NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals

Crm1-dependent Nuclear Export Signals (NESs) are clusters of alternating hydrophobic and non-hydrophobic amino acid residues between 10 to 15 amino acids in length. NESs were largely thought to follow simple consensus patterns, based on which they were categorized into 6-10 classes. However, newly d...

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Bibliographic Details
Published in:	BMC bioinformatics Vol. 19; no. 1; p. 65
Main Authors:	Liku, Muluye E, Legere, Elizabeth-Ann, Moses, Alan M
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 27-02-2018 BioMed Central BMC
Subjects:	Algorithms Amino Acid Sequence Amino acids Analysis Cluster Analysis Crm1 Export Exportin 1 Protein Humans Hydrophobic and Hydrophilic Interactions Karyopherins - chemistry Karyopherins - metabolism Markov Chains Methodology Models, Statistical Nuclear Export Signals Position-Specific Scoring Matrices Probability Receptors, Cytoplasmic and Nuclear - chemistry Receptors, Cytoplasmic and Nuclear - metabolism Saccharomyces cerevisiae - metabolism Software Statistical models Variable length motif model Export Variable length motif model Algorithms Crm1 Nuclear export signals
Online Access:	Get full text
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