1254-P: Genetic Prediction of C-Peptide Trajectory before Type 1 Diabetes Diagnosis in TrialNet

Modeling the course of C-peptide decline in autoantibody (Ab) positive individuals is important for type 1 diabetes (T1D) prediction and implementation of T1D prevention trials. Single nucleotide polymorphisms in TCF7L2, JAZF1, SLC30A8, INS, PTPRK, G6CP2, CLEC16, PTPN22 and HLA genes are associated...

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Bibliographic Details

Published in:	Diabetes (New York, N.Y.) Vol. 71; no. Supplement_1
Main Authors:	TRIOLO, TAYLOR M., PARIKH, HEMANG M., TOSUR, MUSTAFA, GOTTLIEB, PETER, ORAM, RICHARD A., ONENGUT-GUMUSCU, SUNA, KRISCHER, JEFFREY, RICH, STEPHEN S., STECK, ANDREA, REDONDO, MARIA J.
Format:	Journal Article
Language:	English
Published:	New York American Diabetes Association 01-06-2022
Subjects:	Autoantibodies Clinical trials Diabetes Diabetes mellitus (insulin dependent) Diabetes mellitus (non-insulin dependent) Diagnosis Haplotypes Histocompatibility antigen HLA Medical diagnosis Peptides Protein-tyrosine-phosphatase Single-nucleotide polymorphism
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