Increased prime edit rates in KCNQ2 and SCN1A via single nicking all-in-one plasmids

Prime editing (PE) is the most recent gene editing technology able to introduce targeted alterations to the genome, including single base pair changes, small insertions, and deletions. Several improvements to the PE machinery have been made in the past few years, and these have been tested in a rang...

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Bibliographic Details
Published in:BMC biology Vol. 21; no. 1; p. 156
Main Authors: Dirkx, N, Weuring, Wout J, De Vriendt, E, Smal, N, van de Vondervoort, J, van 't Slot, Ruben, Koetsier, M, Zonnekein, N, De Pooter, Tim, Weckhuysen, S, Koeleman, B P C
Format: Journal Article
Language:English
Published: England BioMed Central Ltd 13-07-2023
BioMed Central
BMC
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