drug therapy Ovarian Neoplasms - surgery Patients Physical Sciences Research and Analysis Methods Retirement benefits Sensitivity analysis Surgery Survival Targeted cancer therapy Womens health United States > US Massachusetts
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