Identification of a taurine transport inhibitory substance in sesame seeds

An ethanol extract from sesame seeds inhibited the taurine uptake in human intestinal epithelial Caco-2 cells. The uptake of such α-amino acids as leucine and glutamic acid was not inhibited by the extract, indicating that this inhibition is specific to the taurine uptake. The unknown inhibitor in t...

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Bibliographic Details
Published in:	Bioscience, biotechnology, and biochemistry Vol. 64; no. 6; pp. 1166 - 1172
Main Authors:	Ishizuka, K. (Tokyo Univ. (Japan)), Kanayama, A, Satsu, H, Miyamoto, Y, Furihata, K, Shimizu, M
Format:	Journal Article
Language:	English
Published:	Tokyo Japan Society for Bioscience, Biotechnology, and Agrochemistry 01-06-2000 Japan Society for Bioscience Biotechnology and Agrochemistry Oxford University Press
Subjects:	Biological and medical sciences Biological Transport, Active - drug effects BLOOD CIRCULATION Caco-2 Caco-2 Cells EXTRACTS Food Analysis Fundamental and applied biological sciences. Psychology Humans INHIBITION Intestine. Mesentery INTESTINES Intestines - drug effects Intestines - metabolism Kinetics LYSOPHOSPHATIDYLCHOLINE Lysophosphatidylcholines - isolation & purification Lysophosphatidylcholines - pharmacology Lysophosphatidylcholines - toxicity MANKIND Plant Extracts - isolation & purification Plant Extracts - pharmacology Seeds - chemistry SESAME TAURINE Taurine - metabolism transporter Vertebrates: digestive system Human Taurine Digestive system Biological transport Gut Extract Foodstuff Lysophosphatidylcholine Sesame seed Cell line Plant origin Colon Inhibition
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