Bone sialoprotein-coated femoral implants are osteoinductive but mechanically compromised

Aseptic loosening of femoral implants in total hip replacement remains an unsolved orthopaedic problem. This paper investigates the potential role of bone sialoprotein (BSP) in enhancing bone-implant adherence. As BSP is osteoinductive in rat calvarial models, we investigated whether BSP is similarl...

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Bibliographic Details
Published in:	Journal of orthopaedic research Vol. 22; no. 3; pp. 641 - 646
Main Authors:	O'Toole, Gary C, Salih, E, Gallagher, C, FitzPatrick, D, O'Higgins, N, O'Rourke, S.K
Format:	Journal Article
Language:	English
Published:	Hoboken Elsevier Ltd 01-05-2004 Wiley Subscription Services, Inc., A Wiley Company Blackwell Publishing Ltd
Subjects:	Animals Arthroplasty, Replacement, Hip Biomechanical Phenomena Bone sialoprotein Coated Materials, Biocompatible - pharmacology Female Femur - physiology Femur - surgery Integrin-Binding Sialoprotein Osteogenesis - drug effects Osteoinduction Rats Rats, Wistar Sialoglycoproteins - pharmacology Bone sialoprotein Osteoinduction
Online Access:	Get full text
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