Meiotic sex in Chagas disease parasite Trypanosoma cruzi

Meiotic sex in Chagas disease parasite Trypanosoma cruzi

Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi , the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to exchange genetic material rarely and without c...

Full description

Saved in:
Bibliographic Details
Published in:Nature communications Vol. 10; no. 1; pp. 3972 - 14
Main Authors: Schwabl, Philipp, Imamura, Hideo, Van den Broeck, Frederik, Costales, Jaime A., Maiguashca-Sánchez, Jalil, Miles, Michael A., Andersson, Bjorn, Grijalva, Mario J., Llewellyn, Martin S.
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 03-09-2019
Nature Publishing Group
Nature Portfolio
Subjects:
45/23
631/158/1469
631/181/2474
631/181/457
631/326/417/2551
Animals
Chagas disease
Chagas Disease - parasitology
Chiroptera - parasitology
Ecuador
Epidemiology
Exchanging
Genetic engineering
Genetic Variation
Genetics, Population
Genome, Protozoan
Genomes
Humanities and Social Sciences
Hybridization
Life cycles
Medicin och hälsovetenskap
Meiosis
multidisciplinary
Parasites
Parasitic diseases
Phenotypes
Protozoa
Public health
Recombination, Genetic
Reproduction - genetics
Rodentia - parasitology
Science
Science (multidisciplinary)
Sequence Analysis, DNA
Sex
Triatominae - parasitology
Trypanosoma cruzi
Trypanosoma cruzi - genetics
Vector-borne diseases
Vectors
Virulence
Ecuador
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi , the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to exchange genetic material rarely and without classic meiotic sex. We present compelling evidence from 45 genomes sequenced from southern Ecuador that T. cruzi in fact maintains truly sexual, panmictic groups that can occur alongside others that remain highly clonal after past hybridization events. These groups with divergent reproductive strategies appear genetically isolated despite possible co-occurrence in vectors and hosts. We propose biological explanations for the fine-scale disconnectivity we observe and discuss the epidemiological consequences of flexible reproductive modes. Our study reinvigorates the hunt for the site of genetic exchange in the T. cruzi life cycle, provides tools to define the genetic determinants of parasite virulence, and reforms longstanding theory on clonality in trypanosomatid parasites. Here, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi , the causative agent of Chagas disease. These findings have implications for the epidemiology of the disease in endemic regions and challenge existing ideas that the parasites are strictly clonal.
AbstractList Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi, the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to exchange genetic material rarely and without classic meiotic sex. We present compelling evidence from 45 genomes sequenced from southern Ecuador that T. cruzi in fact maintains truly sexual, panmictic groups that can occur alongside others that remain highly clonal after past hybridization events. These groups with divergent reproductive strategies appear genetically isolated despite possible co-occurrence in vectors and hosts. We propose biological explanations for the fine-scale disconnectivity we observe and discuss the epidemiological consequences of flexible reproductive modes. Our study reinvigorates the hunt for the site of genetic exchange in the T. cruzi life cycle, provides tools to define the genetic determinants of parasite virulence, and reforms longstanding theory on clonality in trypanosomatid parasites.
Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi , the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to exchange genetic material rarely and without classic meiotic sex. We present compelling evidence from 45 genomes sequenced from southern Ecuador that T. cruzi in fact maintains truly sexual, panmictic groups that can occur alongside others that remain highly clonal after past hybridization events. These groups with divergent reproductive strategies appear genetically isolated despite possible co-occurrence in vectors and hosts. We propose biological explanations for the fine-scale disconnectivity we observe and discuss the epidemiological consequences of flexible reproductive modes. Our study reinvigorates the hunt for the site of genetic exchange in the T. cruzi life cycle, provides tools to define the genetic determinants of parasite virulence, and reforms longstanding theory on clonality in trypanosomatid parasites.
Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi , the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to exchange genetic material rarely and without classic meiotic sex. We present compelling evidence from 45 genomes sequenced from southern Ecuador that T. cruzi in fact maintains truly sexual, panmictic groups that can occur alongside others that remain highly clonal after past hybridization events. These groups with divergent reproductive strategies appear genetically isolated despite possible co-occurrence in vectors and hosts. We propose biological explanations for the fine-scale disconnectivity we observe and discuss the epidemiological consequences of flexible reproductive modes. Our study reinvigorates the hunt for the site of genetic exchange in the T. cruzi life cycle, provides tools to define the genetic determinants of parasite virulence, and reforms longstanding theory on clonality in trypanosomatid parasites. Here, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi , the causative agent of Chagas disease. These findings have implications for the epidemiology of the disease in endemic regions and challenge existing ideas that the parasites are strictly clonal.
Here, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi, the causative agent of Chagas disease. These findings have implications for the epidemiology of the disease in endemic regions and challenge existing ideas that the parasites are strictly clonal.
ArticleNumber 3972
Author Schwabl, Philipp
Andersson, Bjorn
Maiguashca-Sánchez, Jalil
Van den Broeck, Frederik
Costales, Jaime A.
Miles, Michael A.
Imamura, Hideo
Grijalva, Mario J.
Llewellyn, Martin S.
Author_xml – sequence: 1
  givenname: Philipp
  orcidid: 0000-0002-1244-945X
  surname: Schwabl
  fullname: Schwabl, Philipp
  organization: Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow
– sequence: 2
  givenname: Hideo
  orcidid: 0000-0002-3282-1319
  surname: Imamura
  fullname: Imamura, Hideo
  organization: Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp
– sequence: 3
  givenname: Frederik
  orcidid: 0000-0003-2542-5585
  surname: Van den Broeck
  fullname: Van den Broeck, Frederik
  organization: Unit of Molecular Parasitology, Institute of Tropical Medicine Antwerp
– sequence: 4
  givenname: Jaime A.
  orcidid: 0000-0001-9418-6640
  surname: Costales
  fullname: Costales, Jaime A.
  organization: Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador
– sequence: 5
  givenname: Jalil
  orcidid: 0000-0001-8513-4064
  surname: Maiguashca-Sánchez
  fullname: Maiguashca-Sánchez, Jalil
  organization: Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador
– sequence: 6
  givenname: Michael A.
  surname: Miles
  fullname: Miles, Michael A.
  organization: London School of Hygiene & Tropical Medicine
– sequence: 7
  givenname: Bjorn
  orcidid: 0000-0002-4624-0259
  surname: Andersson
  fullname: Andersson, Bjorn
  organization: Department of Cell and Molecular Biology, Science for Life Laboratory, Karolinska Institutet
– sequence: 8
  givenname: Mario J.
  orcidid: 0000-0003-1964-1425
  surname: Grijalva
  fullname: Grijalva, Mario J.
  organization: Center for Research on Health in Latin America, School of Biological Sciences, Pontifical Catholic University of Ecuador, Infectious and Tropical Disease Institute, Biomedical Sciences Department, Heritage College of Osteopathic Medicine, Ohio University
– sequence: 9
  givenname: Martin S.
  orcidid: 0000-0001-9856-1591
  surname: Llewellyn
  fullname: Llewellyn, Martin S.
  email: martin.llewellyn@glasgow.ac.uk
  organization: Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31481692$$D View this record in MEDLINE/PubMed
http://kipublications.ki.se/Default.aspx?queryparsed=id:141790549$$DView record from Swedish Publication Index
BookMark eNp9kk1vEzEQhi1UREvoH-CAVuLCZcFje_1xQUIRlEpFXMrZ8npnU4fNerEToPn1dZpQGg5YsmzNvPPYHr_PyckYRyTkJdC3QLl-lwUIqWoKpgZQCurtE3LGqIAaFOMnj_an5DznJS2DG9BCPCOnHIQGadgZ0V8wxHXwVcbfVRir-Y1buFx1IaPLWE0uuRzWWF2n28mNMceVq3zabMML8rR3Q8bzwzoj3z59vJ5_rq--XlzOP1zVXjK9rgVS6TvXKip0i0ZrCbLvleS8NY1DoRC80ayhRmo0vsNeo3QtF1yJXtCGz8jlnttFt7RTCiuXbm10wd4HYlpYl8oDBrSi5bRx3uueSmEYtFIyrh2XXoLivS4ss2flXzht2iPalGJnD_HvYTdtRgsClKGNMKX2_b62CFbYeRzXyQ3HiKPMGG7sIv60UjEGghfAmwMgxR8bzGu7CtnjMLgR4yZbxrRoGiaELNLX_0iXcZPG0uadipvG7D5zRthe5VPMOWH_cBmgducRu_eILR6x9x6x21L06vEzHkr-OKII-KFHJTUuMP09-z_YOz9cyLU
CitedBy_id crossref_primary_10_3390_life13122339
crossref_primary_10_1371_journal_pntd_0007770
crossref_primary_10_1590_1678_4685_gmb_2022_0065
crossref_primary_10_3390_biology10060471
crossref_primary_10_1007_s00436_023_07850_2
crossref_primary_10_1038_s42003_021_01658_5
crossref_primary_10_1080_21505594_2020_1797274
crossref_primary_10_1590_0074_02760210193chgsa
crossref_primary_10_3389_fcimb_2023_1147998
crossref_primary_10_1021_acsinfecdis_2c00123
crossref_primary_10_1016_j_pt_2020_01_007
crossref_primary_10_1016_j_pt_2020_01_008
crossref_primary_10_3389_fcimb_2021_614665
crossref_primary_10_1016_j_meegid_2022_105251
crossref_primary_10_1590_0074_02760200634
crossref_primary_10_1017_S0031182023000070
crossref_primary_10_1371_journal_pntd_0007910
crossref_primary_10_1038_s41598_021_91783_2
crossref_primary_10_1590_0074_02760220164
crossref_primary_10_3390_tropicalmed5030129
crossref_primary_10_3390_pathogens10020212
crossref_primary_10_1099_mgen_0_000843
crossref_primary_10_1371_journal_pntd_0009269
crossref_primary_10_3390_genes11091085
crossref_primary_10_1371_journal_pntd_0010110
crossref_primary_10_1371_journal_pntd_0009141
crossref_primary_10_3389_fcimb_2022_760830
crossref_primary_10_7554_eLife_75237
crossref_primary_10_1371_journal_pgen_1009170
crossref_primary_10_1139_gen_2020_0092
crossref_primary_10_3389_fcimb_2020_582192
crossref_primary_10_1038_s42003_021_01762_6
crossref_primary_10_3389_fcimb_2020_00010
crossref_primary_10_3390_genes11101196
crossref_primary_10_1016_j_meegid_2022_105344
crossref_primary_10_3390_microorganisms9112409
crossref_primary_10_3390_pathogens9050356
crossref_primary_10_3390_microorganisms12050855
crossref_primary_10_1111_mec_15582
crossref_primary_10_3389_fcimb_2021_672448
crossref_primary_10_1186_s12859_021_04384_1
crossref_primary_10_7717_peerj_8947
crossref_primary_10_3389_fcell_2021_669041
crossref_primary_10_3390_pathogens10111493
Cites_doi 10.1016/j.molbiopara.2005.04.009
10.1371/journal.pntd.0001363
10.1093/molbev/msj030
10.1111/j.1462-5822.2010.01534.x
10.1046/j.1365-294X.2003.01998.x
10.1016/j.ijpara.2006.06.019
10.1016/0166-6851(91)90029-6
10.1016/j.cub.2013.11.044
10.7554/eLife.12613
10.1016/0092-8674(90)90674-4
10.1073/pnas.0707314105
10.1038/nature01438
10.1093/bioinformatics/btr330
10.1016/j.actatropica.2015.05.007
10.1016/0092-8674(86)90063-2
10.1111/j.1365-2656.2010.01726.x
10.4269/ajtmh.2007.76.573
10.1101/cshperspect.a019604
10.1111/mec.12872
10.4161/fly.19695
10.1371/journal.pgen.1003905
10.1016/j.molbiopara.2008.04.009
10.1111/mec.14809
10.1016/j.actatropica.2015.05.029
10.1016/j.mib.2015.06.017
10.1073/pnas.121187198
10.1126/science.1061888
10.1371/journal.pone.0030377
10.1371/journal.pgen.1002453
10.1016/j.ijpara.2006.08.002
10.1086/521987
10.1371/journal.pntd.0004142
10.1073/pnas.87.7.2414
10.1038/287536a0
10.1038/ng.806
10.1371/journal.pgen.1008042
10.1186/1471-2164-12-139
10.1371/journal.pgen.1004092
10.1128/mBio.01399-18
10.1371/journal.pgen.1003672
10.1038/nmeth.3407
10.1093/bioinformatics/16.10.944
10.1126/science.1092500
10.1371/journal.pntd.0007392
10.1371/journal.pntd.0002960
10.1016/B978-0-12-385863-4.00002-2
10.1186/1756-3305-1-4
10.1111/j.1558-5646.1986.tb00573.x
10.1073/pnas.0904420106
10.1186/s13071-017-2406-z
10.1186/1756-3305-7-78
10.1093/emboj/cdg235
10.1016/S0140-6736(17)31612-4
10.1371/journal.pntd.0000961
10.1371/journal.pgen.0030186
10.1534/genetics.116.194720
10.1186/1471-2156-11-94
10.7554/eLife.11473
10.1534/genetics.115.178004
10.1016/j.ijpara.2009.04.001
10.1016/j.pt.2006.02.006
10.1126/science.1169464
10.1016/j.cub.2017.07.007
10.1016/j.ijpara.2007.02.002
10.1111/mec.14271
10.1016/S0959-437X(98)80142-1
10.1126/science.288.5469.1211
10.1111/j.1471-8286.2004.00828.x
10.1007/978-1-4939-1438-8_19
10.1038/nature09221
10.1101/283531
10.1111/j.1095-8312.2004.00325.x
10.1016/B978-0-12-801029-7.00021-6
10.1093/genetics/136.1.343
10.1099/mgen.0.000223
10.1093/genetics/159.2.893
ContentType Journal Article
Copyright The Author(s) 2019
2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2019
– notice: 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
3V.
7QL
7QP
7QR
7SN
7SS
7ST
7T5
7T7
7TM
7TO
7X7
7XB
88E
8AO
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABUWG
AFKRA
ARAPS
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
C1K
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
LK8
M0S
M1P
M7P
P5Z
P62
P64
PIMPY
PQEST
PQQKQ
PQUKI
PRINS
RC3
SOI
7X8
5PM
ADTPV
AOWAS
D8T
ZZAVC
DOA
DOI 10.1038/s41467-019-11771-z
DatabaseName SpringerOpen
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
Calcium & Calcified Tissue Abstracts
Chemoreception Abstracts
Ecology Abstracts
Entomology Abstracts (Full archive)
Environment Abstracts
Immunology Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
Nucleic Acids Abstracts
Oncogenes and Growth Factors Abstracts
ProQuest_Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
Advanced Technologies & Aerospace Database‎ (1962 - current)
ProQuest Central Essentials
Biological Science Collection
AUTh Library subscriptions: ProQuest Central
Technology Collection
ProQuest Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection (Proquest) (PQ_SDU_P3)
ProQuest Health & Medical Complete (Alumni)
Biological Sciences
Health & Medical Collection (Alumni Edition)
PML(ProQuest Medical Library)
Biological Science Database
ProQuest Advanced Technologies & Aerospace Database
ProQuest Advanced Technologies & Aerospace Collection
Biotechnology and BioEngineering Abstracts
Publicly Available Content Database (Proquest) (PQ_SDU_P3)
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
Genetics Abstracts
Environment Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
SwePub
SwePub Articles
SWEPUB Freely available online
SwePub Articles full text
Directory of Open Access Journals
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Publicly Available Content Database
ProQuest Central Student
Oncogenes and Growth Factors Abstracts
ProQuest Advanced Technologies & Aerospace Collection
ProQuest Central Essentials
Nucleic Acids Abstracts
SciTech Premium Collection
ProQuest Central China
Environmental Sciences and Pollution Management
Health Research Premium Collection
Natural Science Collection
Biological Science Collection
Chemoreception Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
ProQuest Medical Library (Alumni)
Advanced Technologies & Aerospace Collection
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
Ecology Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Entomology Abstracts
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Engineering Research Database
ProQuest One Academic
Calcium & Calcified Tissue Abstracts
Technology Collection
Technology Research Database
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central
Genetics Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
AIDS and Cancer Research Abstracts
ProQuest SciTech Collection
Advanced Technologies & Aerospace Database
ProQuest Medical Library
Immunology Abstracts
Environment Abstracts
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE
CrossRef



Publicly Available Content Database
Database_xml – sequence: 1
  dbid: DOA
  name: Directory of Open Access Journals
  url: http://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: ECM
  name: MEDLINE
  url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
Public Health
EISSN 2041-1723
EndPage 14
ExternalDocumentID oai_doaj_org_article_4b305acc8f064921b66238a36c6173f8
oai_prod_swepub_kib_ki_se_141790549
10_1038_s41467_019_11771_z
31481692
Genre Research Support, Non-U.S. Gov't
Journal Article
Research Support, N.I.H., Extramural
GeographicLocations Ecuador
GeographicLocations_xml – name: Ecuador
GrantInformation_xml – fundername: Scottish Funding Council (SFC)
  funderid: https://doi.org/10.13039/501100000360
– fundername: U.S. Department of Health & Human Services | NIH | Fogarty International Center (FIC)
  grantid: TW008261
  funderid: https://doi.org/10.13039/100000061
– fundername: Pontificia Universidad Católica del Ecuador (Pontifical Catholic University of Ecuador)
  grantid: I13048, J13033, K13063 and L13225
  funderid: https://doi.org/10.13039/501100011749
– fundername: U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
  grantid: AI077896-01; AI105749-01A1
  funderid: https://doi.org/10.13039/100000060
– fundername: Medical Research Council
  grantid: MR/M026353/1
– fundername: Wellcome Trust
  grantid: 204820/Z/16/Z
– fundername: ;
– fundername: ;
  grantid: AI077896-01; AI105749-01A1
– fundername: ;
  grantid: TW008261
– fundername: ;
  grantid: I13048, J13033, K13063 and L13225
GroupedDBID ---
0R~
39C
3V.
53G
5VS
70F
7X7
88E
8AO
8FE
8FG
8FH
8FI
8FJ
AAHBH
AAJSJ
ABUWG
ACGFO
ACGFS
ACIWK
ACMJI
ACPRK
ACSMW
ADBBV
ADFRT
ADRAZ
AENEX
AFKRA
AFRAH
AHMBA
AJTQC
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AMTXH
AOIJS
ARAPS
ASPBG
AVWKF
AZFZN
BBNVY
BCNDV
BENPR
BGLVJ
BHPHI
BPHCQ
BVXVI
C6C
CCPQU
DIK
EBLON
EBS
EE.
EMOBN
F5P
FEDTE
FYUFA
GROUPED_DOAJ
HCIFZ
HMCUK
HVGLF
HYE
HZ~
KQ8
LK8
M1P
M48
M7P
M~E
NAO
O9-
OK1
P2P
P62
PIMPY
PQQKQ
PROAC
PSQYO
RNS
RNT
RNTTT
RPM
SNYQT
SV3
TSG
UKHRP
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7QL
7QP
7QR
7SN
7SS
7ST
7T5
7T7
7TM
7TO
7XB
8FD
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
H94
K9.
P64
PQEST
PQUKI
PRINS
RC3
SOI
7X8
5PM
4.4
ABAWZ
ADTPV
AOWAS
BAPOH
CAG
COF
D8T
EJD
LGEZI
LOTEE
NADUK
NXXTH
ZZAVC
ID FETCH-LOGICAL-c628t-4e06cdab7048be988616ff7633b95ae47e1c98250968e9cdef8e6ab34374f4053
IEDL.DBID RPM
ISSN 2041-1723
IngestDate Tue Oct 22 15:12:29 EDT 2024
Wed Oct 30 05:05:06 EDT 2024
Tue Sep 17 21:11:57 EDT 2024
Tue Aug 27 04:38:30 EDT 2024
Tue Nov 05 14:57:28 EST 2024
Thu Nov 21 21:01:53 EST 2024
Sat Sep 28 08:45:58 EDT 2024
Fri Oct 11 20:46:46 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
License Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c628t-4e06cdab7048be988616ff7633b95ae47e1c98250968e9cdef8e6ab34374f4053
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0002-3282-1319
0000-0002-4624-0259
0000-0003-1964-1425
0000-0002-1244-945X
0000-0001-9856-1591
0000-0003-2542-5585
0000-0001-9418-6640
0000-0001-8513-4064
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722143/
PMID 31481692
PQID 2283959000
PQPubID 546298
PageCount 14
ParticipantIDs doaj_primary_oai_doaj_org_article_4b305acc8f064921b66238a36c6173f8
swepub_primary_oai_prod_swepub_kib_ki_se_141790549
pubmedcentral_primary_oai_pubmedcentral_nih_gov_6722143
proquest_miscellaneous_2284552446
proquest_journals_2283959000
crossref_primary_10_1038_s41467_019_11771_z
pubmed_primary_31481692
springer_journals_10_1038_s41467_019_11771_z
PublicationCentury 2000
PublicationDate 2019-09-03
PublicationDateYYYYMMDD 2019-09-03
PublicationDate_xml – month: 09
  year: 2019
  text: 2019-09-03
  day: 03
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle Nature communications
PublicationTitleAbbrev Nat Commun
PublicationTitleAlternate Nat Commun
PublicationYear 2019
Publisher Nature Publishing Group UK
Nature Publishing Group
Nature Portfolio
Publisher_xml – name: Nature Publishing Group UK
– name: Nature Publishing Group
– name: Nature Portfolio
References Ramírez, Llewellyn (CR8) 2014; 23
Balmer, Beadell, Gibson, Caccone (CR57) 2011; 5
Ramesh, Malik, Logsdon (CR7) 2005; 15
Tihon, Imamura, Dujardin, Abbeele, Van den Broeck (CR12) 2017; 26
Browning, Browning (CR67) 2007; 81
Volf (CR61) 2007; 37
CR37
Inbar (CR50) 2013; 9
CR79
Weir (CR14) 2016; 5
Smith, Nicolas (CR34) 1998; 8
Van den Broeck, Tavernier, Vermeiren, Dujardin, Van den Abbeele (CR13) 2018; 27
Danecek (CR72) 2011; 27
Pérez-Molina, Molina (CR1) 2018; 391
Paradis, Claude, Strimmer (CR70) 2004
Inbar (CR18) 2019; 15
Peacock, Ferris, Bailey, Gibson (CR55) 2008; 160
Peacock, Ferris, Bailey, Gibson (CR56) 2014; 7
Lawson, Hellenthal, Myers, Falush (CR28) 2012; 8
Machado, Ayala (CR58) 2001; 98
Jombart, Devillard, Balloux (CR69) 2010; 11
CR3
Agabian (CR6) 1990; 61
Tait (CR9) 1980; 287
Nolder, Roncal, Davies, Llanos-Cuentas, Miles (CR16) 2007; 76
Lin, Litvintseva, Nielsen, Patel, Floyd, Mitchell, Heitman (CR49) 2007; 3
Rutherford (CR78) 2000; 16
Ravel (CR15) 2006; 36
Gibson, Garside (CR48) 1991; 45
Berry (CR21) 2019; 13
Hartfield, Wright, Agrawal (CR53) 2016; 202
CR44
DePristo (CR64) 2011; 43
Rogers (CR75) 2014; 10
Wakeley, Aliacar (CR51) 2001; 159
Gaunt (CR22) 2003; 421
Rougeron (CR19) 2009; 106
González-Martínez, Ridout, Pannell (CR52) 2017; 27
Vorburger, Lancaster, Sunnucks (CR45) 2003; 12
Peacock, Bailey, Carrington, Gibson (CR11) 2014; 24
Tibayrenc, Kjellberg, Ayala (CR26) 1990; 87
Imamura (CR39) 2016; 5
Minning, Weatherly, Flibotte, Tarleton (CR24) 2011; 12
Bennett (CR33) 2015; 28
Martin, Van Belleghem (CR29) 2017; 206
Messenger, Miles (CR20) 2015; 151
Lehto, Haag (CR46) 2010; 79
Schenck, Vrijenhoek (CR43) 1986; 40
Akopyants (CR17) 2009; 324
Excoffier, Smouse (CR80) 1994; 136
MacLeod (CR10) 2005; 143
Benne (CR5) 1986; 46
Lewis (CR59) 2011; 5
Bern, Martin, Gilman (CR2) 2011; 75
Bennett, Johnson (CR31) 2003; 22
Excoffier, Dupanloup, Huerta-Sánchez, Sousa, Foll (CR77) 2013; 9
Tsai, Bensasson, Burt, Koufopanou (CR73) 2008; 105
Gibson, Peacock, Ferris, Williams, Bailey (CR54) 2008; 1
Simpson, Stevens, Lukeš (CR4) 2006; 22
Sterkers, Lachaud, Crobu, Bastien, Pagès (CR35) 2011; 13
McVean (CR74) 2004; 304
Bussotti (CR38) 2018; 9
Mark Welch, Meselson (CR30) 2000; 288
Cingolani (CR66) 2012; 6
Lewis (CR23) 2009; 39
CR27
Zeledón, Alvarado, Jirón (CR40) 1977; 34
Ewing (CR76) 2015; 12
CR25
Haag, Ebert (CR47) 2004; 41
Tihon, Imamura, Dujardin (CR36) 2017; 10
Gürtler, Cardinal (CR41) 2015; 151
Huson, Bryant (CR68) 2006; 23
Bennett, Forche, Berman (CR32) 2014; 4
Grijalva, Terán (CR42) 2014; 8
Grigg, Bonnefoy, Hehl, Suzuki, Boothroyd (CR60) 2001; 294
Grijalva (CR62) 2015; 9
Derrien, Estellé, Marco Sola, Knowles, Raineri, Guigó, Ribeca (CR65) 2012; 7
Yeo (CR63) 2007; 37
Goudet (CR71) 2005; 5
RE Gürtler (11771_CR41) 2015; 151
GAT McVean (11771_CR74) 2004; 304
RJ Bennett (11771_CR31) 2003; 22
KN Smith (11771_CR34) 1998; 8
11771_CR44
MA Ramesh (11771_CR7) 2005; 15
W Weir (11771_CR14) 2016; 5
M Yeo (11771_CR63) 2007; 37
MD Lewis (11771_CR23) 2009; 39
L Excoffier (11771_CR80) 1994; 136
LA Messenger (11771_CR20) 2015; 151
JA Pérez-Molina (11771_CR1) 2018; 391
11771_CR37
SC González-Martínez (11771_CR52) 2017; 27
R Benne (11771_CR5) 1986; 46
ASF Berry (11771_CR21) 2019; 13
MW Gaunt (11771_CR22) 2003; 421
L Peacock (11771_CR55) 2008; 160
A Tait (11771_CR9) 1980; 287
V Rougeron (11771_CR19) 2009; 106
RA Schenck (11771_CR43) 1986; 40
M Hartfield (11771_CR53) 2016; 202
CR Haag (11771_CR47) 2004; 41
AGB Simpson (11771_CR4) 2006; 22
W Gibson (11771_CR54) 2008; 1
J Goudet (11771_CR71) 2005; 5
R Zeledón (11771_CR40) 1977; 34
E Inbar (11771_CR50) 2013; 9
C Vorburger (11771_CR45) 2003; 12
11771_CR79
MJ Grijalva (11771_CR62) 2015; 9
K Rutherford (11771_CR78) 2000; 16
H Imamura (11771_CR39) 2016; 5
M Tibayrenc (11771_CR26) 1990; 87
RJ Bennett (11771_CR33) 2015; 28
G Bussotti (11771_CR38) 2018; 9
SR Browning (11771_CR67) 2007; 81
E Inbar (11771_CR18) 2019; 15
Y Sterkers (11771_CR35) 2011; 13
DH Huson (11771_CR68) 2006; 23
P Cingolani (11771_CR66) 2012; 6
P Danecek (11771_CR72) 2011; 27
11771_CR27
11771_CR25
NS Akopyants (11771_CR17) 2009; 324
Xiaorong Lin (11771_CR49) 2007; 3
AD Ewing (11771_CR76) 2015; 12
T Jombart (11771_CR69) 2010; 11
MJ Grijalva (11771_CR42) 2014; 8
W Gibson (11771_CR48) 1991; 45
L Excoffier (11771_CR77) 2013; 9
TA Minning (11771_CR24) 2011; 12
J Wakeley (11771_CR51) 2001; 159
SH Martin (11771_CR29) 2017; 206
D Mark Welch (11771_CR30) 2000; 288
P Volf (11771_CR61) 2007; 37
A MacLeod (11771_CR10) 2005; 143
D Nolder (11771_CR16) 2007; 76
E Paradis (11771_CR70) 2004
MD Lewis (11771_CR59) 2011; 5
C Bern (11771_CR2) 2011; 75
RJ Bennett (11771_CR32) 2014; 4
F Van den Broeck (11771_CR13) 2018; 27
C Ravel (11771_CR15) 2006; 36
MB Rogers (11771_CR75) 2014; 10
E Tihon (11771_CR12) 2017; 26
IJ Tsai (11771_CR73) 2008; 105
DJ Lawson (11771_CR28) 2012; 8
O Balmer (11771_CR57) 2011; 5
CA Machado (11771_CR58) 2001; 98
Thomas Derrien (11771_CR65) 2012; 7
N Agabian (11771_CR6) 1990; 61
L Peacock (11771_CR11) 2014; 24
11771_CR3
MP Lehto (11771_CR46) 2010; 79
JD Ramírez (11771_CR8) 2014; 23
ME Grigg (11771_CR60) 2001; 294
MA DePristo (11771_CR64) 2011; 43
E Tihon (11771_CR36) 2017; 10
L Peacock (11771_CR56) 2014; 7
References_xml – volume: 15
  start-page: 185
  year: 2005
  end-page: 191
  ident: CR7
  article-title: A phylogenomic inventory of meiotic genes: evidence for sex in and an early eukaryotic origin of meiosis
  publication-title: Curr. Biol.
  contributor:
    fullname: Logsdon
– volume: 143
  start-page: 12
  year: 2005
  end-page: 19
  ident: CR10
  article-title: Allelic segregation and independent assortment in crosses: proof that the genetic system is Mendelian and involves meiosis
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/j.molbiopara.2005.04.009
  contributor:
    fullname: MacLeod
– volume: 5
  start-page: e1363
  year: 2011
  ident: CR59
  article-title: Recent, Independent and anthropogenic origins of hybrids
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0001363
  contributor:
    fullname: Lewis
– volume: 23
  start-page: 254
  year: 2006
  end-page: 267
  ident: CR68
  article-title: Application of phylogenetic networks in evolutionary studies
  publication-title: Mol. Biol. Evol.
  doi: 10.1093/molbev/msj030
  contributor:
    fullname: Bryant
– volume: 13
  start-page: 274
  year: 2011
  end-page: 283
  ident: CR35
  article-title: FISH analysis reveals aneuploidy and continual generation of chromosomal mosaicism in
  publication-title: Cell. Microbiol
  doi: 10.1111/j.1462-5822.2010.01534.x
  contributor:
    fullname: Pagès
– volume: 12
  start-page: 3493
  year: 2003
  end-page: 3504
  ident: CR45
  article-title: Environmentally related patterns of reproductive modes in the aphid and the predominance of two ‘superclones’ in Victoria, Australia
  publication-title: Mol. Ecol.
  doi: 10.1046/j.1365-294X.2003.01998.x
  contributor:
    fullname: Sunnucks
– volume: 36
  start-page: 1383
  year: 2006
  end-page: 1388
  ident: CR15
  article-title: First report of genetic hybrids between two very divergent species: and
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2006.06.019
  contributor:
    fullname: Ravel
– volume: 45
  start-page: 77
  year: 1991
  end-page: 89
  ident: CR48
  article-title: Genetic exchange in : variable chromosomal location of housekeeping genes in different trypanosome stocks
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/0166-6851(91)90029-6
  contributor:
    fullname: Garside
– volume: 24
  start-page: 181
  year: 2014
  end-page: 186
  ident: CR11
  article-title: Meiosis and haploid gametes in the pathogen
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2013.11.044
  contributor:
    fullname: Gibson
– volume: 5
  start-page: e12613
  year: 2016
  ident: CR39
  article-title: Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
  publication-title: eLife
  doi: 10.7554/eLife.12613
  contributor:
    fullname: Imamura
– volume: 61
  start-page: 1157
  year: 1990
  end-page: 1160
  ident: CR6
  article-title: Trans splicing of nuclear pre-mRNAs
  publication-title: Cell
  doi: 10.1016/0092-8674(90)90674-4
  contributor:
    fullname: Agabian
– volume: 105
  start-page: 4957
  year: 2008
  end-page: 4962
  ident: CR73
  article-title: Population genomics of the wild yeast : Quantifying the life cycle
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.0707314105
  contributor:
    fullname: Koufopanou
– volume: 421
  start-page: 936
  year: 2003
  end-page: 939
  ident: CR22
  article-title: Mechanism of genetic exchange in American trypanosomes
  publication-title: Nature
  doi: 10.1038/nature01438
  contributor:
    fullname: Gaunt
– volume: 27
  start-page: 2156
  year: 2011
  end-page: 2158
  ident: CR72
  article-title: The variant call format and VCFtools
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btr330
  contributor:
    fullname: Danecek
– volume: 151
  start-page: 150
  year: 2015
  end-page: 155
  ident: CR20
  article-title: Evidence and importance of genetic exchange among field populations of
  publication-title: Acta Trop.
  doi: 10.1016/j.actatropica.2015.05.007
  contributor:
    fullname: Miles
– volume: 46
  start-page: 819
  year: 1986
  end-page: 826
  ident: CR5
  article-title: Major transcript of the frameshifted gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA
  publication-title: Cell
  doi: 10.1016/0092-8674(86)90063-2
  contributor:
    fullname: Benne
– volume: 79
  start-page: 1241
  year: 2010
  end-page: 1250
  ident: CR46
  article-title: Ecological differentiation between coexisting sexual and asexual strains of
  publication-title: J. Anim. Ecol.
  doi: 10.1111/j.1365-2656.2010.01726.x
  contributor:
    fullname: Haag
– volume: 76
  start-page: 573
  year: 2007
  end-page: 578
  ident: CR16
  article-title: Multiple hybrid genotypes of ( ) in a focus of mucocutaneous leishmaniasis
  publication-title: Am. J. Trop. Med. Hyg.
  doi: 10.4269/ajtmh.2007.76.573
  contributor:
    fullname: Miles
– volume: 4
  start-page: a019604
  year: 2014
  ident: CR32
  article-title: Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosity
  publication-title: Cold Spring Harb. Perspect. Med.
  doi: 10.1101/cshperspect.a019604
  contributor:
    fullname: Berman
– volume: 23
  start-page: 4195
  year: 2014
  end-page: 4202
  ident: CR8
  article-title: Reproductive clonality in protozoan pathogens—truth or artefact?
  publication-title: Mol. Ecol.
  doi: 10.1111/mec.12872
  contributor:
    fullname: Llewellyn
– volume: 6
  start-page: 80
  year: 2012
  end-page: 92
  ident: CR66
  article-title: A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of strain w1118; -2; iso-3
  publication-title: Fly. (Austin)
  doi: 10.4161/fly.19695
  contributor:
    fullname: Cingolani
– ident: CR25
– volume: 9
  start-page: e1003905
  year: 2013
  ident: CR77
  article-title: Robust demographic inference from genomic and SNP data
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1003905
  contributor:
    fullname: Foll
– volume: 160
  start-page: 100
  year: 2008
  end-page: 106
  ident: CR55
  article-title: Fly transmission and mating of strain
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/j.molbiopara.2008.04.009
  contributor:
    fullname: Gibson
– volume: 27
  start-page: 3425
  year: 2018
  end-page: 3431
  ident: CR13
  article-title: Mitonuclear genomics challenges the theory of clonality in : reply to Tibayrenc and Ayala
  publication-title: Mol. Ecol.
  doi: 10.1111/mec.14809
  contributor:
    fullname: Van den Abbeele
– volume: 151
  start-page: 32
  year: 2015
  end-page: 50
  ident: CR41
  article-title: Reservoir host competence and the role of domestic and commensal hosts in the transmission of
  publication-title: Acta Trop.
  doi: 10.1016/j.actatropica.2015.05.029
  contributor:
    fullname: Cardinal
– volume: 28
  start-page: 10
  year: 2015
  end-page: 17
  ident: CR33
  article-title: The parasexual lifestyle of
  publication-title: Curr. Opin. Microbiol.
  doi: 10.1016/j.mib.2015.06.017
  contributor:
    fullname: Bennett
– volume: 98
  start-page: 7396
  year: 2001
  end-page: 7401
  ident: CR58
  article-title: Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of
  publication-title: PNAS
  doi: 10.1073/pnas.121187198
  contributor:
    fullname: Ayala
– volume: 294
  start-page: 161
  year: 2001
  end-page: 165
  ident: CR60
  article-title: Success and virulence in as the result of sexual recombination between two distinct ancestries
  publication-title: Science
  doi: 10.1126/science.1061888
  contributor:
    fullname: Boothroyd
– volume: 7
  start-page: e30377
  issue: 1
  year: 2012
  ident: CR65
  article-title: Fast Computation and Applications of Genome Mappability
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0030377
  contributor:
    fullname: Ribeca
– volume: 8
  start-page: e1002453
  year: 2012
  ident: CR28
  article-title: Inference of population structure using dense haplotype data
  publication-title: PLoS Genet
  doi: 10.1371/journal.pgen.1002453
  contributor:
    fullname: Falush
– volume: 37
  start-page: 111
  year: 2007
  end-page: 120
  ident: CR63
  article-title: Resolution of multiclonal infections of from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2006.08.002
  contributor:
    fullname: Yeo
– volume: 81
  start-page: 1084
  year: 2007
  end-page: 1097
  ident: CR67
  article-title: Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/521987
  contributor:
    fullname: Browning
– volume: 9
  start-page: e0004142
  year: 2015
  ident: CR62
  article-title: Comprehensive survey of domiciliary triatomine species capable of transmitting Chagas disease in southern Ecuador
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0004142
  contributor:
    fullname: Grijalva
– volume: 87
  start-page: 2414
  year: 1990
  end-page: 2418
  ident: CR26
  article-title: A clonal theory of parasitic protozoa: the population structures of , , , , , , and and their medical and taxonomical consequences
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.87.7.2414
  contributor:
    fullname: Ayala
– volume: 287
  start-page: 536
  year: 1980
  end-page: 538
  ident: CR9
  article-title: Evidence for diploidy and mating in trypanosomes
  publication-title: Nature
  doi: 10.1038/287536a0
  contributor:
    fullname: Tait
– volume: 34
  start-page: 65
  year: 1977
  end-page: 77
  ident: CR40
  article-title: Observations on the feeding and defecation patterns of three triatomine species (Hemiptera: Reduviidae)
  publication-title: Acta Trop.
  contributor:
    fullname: Jirón
– volume: 43
  start-page: 491
  year: 2011
  end-page: 498
  ident: CR64
  article-title: A framework for variation discovery and genotyping using next-generation DNA sequencing data
  publication-title: Nat. Genet.
  doi: 10.1038/ng.806
  contributor:
    fullname: DePristo
– volume: 15
  start-page: e1008042
  year: 2019
  ident: CR18
  article-title: Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1008042
  contributor:
    fullname: Inbar
– volume: 12
  year: 2011
  ident: CR24
  article-title: Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in strains revealed by array comparative genomic hybridization
  publication-title: BMC Genom.
  doi: 10.1186/1471-2164-12-139
  contributor:
    fullname: Tarleton
– volume: 10
  start-page: e1004092
  year: 2014
  ident: CR75
  article-title: Genomic confirmation of hybridisation and recent inbreeding in a vector-isolated population
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1004092
  contributor:
    fullname: Rogers
– volume: 9
  start-page: e01399
  year: 2018
  end-page: 18
  ident: CR38
  article-title: genome dynamics during environmental adaptation reveal strain-specific differences in gene copy number variation, karyotype instability, and telomeric amplification
  publication-title: mBio
  doi: 10.1128/mBio.01399-18
  contributor:
    fullname: Bussotti
– volume: 9
  start-page: e1003672
  year: 2013
  ident: CR50
  article-title: The mating competence of geographically diverse strains in their natural and unnatural sand fly vectors
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1003672
  contributor:
    fullname: Inbar
– volume: 12
  start-page: 623
  year: 2015
  end-page: 630
  ident: CR76
  article-title: Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection
  publication-title: Nat. Methods
  doi: 10.1038/nmeth.3407
  contributor:
    fullname: Ewing
– volume: 16
  start-page: 944
  year: 2000
  end-page: 945
  ident: CR78
  article-title: Artemis: sequence visualization and annotation
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/16.10.944
  contributor:
    fullname: Rutherford
– ident: CR37
– volume: 304
  start-page: 581
  year: 2004
  end-page: 584
  ident: CR74
  article-title: The fine-scale structure of recombination rate variation in the human genome
  publication-title: Science
  doi: 10.1126/science.1092500
  contributor:
    fullname: McVean
– volume: 13
  start-page: e0007392
  year: 2019
  ident: CR21
  article-title: Sexual reproduction in a natural population
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0007392
  contributor:
    fullname: Berry
– volume: 8
  start-page: e2960
  year: 2014
  ident: CR42
  article-title: & Dangles, O. Dynamics of sylvatic Chagas disease vectors in coastal Ecuador is driven by changes in land cover
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0002960
  contributor:
    fullname: Terán
– volume: 75
  start-page: 19
  year: 2011
  end-page: 47
  ident: CR2
  article-title: Acute and congenital Chagas disease
  publication-title: Adv. Parasitol.
  doi: 10.1016/B978-0-12-385863-4.00002-2
  contributor:
    fullname: Gilman
– volume: 1
  start-page: 4
  year: 2008
  ident: CR54
  article-title: The use of yellow fluorescent hybrids to indicate mating in
  publication-title: Parasit. Vectors
  doi: 10.1186/1756-3305-1-4
  contributor:
    fullname: Bailey
– volume: 40
  start-page: 1060
  year: 1986
  end-page: 1070
  ident: CR43
  article-title: Spatial and temporal factors affecting coexistence among sexual and clonal forms of
  publication-title: Evolution
  doi: 10.1111/j.1558-5646.1986.tb00573.x
  contributor:
    fullname: Vrijenhoek
– ident: CR79
– volume: 106
  start-page: 10224
  year: 2009
  end-page: 10229
  ident: CR19
  article-title: Extreme inbreeding in
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.0904420106
  contributor:
    fullname: Rougeron
– volume: 10
  start-page: 468
  year: 2017
  ident: CR36
  article-title: & Van den Abbeele, J. Evidence for viable and stable triploid parasites
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-017-2406-z
  contributor:
    fullname: Dujardin
– ident: CR27
– volume: 159
  start-page: 893
  year: 2001
  end-page: 905
  ident: CR51
  article-title: Gene genealogies in a metapopulation
  publication-title: Genetics
  contributor:
    fullname: Aliacar
– volume: 7
  start-page: 78
  year: 2014
  ident: CR56
  article-title: Mating compatibility in the parasitic protist
  publication-title: Parasit. Vectors
  doi: 10.1186/1756-3305-7-78
  contributor:
    fullname: Gibson
– volume: 22
  start-page: 2505
  year: 2003
  end-page: 2515
  ident: CR31
  article-title: Completion of a parasexual cycle in by induced chromosome loss in tetraploid strains
  publication-title: EMBO J.
  doi: 10.1093/emboj/cdg235
  contributor:
    fullname: Johnson
– volume: 136
  start-page: 343
  year: 1994
  end-page: 359
  ident: CR80
  article-title: Using allele frequencies and geographic subdivision to reconstruct gene trees within a species: molecular variance parsimony
  publication-title: Genetics
  contributor:
    fullname: Smouse
– volume: 391
  start-page: 82
  year: 2018
  end-page: 94
  ident: CR1
  article-title: Chagas disease
  publication-title: Lancet
  doi: 10.1016/S0140-6736(17)31612-4
  contributor:
    fullname: Molina
– volume: 5
  start-page: e961
  year: 2011
  ident: CR57
  article-title: Phylogeography and taxonomy of
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0000961
  contributor:
    fullname: Caccone
– ident: CR44
– volume: 3
  start-page: e186
  issue: 10
  year: 2007
  ident: CR49
  article-title: αADα Hybrids of Cryptococcus neoformans: Evidence of Same-Sex Mating in Nature and Hybrid Fitness
  publication-title: PLoS Genetics
  doi: 10.1371/journal.pgen.0030186
  contributor:
    fullname: Heitman
– volume: 206
  start-page: 429
  year: 2017
  end-page: 438
  ident: CR29
  article-title: Exploring evolutionary relationships across the genome using topology weighting
  publication-title: Genetics
  doi: 10.1534/genetics.116.194720
  contributor:
    fullname: Van Belleghem
– ident: CR3
– volume: 11
  year: 2010
  ident: CR69
  article-title: Discriminant analysis of principal components: a new method for the analysis of genetically structured populations
  publication-title: BMC Genet.
  doi: 10.1186/1471-2156-11-94
  contributor:
    fullname: Balloux
– volume: 5
  start-page: e11473
  year: 2016
  ident: CR14
  article-title: Population genomics reveals the origin and asexual evolution of human infective trypanosomes
  publication-title: eLife
  doi: 10.7554/eLife.11473
  contributor:
    fullname: Weir
– volume: 202
  start-page: 297
  year: 2016
  end-page: 312
  ident: CR53
  article-title: Coalescent times and patterns of genetic diversity in species with facultative sex: effects of gene conversion, population structure, and heterogeneity
  publication-title: Genetics
  doi: 10.1534/genetics.115.178004
  contributor:
    fullname: Agrawal
– volume: 39
  start-page: 1305
  year: 2009
  end-page: 1317
  ident: CR23
  article-title: Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in populations and expose contrasts between natural and experimental hybrids
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2009.04.001
  contributor:
    fullname: Lewis
– volume: 22
  start-page: 168
  year: 2006
  end-page: 174
  ident: CR4
  article-title: The evolution and diversity of kinetoplastid flagellates
  publication-title: Trends Parasitol.
  doi: 10.1016/j.pt.2006.02.006
  contributor:
    fullname: Lukeš
– volume: 324
  start-page: 265
  year: 2009
  end-page: 268
  ident: CR17
  article-title: Demonstration of genetic exchange during cyclical development of in the sand fly vector
  publication-title: Science
  doi: 10.1126/science.1169464
  contributor:
    fullname: Akopyants
– volume: 27
  start-page: 2544
  year: 2017
  end-page: 2551.e4
  ident: CR52
  article-title: Range expansion compromises adaptive evolution in an outcrossing plant
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2017.07.007
  contributor:
    fullname: Pannell
– volume: 37
  start-page: 589
  year: 2007
  end-page: 593
  ident: CR61
  article-title: Increased transmission potential of / hybrids
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2007.02.002
  contributor:
    fullname: Volf
– volume: 26
  start-page: 6524
  year: 2017
  end-page: 6538
  ident: CR12
  article-title: Discovery and genomic analyses of hybridization between divergent lineages of , causative agent of Animal African Trypanosomiasis
  publication-title: Mol. Ecol.
  doi: 10.1111/mec.14271
  contributor:
    fullname: Van den Broeck
– volume: 8
  start-page: 200
  year: 1998
  end-page: 211
  ident: CR34
  article-title: Recombination at work for meiosis
  publication-title: Curr. Opin. Genet. Dev.
  doi: 10.1016/S0959-437X(98)80142-1
  contributor:
    fullname: Nicolas
– volume: 288
  start-page: 1211
  year: 2000
  end-page: 1215
  ident: CR30
  article-title: Evidence for the evolution of bdelloid rotifers without sexual reproduction or genetic exchange
  publication-title: Science
  doi: 10.1126/science.288.5469.1211
  contributor:
    fullname: Meselson
– volume: 5
  start-page: 184
  year: 2005
  end-page: 186
  ident: CR71
  article-title: HIERFSTAT, a package for r to compute and test hierarchical F-statistics
  publication-title: Mol. Ecol. Notes
  doi: 10.1111/j.1471-8286.2004.00828.x
  contributor:
    fullname: Goudet
– volume: 41
  start-page: 539
  year: 2004
  end-page: 544
  ident: CR47
  article-title: A new hypothesis to explain geographic parthenogenesis
  publication-title: Ann. Zool. Fenn.
  contributor:
    fullname: Ebert
– start-page: 289
  year: 2004
  end-page: 290
  ident: CR70
  article-title: APE: analyses of phylogenetics and evolution in R language
  publication-title: Bioinformatics
  contributor:
    fullname: Strimmer
– volume: 27
  start-page: 3425
  year: 2018
  ident: 11771_CR13
  publication-title: Mol. Ecol.
  doi: 10.1111/mec.14809
  contributor:
    fullname: F Van den Broeck
– volume: 39
  start-page: 1305
  year: 2009
  ident: 11771_CR23
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2009.04.001
  contributor:
    fullname: MD Lewis
– volume: 391
  start-page: 82
  year: 2018
  ident: 11771_CR1
  publication-title: Lancet
  doi: 10.1016/S0140-6736(17)31612-4
  contributor:
    fullname: JA Pérez-Molina
– volume: 45
  start-page: 77
  year: 1991
  ident: 11771_CR48
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/0166-6851(91)90029-6
  contributor:
    fullname: W Gibson
– ident: 11771_CR79
  doi: 10.1007/978-1-4939-1438-8_19
– volume: 4
  start-page: a019604
  year: 2014
  ident: 11771_CR32
  publication-title: Cold Spring Harb. Perspect. Med.
  doi: 10.1101/cshperspect.a019604
  contributor:
    fullname: RJ Bennett
– volume: 1
  start-page: 4
  year: 2008
  ident: 11771_CR54
  publication-title: Parasit. Vectors
  doi: 10.1186/1756-3305-1-4
  contributor:
    fullname: W Gibson
– volume: 12
  start-page: 3493
  year: 2003
  ident: 11771_CR45
  publication-title: Mol. Ecol.
  doi: 10.1046/j.1365-294X.2003.01998.x
  contributor:
    fullname: C Vorburger
– volume: 79
  start-page: 1241
  year: 2010
  ident: 11771_CR46
  publication-title: J. Anim. Ecol.
  doi: 10.1111/j.1365-2656.2010.01726.x
  contributor:
    fullname: MP Lehto
– volume: 421
  start-page: 936
  year: 2003
  ident: 11771_CR22
  publication-title: Nature
  doi: 10.1038/nature01438
  contributor:
    fullname: MW Gaunt
– volume: 98
  start-page: 7396
  year: 2001
  ident: 11771_CR58
  publication-title: PNAS
  doi: 10.1073/pnas.121187198
  contributor:
    fullname: CA Machado
– ident: 11771_CR3
  doi: 10.1038/nature09221
– volume: 15
  start-page: e1008042
  year: 2019
  ident: 11771_CR18
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1008042
  contributor:
    fullname: E Inbar
– volume: 40
  start-page: 1060
  year: 1986
  ident: 11771_CR43
  publication-title: Evolution
  doi: 10.1111/j.1558-5646.1986.tb00573.x
  contributor:
    fullname: RA Schenck
– ident: 11771_CR27
  doi: 10.1101/283531
– volume: 8
  start-page: e1002453
  year: 2012
  ident: 11771_CR28
  publication-title: PLoS Genet
  doi: 10.1371/journal.pgen.1002453
  contributor:
    fullname: DJ Lawson
– volume: 10
  start-page: 468
  year: 2017
  ident: 11771_CR36
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-017-2406-z
  contributor:
    fullname: E Tihon
– volume: 288
  start-page: 1211
  year: 2000
  ident: 11771_CR30
  publication-title: Science
  doi: 10.1126/science.288.5469.1211
  contributor:
    fullname: D Mark Welch
– volume: 10
  start-page: e1004092
  year: 2014
  ident: 11771_CR75
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1004092
  contributor:
    fullname: MB Rogers
– ident: 11771_CR44
  doi: 10.1111/j.1095-8312.2004.00325.x
– volume: 105
  start-page: 4957
  year: 2008
  ident: 11771_CR73
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.0707314105
  contributor:
    fullname: IJ Tsai
– volume: 151
  start-page: 150
  year: 2015
  ident: 11771_CR20
  publication-title: Acta Trop.
  doi: 10.1016/j.actatropica.2015.05.007
  contributor:
    fullname: LA Messenger
– volume: 8
  start-page: 200
  year: 1998
  ident: 11771_CR34
  publication-title: Curr. Opin. Genet. Dev.
  doi: 10.1016/S0959-437X(98)80142-1
  contributor:
    fullname: KN Smith
– volume: 143
  start-page: 12
  year: 2005
  ident: 11771_CR10
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/j.molbiopara.2005.04.009
  contributor:
    fullname: A MacLeod
– volume: 16
  start-page: 944
  year: 2000
  ident: 11771_CR78
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/16.10.944
  contributor:
    fullname: K Rutherford
– volume: 7
  start-page: e30377
  issue: 1
  year: 2012
  ident: 11771_CR65
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0030377
  contributor:
    fullname: Thomas Derrien
– volume: 8
  start-page: e2960
  year: 2014
  ident: 11771_CR42
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0002960
  contributor:
    fullname: MJ Grijalva
– volume: 15
  start-page: 185
  year: 2005
  ident: 11771_CR7
  publication-title: Curr. Biol.
  contributor:
    fullname: MA Ramesh
– volume: 34
  start-page: 65
  year: 1977
  ident: 11771_CR40
  publication-title: Acta Trop.
  contributor:
    fullname: R Zeledón
– volume: 41
  start-page: 539
  year: 2004
  ident: 11771_CR47
  publication-title: Ann. Zool. Fenn.
  contributor:
    fullname: CR Haag
– volume: 5
  start-page: e961
  year: 2011
  ident: 11771_CR57
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0000961
  contributor:
    fullname: O Balmer
– volume: 106
  start-page: 10224
  year: 2009
  ident: 11771_CR19
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.0904420106
  contributor:
    fullname: V Rougeron
– volume: 13
  start-page: e0007392
  year: 2019
  ident: 11771_CR21
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0007392
  contributor:
    fullname: ASF Berry
– volume: 11
  year: 2010
  ident: 11771_CR69
  publication-title: BMC Genet.
  doi: 10.1186/1471-2156-11-94
  contributor:
    fullname: T Jombart
– ident: 11771_CR25
  doi: 10.1016/B978-0-12-801029-7.00021-6
– volume: 9
  start-page: e0004142
  year: 2015
  ident: 11771_CR62
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0004142
  contributor:
    fullname: MJ Grijalva
– volume: 6
  start-page: 80
  year: 2012
  ident: 11771_CR66
  publication-title: Fly. (Austin)
  doi: 10.4161/fly.19695
  contributor:
    fullname: P Cingolani
– volume: 151
  start-page: 32
  year: 2015
  ident: 11771_CR41
  publication-title: Acta Trop.
  doi: 10.1016/j.actatropica.2015.05.029
  contributor:
    fullname: RE Gürtler
– volume: 5
  start-page: e1363
  year: 2011
  ident: 11771_CR59
  publication-title: PLoS Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0001363
  contributor:
    fullname: MD Lewis
– volume: 37
  start-page: 111
  year: 2007
  ident: 11771_CR63
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2006.08.002
  contributor:
    fullname: M Yeo
– volume: 160
  start-page: 100
  year: 2008
  ident: 11771_CR55
  publication-title: Mol. Biochem. Parasitol.
  doi: 10.1016/j.molbiopara.2008.04.009
  contributor:
    fullname: L Peacock
– volume: 5
  start-page: 184
  year: 2005
  ident: 11771_CR71
  publication-title: Mol. Ecol. Notes
  doi: 10.1111/j.1471-8286.2004.00828.x
  contributor:
    fullname: J Goudet
– volume: 9
  start-page: e1003905
  year: 2013
  ident: 11771_CR77
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1003905
  contributor:
    fullname: L Excoffier
– volume: 23
  start-page: 4195
  year: 2014
  ident: 11771_CR8
  publication-title: Mol. Ecol.
  doi: 10.1111/mec.12872
  contributor:
    fullname: JD Ramírez
– volume: 136
  start-page: 343
  year: 1994
  ident: 11771_CR80
  publication-title: Genetics
  doi: 10.1093/genetics/136.1.343
  contributor:
    fullname: L Excoffier
– volume: 27
  start-page: 2156
  year: 2011
  ident: 11771_CR72
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btr330
  contributor:
    fullname: P Danecek
– volume: 26
  start-page: 6524
  year: 2017
  ident: 11771_CR12
  publication-title: Mol. Ecol.
  doi: 10.1111/mec.14271
  contributor:
    fullname: E Tihon
– volume: 3
  start-page: e186
  issue: 10
  year: 2007
  ident: 11771_CR49
  publication-title: PLoS Genetics
  doi: 10.1371/journal.pgen.0030186
  contributor:
    fullname: Xiaorong Lin
– volume: 9
  start-page: e1003672
  year: 2013
  ident: 11771_CR50
  publication-title: PLoS Genet.
  doi: 10.1371/journal.pgen.1003672
  contributor:
    fullname: E Inbar
– volume: 5
  start-page: e12613
  year: 2016
  ident: 11771_CR39
  publication-title: eLife
  doi: 10.7554/eLife.12613
  contributor:
    fullname: H Imamura
– volume: 202
  start-page: 297
  year: 2016
  ident: 11771_CR53
  publication-title: Genetics
  doi: 10.1534/genetics.115.178004
  contributor:
    fullname: M Hartfield
– volume: 28
  start-page: 10
  year: 2015
  ident: 11771_CR33
  publication-title: Curr. Opin. Microbiol.
  doi: 10.1016/j.mib.2015.06.017
  contributor:
    fullname: RJ Bennett
– volume: 87
  start-page: 2414
  year: 1990
  ident: 11771_CR26
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.87.7.2414
  contributor:
    fullname: M Tibayrenc
– volume: 76
  start-page: 573
  year: 2007
  ident: 11771_CR16
  publication-title: Am. J. Trop. Med. Hyg.
  doi: 10.4269/ajtmh.2007.76.573
  contributor:
    fullname: D Nolder
– volume: 23
  start-page: 254
  year: 2006
  ident: 11771_CR68
  publication-title: Mol. Biol. Evol.
  doi: 10.1093/molbev/msj030
  contributor:
    fullname: DH Huson
– volume: 22
  start-page: 168
  year: 2006
  ident: 11771_CR4
  publication-title: Trends Parasitol.
  doi: 10.1016/j.pt.2006.02.006
  contributor:
    fullname: AGB Simpson
– volume: 5
  start-page: e11473
  year: 2016
  ident: 11771_CR14
  publication-title: eLife
  doi: 10.7554/eLife.11473
  contributor:
    fullname: W Weir
– volume: 12
  year: 2011
  ident: 11771_CR24
  publication-title: BMC Genom.
  doi: 10.1186/1471-2164-12-139
  contributor:
    fullname: TA Minning
– volume: 46
  start-page: 819
  year: 1986
  ident: 11771_CR5
  publication-title: Cell
  doi: 10.1016/0092-8674(86)90063-2
  contributor:
    fullname: R Benne
– volume: 22
  start-page: 2505
  year: 2003
  ident: 11771_CR31
  publication-title: EMBO J.
  doi: 10.1093/emboj/cdg235
  contributor:
    fullname: RJ Bennett
– ident: 11771_CR37
  doi: 10.1099/mgen.0.000223
– volume: 24
  start-page: 181
  year: 2014
  ident: 11771_CR11
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2013.11.044
  contributor:
    fullname: L Peacock
– volume: 206
  start-page: 429
  year: 2017
  ident: 11771_CR29
  publication-title: Genetics
  doi: 10.1534/genetics.116.194720
  contributor:
    fullname: SH Martin
– volume: 159
  start-page: 893
  year: 2001
  ident: 11771_CR51
  publication-title: Genetics
  doi: 10.1093/genetics/159.2.893
  contributor:
    fullname: J Wakeley
– start-page: 289
  volume-title: Bioinformatics
  year: 2004
  ident: 11771_CR70
  contributor:
    fullname: E Paradis
– volume: 304
  start-page: 581
  year: 2004
  ident: 11771_CR74
  publication-title: Science
  doi: 10.1126/science.1092500
  contributor:
    fullname: GAT McVean
– volume: 7
  start-page: 78
  year: 2014
  ident: 11771_CR56
  publication-title: Parasit. Vectors
  doi: 10.1186/1756-3305-7-78
  contributor:
    fullname: L Peacock
– volume: 37
  start-page: 589
  year: 2007
  ident: 11771_CR61
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2007.02.002
  contributor:
    fullname: P Volf
– volume: 12
  start-page: 623
  year: 2015
  ident: 11771_CR76
  publication-title: Nat. Methods
  doi: 10.1038/nmeth.3407
  contributor:
    fullname: AD Ewing
– volume: 81
  start-page: 1084
  year: 2007
  ident: 11771_CR67
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/521987
  contributor:
    fullname: SR Browning
– volume: 9
  start-page: e01399
  year: 2018
  ident: 11771_CR38
  publication-title: mBio
  doi: 10.1128/mBio.01399-18
  contributor:
    fullname: G Bussotti
– volume: 294
  start-page: 161
  year: 2001
  ident: 11771_CR60
  publication-title: Science
  doi: 10.1126/science.1061888
  contributor:
    fullname: ME Grigg
– volume: 61
  start-page: 1157
  year: 1990
  ident: 11771_CR6
  publication-title: Cell
  doi: 10.1016/0092-8674(90)90674-4
  contributor:
    fullname: N Agabian
– volume: 36
  start-page: 1383
  year: 2006
  ident: 11771_CR15
  publication-title: Int. J. Parasitol.
  doi: 10.1016/j.ijpara.2006.06.019
  contributor:
    fullname: C Ravel
– volume: 13
  start-page: 274
  year: 2011
  ident: 11771_CR35
  publication-title: Cell. Microbiol
  doi: 10.1111/j.1462-5822.2010.01534.x
  contributor:
    fullname: Y Sterkers
– volume: 43
  start-page: 491
  year: 2011
  ident: 11771_CR64
  publication-title: Nat. Genet.
  doi: 10.1038/ng.806
  contributor:
    fullname: MA DePristo
– volume: 324
  start-page: 265
  year: 2009
  ident: 11771_CR17
  publication-title: Science
  doi: 10.1126/science.1169464
  contributor:
    fullname: NS Akopyants
– volume: 75
  start-page: 19
  year: 2011
  ident: 11771_CR2
  publication-title: Adv. Parasitol.
  doi: 10.1016/B978-0-12-385863-4.00002-2
  contributor:
    fullname: C Bern
– volume: 27
  start-page: 2544
  year: 2017
  ident: 11771_CR52
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2017.07.007
  contributor:
    fullname: SC González-Martínez
– volume: 287
  start-page: 536
  year: 1980
  ident: 11771_CR9
  publication-title: Nature
  doi: 10.1038/287536a0
  contributor:
    fullname: A Tait
SSID ssj0000391844
Score 2.5472739
Snippet Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi , the parasitic agent of Chagas...
Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi, the parasitic agent of Chagas...
Here, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi, the causative agent of Chagas disease. These findings have implications...
SourceID doaj
swepub
pubmedcentral
proquest
crossref
pubmed
springer
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 3972
SubjectTerms 45/23
631/158/1469
631/181/2474
631/181/457
631/326/417/2551
Animals
Chagas disease
Chagas Disease - parasitology
Chiroptera - parasitology
Ecuador
Epidemiology
Exchanging
Genetic engineering
Genetic Variation
Genetics, Population
Genome, Protozoan
Genomes
Humanities and Social Sciences
Hybridization
Life cycles
Medicin och hälsovetenskap
Meiosis
multidisciplinary
Parasites
Parasitic diseases
Phenotypes
Protozoa
Public health
Recombination, Genetic
Reproduction - genetics
Rodentia - parasitology
Science
Science (multidisciplinary)
Sequence Analysis, DNA
Sex
Triatominae - parasitology
Trypanosoma cruzi
Trypanosoma cruzi - genetics
Vector-borne diseases
Vectors
Virulence
SummonAdditionalLinks – databaseName: Directory of Open Access Journals
  dbid: DOA
  link: http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwEB5BJSQuCMorUKogcQOrm9jx4wilFRe4UCRulu3YNEIkaNOV6P56xnY2EKjohUMutpU48x6N_Q3Ai8YI3ihpSRsUI8xRSqzwgShlJXqPwLhNrRM-ig-f5duTCJMzt_qKZ8IyPHAm3BGzKJHGORnQeaq6shwdtjSUO_S9NORrviv-WzKVbDBVmLqw6ZbMisqjkSWbgBENiXXKimwXnigB9l8VZf59WHKumP6BLpo80ulduDOFkuXr_Av34Ibv9-FWbi55eR_ke98NOFWO_kfZ9eXxuflixnKqyJQR8ztWjsuz9SVahGEcvpnSrTfb7gF8Oj05O35Hpj4JxPFaXhDmV9y1xgrURuuVRCLzENBwUKsa45nwlVOYCWK2Ir1yrQ_Sc2Mpo4IFDNjoQ9jrh94_hrKOGSs6eSZMwJdR2XDTeuNVwLCKK17Ayx3N9PcMh6FTGZtKnSmskcIJQbzS2wLeRLLOKyOUdRpABuuJwfo6BhdwsGOKnvRr1BG0R6WGpwU8n6dRM2K5w_R-2KQ1rGkwfMFdP8o8nHdCMQusuKoLEAvuLra6nOm784S-zUVdY5BZwKudHPza1r9IUWdZWX4BnaSexr928dGjx2wswaYx9eR_0O8p3K6j1MciGD2AvYv1xj-Dm2O7OUw68xOP5Rd2
  priority: 102
  providerName: Directory of Open Access Journals
Title Meiotic sex in Chagas disease parasite Trypanosoma cruzi
URI https://link.springer.com/article/10.1038/s41467-019-11771-z
https://www.ncbi.nlm.nih.gov/pubmed/31481692
https://www.proquest.com/docview/2283959000
https://search.proquest.com/docview/2284552446
https://pubmed.ncbi.nlm.nih.gov/PMC6722143
http://kipublications.ki.se/Default.aspx?queryparsed=id:141790549
https://doaj.org/article/4b305acc8f064921b66238a36c6173f8
Volume 10
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwEB2xlUC9IL5JKZWRuEG6Tew49hGWVlyKkCgSN8t27DYqm1SbrkT313fsJAsBxIFDLraVjMbjmTcZ-xngdaFLXkhh0spLljJLaWpK51MpjcDo4Rk38eqEL-Wnb-LDcaDJKcazMHHTvjX1YfN9edjUF3Fv5dXSzsd9YvPPpwte5jnG-fkMZogNf0nRo_ulErMWNhyQOaJi3rHoDhDMpKFEmaWbXbhHMQ_IuMwn8SjS9v8Na_65ZXJbN_2NYzTGpZMHcH8AlORdL_hDuOOaR3C3v2Ly5jGIU1e32EU694PUDVlc6HPdkaEuQwLzd6gfk7PVDfqFtmuXmtjVelM_ga8nx2eLj-lwW0JqeS6uU-aOuK20KXFNGicFqpp7j-6DGllox0qXWYn5IOYswklbOS8c14YyWjKPsI0-hZ2mbdxzIHnIWzHUs1J7fBkVBdeV0056BFdc8gTejDpTVz0phorFbCpUr2yFyo484pnaJPA-qHU7MhBax4Z2da6GaVXMoOPR1gqPGEnmmeGIy4Sm3CLEol4ksD9OihpWWacCdY-M154m8GrbjesjFD1049p1HMOKAkEMSv2sn8OtJKMNJFBOZnci6rQHTTJycA8mmMDb0Q5-ivUvVeS9rUy_gKFSDe2XdXhU5zAni-RpTO79t3QvYDcPVh_qX3Qfdq5Xa_cSZl21Poj_Hg7iyrkFvZYZ5w
link.rule.ids 230,315,729,782,786,866,887,2106,27933,27934,53801,53803
linkProvider National Library of Medicine
linkToHtml http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwEB3RIqAXPgsECgSJG6S7iR3HPsLSqohuhcQicbNsx24j2KTadCW6v56xkywsIA495GJbycTjmXmjsZ8BXuWqYLngOimdoAk1hCS6sC4RQnOMHo4yHa5O-FycfOXvDzxNTj6chQmb9o2u9uvv8_26Ogt7K8_nZjTsExt9mk5YkWUY50dbcB3tdZz-lqQHB0wE5i20PyIzJnzU0uAQEM4kvkiZJqsduEkwE0iZyDYiUiDu_xfa_HvT5Lpy-gfLaIhMh3eu-E934XYPReO3Xfc9uGbr-3Cju5zy8gHwqa0a7Ipb-yOu6nhypk5VG_cVndhzhvvKczxbXKJHadpmrmKzWK6qXfhyeDCbHCX9PQuJYRm_SKgdM1MqXaA1ays4Kok5h46HaJErSwubGoGZJGY73ApTWsctU5pQUlCHgI88hO26qe1jiDOf8SJIoIVy-DLCc6ZKq6xwCMuYYBG8HuZannd0GjKUwQmXnZIkKikwkKdyFcE7r471SE-FHRqaxansJ09SjS5LGcMdoiuRpZohouOKMIPgjDgewd6gTNnbZys96Y8IF6ZG8HLdjZblyyWqts0yjKF5jvAHpX7U6X4tybB2Iig2VsWGqJs9qPjA3t0rOoI3w_r5Jdb_piLr1tjmFzDIyr79W-Uf2VrM5gLtGhVPrizdC7h1NJsey-MPJx-fwk7mLcdX0cgebF8slvYZbLXl8nmwu5_HLS50
linkToPdf http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Nb9QwEB3RIqpe-C4ECgSJG6S7GzuOfYRtVyBoVYkicbNsx24j2GS16Up0fz1jJ1kIIA5wyCW2konHM_NG47wBeJGpnGWC66RwgibUEJLo3LpECM0xejjKdGid8DE_-cwPjzxNzqbVVzi0b3R5UH2dH1TlRThbuZibUX9ObHR6PGV5mmKcHy0KN9qC62izY_JToh6cMBGYu9DuN5kx4aOGBqeAkCbxhcpJst6FHYLZwISJdBCVAnn_nxDn7wcnN9XTX5hGQ3Sa3fqP77oNNztIGr9up9yBa7a6CzfaJpVX94Af27LGobix3-KyiqcX6lw1cVfZiT13uK9Ax2fLK_QsdVPPVWyWq3V5Hz7Njs6mb5Ou30JiWMovE2rHzBRK52jV2gqOymLOoQMiWmTK0txOjMCMErMeboUprOOWKU0oyalD4Ef2YLuqK_sQ4tRnvggWaK4cPozwjKnCKiscwjMmWAQv-_WWi5ZWQ4ZyOOGyVZRERQUm8olcR_DGq2Qz01Nihxv18lx2CyipRteljOEOUZZIJ5ohsuOKMIMgjTgewX6vUNnZaSM9-Y8IjVMjeL4ZRgvzZRNV2XoV5tAsQxiEUj9o9b-RpN8_EeSDnTEQdTiCyg8s3p2yI3jV76EfYv1tKdJ2nw3fgMFWdve_lP6SjcWsLtCvUfHon6V7BjunhzP54d3J-8ewm3rj8cU0sg_bl8uVfQJbTbF6GkzvO1PbMPQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Meiotic+sex+in+Chagas+disease+parasite+Trypanosoma+cruzi&rft.jtitle=Nature+communications&rft.au=Schwabl%2C+Philipp&rft.au=Imamura%2C+Hideo&rft.au=Van+den+Broeck%2C+Frederik&rft.au=Costales%2C+Jaime+A.&rft.date=2019-09-03&rft.pub=Nature+Publishing+Group+UK&rft.eissn=2041-1723&rft.volume=10&rft.issue=1&rft_id=info:doi/10.1038%2Fs41467-019-11771-z&rft.externalDocID=10_1038_s41467_019_11771_z
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2041-1723&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2041-1723&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2041-1723&client=summon