Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease

Obesity is a particularly complex disease that at least partially involves genetic and environmental perturbations to gene-networks connecting the hypothalamus and several metabolic tissues, resulting in an energy imbalance at the systems level. To provide an inter-tissue view of obesity with respec...

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Bibliographic Details

Published in:	Genome biology Vol. 10; no. 5; p. R55
Main Authors:	Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, Allan, Mark F, Pomp, Daniel, Schadt, Eric E
Format:	Journal Article
Language:	English
Published:	England BioMed Central 22-05-2009
Subjects:	Adipose Tissue - metabolism Animals Gene Regulatory Networks Humans Liver - metabolism Mice Obesity - genetics Obesity - physiopathology
Online Access:	Get full text
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