Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect

Vascular endothelial growth factors (VEGFs) and their receptors are essential regulators of vasculogenesis and angiogenesis in both embryos and adults. One of the factors with a still unknown physiological function is VEGF-B, which is expressed in many tissues, including the heart. Mice carrying a t...

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Bibliographic Details
Published in:	Circulation (New York, N.Y.) Vol. 104; no. 3; pp. 358 - 364
Main Authors:	AASE, Karin, VON EULER, Gabriel, ALITALO, Kari, BETSHOLTZ, Christer, ERIKSSON, Ulf, XURI LI, PONTEN, Annica, THOREN, Peter, RENHAI CAO, YIHAI CAO, OLOFSSON, Birgitta, GEBRE-MEDHIN, Samuel, PEKNY, Milos
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Lippincott Williams & Wilkins 17-07-2001 American Heart Association, Inc
Subjects:	Animals Biological and medical sciences Blood Cell Count Electrocardiography Electrophysiologic Techniques, Cardiac Endothelial Growth Factors - deficiency Endothelial Growth Factors - genetics Endothelial Growth Factors - metabolism Endothelial Growth Factors - pharmacology Eye - blood supply Eye - drug effects Female Fertility - genetics Fetal Viability - genetics Fibroblast Growth Factor 2 - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression - physiology Gene Targeting Heart Heart Atria - growth & development Heart Atria - physiopathology Heart Conduction System - physiopathology Homozygote Lymphokines - pharmacology Male Medicin och hälsovetenskap Mice Mice, Knockout Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - physiology Organ Size Phenotype RNA, Messenger - metabolism Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor B Vascular Endothelial Growth Factors Vertebrates: cardiovascular system Heart Angiogenesis Conduction Atrium Vertebrata Mammalia Vascular endothelium growth factor Mouse Animal Rodentia Physiology Circulatory system
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