Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse

A number of calcium buffers were examined for their ability to reduce evoked transmitter release when injected into the presynaptic terminal of the squid giant synapse. Injection of EGTA was virtually ineffective at reducing transmitter release, even at estimated intracellular concentrations up to 8...

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Bibliographic Details
Published in:	The Journal of neuroscience Vol. 11; no. 6; pp. 1496 - 1507
Main Authors:	Adler, EM, Augustine, GJ, Duffy, SN, Charlton, MP
Format:	Journal Article
Language:	English
Published:	Washington, DC Soc Neuroscience 01-06-1991 Society for Neuroscience
Subjects:	Animals Biochemistry. Physiology. Immunology Biological and medical sciences Buffers Calcium - physiology Chelating Agents - pharmacology Decapodiformes Edetic Acid - pharmacology Egtazic Acid - pharmacology Fundamental and applied biological sciences. Psychology Invertebrates Iontophoresis Kinetics Loligo Mollusca Neurotransmitter Agents - secretion Physiology. Development Synapses - drug effects Synapses - physiology Calcium Electrophysiology Loligo pealei Nervous system Cephalopoda Nervous ganglion Synapse Stellate ganglion Neuromediator Giant neuron Chelating agent Loligo opalescens Membrane potential Presynaptic nerve ending Invertebrata Mollusca Release
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